酪氨酸蛋白激酶受体

酪氨酸蛋白激酶受体B在人卵泡中的表达及意义

Expression of tyrosine kinase receptor B in human follicle

bFGF的许多生理功能与酪氨酸蛋白激酶受体活性及丝裂原激活蛋白激酶（MAPK）有关。PKB又称Akt，是一种丝氨酸／苏氨酸蛋白激酶。

Much of the function of bFGF is related with the activity of tyrosine protein kinase receptor and MAPK . PKB , which is also called Akt , is one of Ser / Thr protein kinase .

胶质细胞系源性神经营养因子（GDNF）可以通过跨膜的酪氨酸蛋白激酶受体RET激活细胞内两条信号通路，即磷脂酰肌醇3激酶（PI3K）信号通路和Ras/Raf/MEK/Erk信号通路。

It is known that through binding to the tyrosine kinase receptor RET , the glial cell line-derived neurotrophic factor ( GDNF ) activates two intracellular signaling pathways : the phosphatidylinositol 3 kinase ( PI3K ) pathway and the Ras / Raf / MEK / Erk pathway .

胰岛素样生长因子I受体（insulin-likegrowthfactorIreceptor，IGF-IR）为跨膜蛋白，是酪氨酸蛋白激酶类受体家族的主要成员之一。

Type I insulin-like growth factor receptor ( IGF-IR ) is a transmembrane protein . And it is also one of the main members of the family of receptor protein tyrosine kinases ( PTKs ) .

目的：检测酪氨酸蛋白激酶EphB2受体在不同癌组织中的表达情况，探讨其与恶性肿瘤形成的关系。

Objective : To study the expression of EphB_2 receptor tyrosine kinase in several kinds of carcinoma tissues , and discussion on EphB_2 receptor is associated with cancer development .

酪氨酸蛋白激酶EphB4受体在几种癌组织中的表达

Expression of EphB_4 receptor tyrosine kinase in several kinds of carcinoma tissues

受体酪氨酸激酶是一个具有内在酪氨酸蛋白激酶活性的膜受体超家族，成员众多，信号转导通路复杂多样。

Receptor tyrosine kinase ( RTK ), a membrane receptor superfamily with intrinsic protein tyrosine kinase activity , has many members and complicated signal transduction pathways .