首过消除
- 网络first pass elimination;first-pass elimination;first psaa elimination;first pass eliminaiton
首过消除
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高剂量组的血液含量为0.75μg/ml,但是出现了首过消除现象;
And results was manifestative that plasma concentration was 0.65 μ g / ml by low doses and 0.75 μ g / ml by high dose . Moreover , the first-pass elimination in high dose happened ;
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透皮给药作为一种新型给药方式,已成为国内外研究热点,其具有给药方便,避免药物的肝脏首过效应及容易消除不良反应等优点。
Transdermal delivery , a new delivery stlye , is a research focus in home and abroad for its easy delivery , no first pass effect on liver and eliminating adverse reactions .