采用结扎左冠状动脉前降支30min,再灌注40min复制在体大鼠心肌缺血再灌注损伤(IRI)的模型,结扎前10min分别舌下静脉注射倒卵叶五加总皂甙(SAOH)50mg/kg、100mg/kg。
Myocardial ischemia reperfusion injury ( IRI ) model was induced by left descending anterior coronary artery ( LAD ) ligation for 30 min , followed by 40 min of reperfusion .