盐酸氟西汀

HPLC法测定盐酸氟西汀的有关物质及其胶囊的含量

Determination of Related Substances in Fluoxetine Hydrochloride and Assay of Its Capsules by HPLC

目的：对国产盐酸氟西汀（Flu）胶囊进行相对生物利用度研究。

AIM : To study the relative bioavailability of domestic fluoxetine hydrochloride ( Flu ) capsules .

盐酸氟西汀治疗下发生皮肤边缘带B细胞淋巴瘤：以体外T细胞增殖抑制为依据的有关发病机制的一项假说

Cutaneous marginal zone B-cell lymphoma in the setting of fluoxetine therapy : A hypothesis regarding pathogenesis based on in vitro suppression of T-cell-proliferative response

目的评价盐酸氟西汀治疗非典型性牙痛（AO）的疗效。

Objective To evaluate the outcome of treatment with fluoxertine hydrochloride ( Prozac ) in patients with atypical odontalgia ( AO ) .

目的：观察盐酸氟西汀片治疗灼口综合征（BMS）的临床疗效。

PURPOSE : To investigate the effect of fluoxetine hydrochloride on patients with burning mouth syndrome .

乙组22例患者除应用行为疗法外，同时口服盐酸氟西汀25mg，每晚1次，连用4周。

Group B were treated by 25 mg fluoxetine daily and behavior therapeutics at same time .

【方法】选择雄性SD大鼠70只，分为空白对照组、模型组、盐酸氟西汀组、半夏厚朴汤极小、低、中、高剂量，每组10只。

【 Methods 】 seventy male SD rats were randomly divided into seven groups : normal control group , model group , Fluoxetine group and Pinellia and Magnolia Bark Decoction extreme low 、 low 、 mid and high groups .

应用盐酸氟西汀可显著改善抑郁症大鼠的抑郁行为，同时增加DG神经前体细胞的数目，其增殖也增强。

Administration of fluoxetine hydrochloride was shown to dramatically improve the depression behavior , increase the number of DG neural precursor cells and enhance the regeneration of these cells in rats with depression .

结果口服盐酸氟西汀分散片或胶囊后，氟西汀的Cmax分别为（16.96±5.40）和（17.02±4.73）ng／ml；

Results The data for fluoxetine HCl dispersible tablets and its capsule were expressed respectively as following : Cmax was ( 16.96 ± 5.40 ) and ( 17.02 ± 4.73 ) ng / mL ;

方法：对60例儿童抑郁症患者分别用盐酸氟西汀胶囊或氯丙咪嗪治疗6周，以汉密尔顿抑郁量表（HAMD）评定药物疗效，TESS评定不良反应。

Methods : 60 cases of depressive children were treated with fluoxetine hydrochloride and clomipramine respectively for 6 weeks . HAMD was used to evaluate the efficacy and TESS was used to assess the side effects .

方法对63例强迫症患者予盐酸氟西汀治疗，以YBOCS减分率作为疗效评定，以TESS量表评定不良反应。

Methods : Fluoxetine Hydrochloride were administered to 63 patients with OCD . The reduction of Y BOCS was used for therapeutic effect evaluation and TESS for adverse effect assessment .

给予34名癌症患者服用盐酸氟西汀（百忧解）每日20mg治疗8周后，再次进行HAMD和SCL-90评分，并与治疗前进行比较。

34 old patients with cancer was given Fluoxetine , up to 20mg / day , for 8 weeks , and compared their standard of HAMD and SCL-90 now to their standard before the treatment .

结果盐酸氟西汀组治疗后患者Zung量表积分与治疗前比较有显著下降（P<0.01），患者的收缩压及舒张压与治疗前比较也有显著下降（P<0.05）。

Results the blood pressure and the Zung scores of the group treated by PROZAC and normal hypotensor was significantly reduced after 8 weeks ( P < 0.05 and P < 0.01 ) .

抗抑郁药物PROZAC（盐酸氟西汀）能明显改善病程3、6月时神经功能缺损，病程12月时不仅抑郁症状减轻，日常生活能力改善，神经功能缺损减轻尤为显著。

Anti-Depressive drug PROZAC ( Fluoxetine Hydrochloride ) can ameliorate neurologic impairment during the course of 3 and 6 months , furthermore relieve depression symptom and defect of ability in daily living and more neurologic impairment at 12 months .

盐酸氟西汀治疗强迫症临床开放性对照研究

A Open-controled Study of Fluoxetine in the Treatment of Obsessive-compulsive Disorder

盐酸氟西汀治疗反社会人格障碍患者攻击行为的对照研究

Comparison study of fluoxetine effects on aggression of antisocial personality disorder patients

盐酸氟西汀联合雌激素治疗绝经期抑郁症的临床观察

Observation of effect in treating menopausal depression by fluoxetine combined with estrogen

盐酸氟西汀治疗卒中后病理性哭笑

Fluoxetine hydrochloride for patients with poststroke pathological laughing and crying

盐酸氟西汀治疗脑卒中后抑郁及神经功能缺损的疗效观察

Clinical Observation of Fluoxetine on Post-stroke Depression and Neurologic Impairment

国产盐酸氟西汀治疗抑郁症的临床分析

Clinical analyses on treating depression with domestic fluoxetine

盐酸氟西汀分散片和胶囊的生物等效性研究

The bioequivalence study of fluoxetine HCl capsule and its dispersible tablets in healthy volunteers

它的化学名称为盐酸氟西汀，这显然不够朗朗上口。

Its chemical name is fluoxetine hydrochloride , not the most felicitous of terms .

结论：盐酸氟西汀和氯丙咪嗪改善血管性抑郁患者抑郁症状的疗效相近；

CONCLUSION : The therapeutic effect of fluoxetine hydrochloride was close to that of clomipramine .

国产盐酸氟西汀胶囊的相对生物利用度

Relative bioavailability of domestic fluoxetine hydrochloride capsules

目的：建立反相高效液相色谱法测定盐酸氟西汀胶囊的含量。

Objective : a rapid RP-HPLC method was established for the determination of fluoxetine in capsules .

联用盐酸氟西汀与匹维溴铵治疗腹泻型肠易激综合征的对照研究

Controlled study of combined usage of fluoxetine hydrochloride and pinaverium bromide on curing diarrhea predominant irritable bowel syndrome

盐酸氟西汀对抑郁症模型小鼠神经肽Y表达的研究

The effect of fluoxetine hydrochloride in expression of neuropeptide Y of hypothalamus in depression mice model under chronic stress

结论：盐酸氟西汀+激素替代治疗对女性更年期抑郁症疗效较好，尤其对于中、重度抑郁者，是值得推荐的治疗方法。

Conclusions : Fluoxetine combination with hormone is better to cure woman menopause depression , especially for the severe patients .

目的探讨盐酸氟西汀对卒中后病理性哭笑的治疗作用。

Objective To investigate the efficacy of fluoxetine hydrochloride ( FXT ) for patients with poststroke pathological laughing and crying .

盐酸氟西汀联合激素与单纯激素补充治疗绝经期抑郁症的疗效比较

Comparison of the effect of fluoxetine combined with hormone replacement therapy ( HRT ) and single HRT in treating menopausal depression