隐丹参酮

隐丹参酮对大鼠肝微粒体CYP酶的影响

Effects of Cryptotanshinone on Cytochrome P450 Isoforms in Rat Liver Microsomes

隐丹参酮和二氢丹参酮对宫颈癌Hela细胞均有较好的细胞毒性和放射增敏作用，对肝癌移植的荷瘤小鼠，具有抑制和延迟肿瘤生长的作用。

Cryptotanshinone and Dihydrotanshinone had significant cytotoxicity and radiosensitization effects on cervical cancer Hela cell . In addition , the capacity of delaying tumor growth in nude mice transplanted with hepatoma cell was evaluated .

根的愈伤组织中丹参酮IIA和隐丹参酮含量较高，丹酚酸B含量较低。

The content of salvianolic acid B in the root callus was the lowest .

隐丹参酮对TNF-α诱导的人脐静脉内皮细胞粘附分子ICAM-1表达的作用

The effect of cryptotanshinone on the expression of ICAM-1 in TNF - α - induced human umbilical vein endothelial cells

隐丹参酮和丹参酮IIA滤纸基质室温磷光法的研究

Study on the Room Temperature Phosphorescence of Cryptotanshinone and Tanshinone IIA

考察了隐丹参酮和丹参酮IIA的滤纸基质室温磷光法（PS-RTP）特性。

Room temperature phosphorescence of cryptotanshinone and tanshinone IIA has been studied in detail .

结果：其中丹参酮A的释放符合Higuchi方程，而隐丹参酮则在第一天有突释现象。

RESULTS : Release of tanshinone ⅱ A agrees with Higuchi equation while cryptotanshinone performs a significant first burst effect in the very first day .

方法用Caco-2细胞单层模型研究隐丹参酮的双向转运，并考察时间、药物浓度及抑制剂对隐丹参酮吸收的影响。

Methods Caco-2 cell monolayer model was used to investigate the bi-directional transport of cryptotanshinone . The effect of time , drug concentration and inhibitors on the absorption of cryptotanshinone was studied .

采用电喷雾电离质谱（ESI-MS）和电子轰击质谱（EI-MS）两种质谱技术，对隐丹参酮的结构和裂解途径分别进行了研究。

Electron Spray Ionization Mass Spectrometry ( ESI-MS ) and Electron Ionization Mass Spectrometry ( EI-MS ) were used to elucidate the structure and fragmentation pathway of Cryptotanshinone ( CT ) .

目的建立大鼠血浆中丹参酮ⅡA和隐丹参酮的HPLC-UV检测法，并研究丹参脂溶性成分在大鼠体内的药动学。

Objective To establish a sensitive HPLC method with UV detection for the determination of tanshinone ⅱ _A ( TS ⅱ _A ) and cryptotanshinone ( CT ) in rat plasma and to study pharmacokinetics of Radix Salviae Miltiorrhizae ( RSM ) liposoluble components in rat in vivo .

隐丹参酮在小肠吸收机制的实验研究

Experimental study on the absorption mechanism of cryptotanshinone single-pass intestinal perfusion model

隐丹参酮的电子电离和电喷雾电离质谱分析

Analysis of Cryptotanshinone by Electron Spray Ionization Mass Spectrometry and Electron Ionization Mass Spectrometry

隐丹参酮固体分散体的制备及性质研究

Preparation of cryptotanshinone solid dispersion and its properties

基因芯片研究隐丹参酮对胰岛素抵抗卵巢颗粒细胞基因表达的影响

Studies on the Effect of Cryptotanshinone on Insulin Resistant Ovarial Granular Cells by DNA Microarray

丹参浸膏是丹参经乙醇提取的脂溶性成分，主要有隐丹参酮、丹参酮Ⅰ和丹参酮ⅡA三种。

The fat-soluble ingredients are extracted from it by ethyl alcohol , in which mainly are Cryptotanshinone , Tanshinone ⅰ and Tanshinone ⅱ A.

并且在适宜水分下，丹参酮ⅡA、二氢丹参酮和丹参酮Ⅰ的积累量较高；隐丹参酮在中度水分胁迫下含量较高。

And the accumulation of Tanshinone ⅱ A , Dihydro tanshinone and Tanshinone are higher in the root of Salvia miltiorrhiza when it under the suitable water stress .

结果：（1）不同浓度的芦荟大黄素（12.5-50μM）和隐丹参酮（2.5-10μM）作用于t-HSC/C1-6细胞后明显抑制t-HSC/C1-6细胞生长率，呈剂量和时间依赖性。

Results : ( 1 ) Treatment of t-HSC / Cl-6 cells with these two compounds ( 12.5-50 μ M aloe emodin or 2.5-10 uM cryptotanshinone ) both inhibited t-HSC / Cl-6 cell viability in a dose - and time-dependent manner .