酪氨酸激酶

抗Gleevec（STI-571）耐受的Bcr-Abl蛋白酪氨酸激酶抑制剂研究进展

Research development of inhibitors against gleevec ( STI-571 ) - resistant Bcr-Abl protien tyrosine kinase

研究人员在非小细胞肺癌病人身上确定了在体细胞EGFR酪氨酸激酶的突变，以EGFR为靶点的分子靶向治疗在NSCLC的治疗中日渐突出。

Researchers in NSCLC patients in somatic cells determine the epidermal growth factor receptor tyrosine kinase domain of somatic protein-altering mutations . The target molecular target therapy about EGFR in non-small cell lung cancer treatment came out gradually .

酪氨酸激酶受体B及其配体脑源性神经营养因子水平对神经母细胞瘤耐药的影响

Effects of tyrosine kinase receptor B and brain-derived neurotrophic factor on chemoresistance in neuroblastoma

先天性巨结肠神经营养因子-3、酪氨酸激酶C的表达及其意义

Expression of neurotrophin 3 and tyrosine kinase C in Hirschsprung 's disease and its significance

溶血性磷脂酰胆碱诱导血小板活化及蛋白质酪氨酸激酶和蛋白激酶C的作用

Lysophosphatidylcholine induced platelet activation and the role of protein tyrosine kinase and protein kinase C

酪氨酸激酶C与涎腺腺样囊性癌嗜颅神经侵袭的关系

The relationship between tyrosine kinase C and cranial perineural invasion in salivary adenoid cystic carcinoma

大鼠局灶脑缺血酪氨酸激酶B表达图像分析

The picture analysis of expression of tyrosine kinase B after focal cerebral ischemia in rats

涎腺腺样囊性癌中脑源性神经营养因子及酪氨酸激酶B的表达及意义

Expressions and Significance of BDNF and TrkB in Salivary Adenoid Cystic Carcinoma ; a salivary gland

子宫内膜肿瘤；脾酪氨酸激酶；基因，肿瘤抑制；DNA甲基化。

Endometrial neoplasms ; Spleen tyrosine kinase ; Gene , tumor suppressor ; DNA methylation .

免疫组化法观察大脑中动脉闭塞大鼠脑内酪氨酸激酶受体B的表达。

The expression of tyrosine kinase receptor B in the brain of MCAO rats was observed by immunohistochemical method .

表皮生长因子受体（EpidermalGrowthFactor，EGFR）是酪氨酸激酶型受体家族的成员。

Epidermal Growth Factor Receptor ( EGFR ) is an important RTK family member .

详细介绍了VEGF受体酪氨酸激酶抑制剂的研究进展。

The inhibitor of VEGF receptor tyrosine kinase was introduced in detail .

VEGF家族的受体均为酪氨酸激酶受体。

The recipients of VEGF family members are all tyrosine kinase recipients .

酪氨酸激酶受体KIT在肺癌中的表达及其意义

Expression and significance of tyrosine kinase receptor KIT in lung tumors

中药复方制剂对大脑中动脉闭塞大鼠脑酪氨酸激酶受体B表达的影响

Effect of Chinese herb prescription on the expression of tyrosine kinase receptor B in the brain of rats after middle cerebral artery occlusion

酪氨酸激酶型受体、G蛋白偶联受体和离子通道型受体是细胞表面三类主要受体。

Receptor tyrosine kinases ( RTK ), G protein-coupled receptors ( GPCR ) and ion channel receptors are main cell surface receptors .

甲磺酸伊马替尼是一种蛋白质酪氨酸激酶抑制剂，用于治疗Ph染色体阳性慢性粒细胞白血病和恶性胃肠道间质肿瘤。

Imatinib mesilate is a protein-tyrosine kinase inhibitor approved for the treatment of Philadelphia chromosome-positive chronic myelogenous leukemia and malignant gastrointestinal stromal tumors .

以EGFR家族受体酪氨酸激酶为靶点的抗肿瘤治疗研究进展

Advances in anti-tumor therapy targeting the EGFR family of receptor tyrosine kinases

Fms样酪氨酸激酶抑制剂治疗急性髓性白血病的新进展

Progress of treatment with Fms-like receptor tyrosine kinase-3 inhibitors for acute myelogenous leukemia

采用ELISA方法在分子水平检测AL68系列各活性化合物对EGFR酪氨酸激酶磷酸化的影响。

The effect of active compounds on EGFR tyrosine kinases phosphorylation was determined by ELISA assay .

抑制Src酪氨酸激酶对非小细胞肺癌细胞增殖的影响

Effect of inhibition of Src tyrosine kinase on cell proliferation of NSCLC

目前，已有几种EGFR酪氨酸激酶抑制剂进入了临床试验。本文对几种EGFR酪氨酸激酶小分子抑制剂在肿瘤治疗中的研究进展做一综述。

Currently , several EGFR tyrosine kinase inhibitors are in clinical trial stage .

EGFR突变与非小细胞肺癌酪氨酸激酶抑制剂靶向治疗

EGFR mutations and targeted therapy with tyrosine kinases inhibitors in non-small cell lung cancer

幽门螺杆菌依赖蛋白酪氨酸激酶途径诱导胃上皮细胞分泌IL-8

Helicobacter pylori-induced interleukin 8 secretion by gastric epithelial cells its relation to protein tyrosine kinase activation

蛋白酪氨酸激酶（proteintyrosinekinases，PTK）是细胞信号转导过程中极为重要的物质，具有多种细胞功能。

Protein tyrosine kinases with a variety of cell functions are extremely important materials in signal transduction .

PCR-SSCP法检测先天性巨结肠酪氨酸激酶受体基因突变

Detection of RET gene mutations in Hirschsprung disease by PCR-SSCP method

根据HER2/neu酪氨酸激酶ATP结合区的空间结构，搜索数据库，找出候选化合物；

To search database and pick up candidate compounds based 3D structure of HER2 / neu tyrosine kinase domain .

外源性绿色荧光蛋白和蛋白酪氨酸激酶受体B基因在大鼠骨髓源性神经干细胞内稳定表达的检测特征

Detection characteristics of the stable expression of recombinant plasmid enhanced green fluorescent protein-C 2-protein tyrosine kinase B gene in the neural stem cells derived from the bone marrow stromal cells of rats

许多研究表明，抑制EGFR酪氨酸激酶活性，可抑制肿瘤生长。

Many investigations have indicated that tumor growth can be suppressed by inhibiting EGFR tyrosine kinase activity .

评价轻度和重度先兆子痫患者胎盘生长因子及可溶型Fms样酪氨酸激酶1受体水平

Evaluation of placenta growth factor and soluble Fms-like tyrosine kinase 1 receptor levels in mild and severe preeclampsia