吸收促进剂

聚乙二醇1000维生素E琥珀酸酯（TPGS）是维生素E的水溶性衍生物，在国外现已广泛应用于制剂研究中，作为增溶剂、吸收促进剂、乳化剂、增塑剂以及脂溶性药物传递系统的载体。

Alpha-tocopherol polyethylene glycol 1000 succinate ( TPGS ), a water-soluble derivative of natural-source vitamin E , has been extensively applied at abroad as a pharmaceutical excipient , such as solubilizing agent , absorption enhancer , emulsifier , plasticizer and vehicle for controlled drug delivery application .

复合吸收促进剂对葛根素肠吸收及毒性的影响

Effect of multi-combination absorption enhancer on puerarin intestinal absorption and its toxicity

方法：在正常大鼠小肠分别给予含与不含吸收促进剂DOC的INSPLANP后，观察降血糖效果。

METHODS : After Ins-PLA-NP that contained or did not contain DOC was administered to small intestine of normal rats , the hypoglycemic effect was observed .

结论：CGRP可以用于鼻腔给药，其吸收促进剂初步确定为4%MDβCD。

Conclusion : CGRP can be used as a drug for the nasal absorption . 4 % MD β CD wes initially defined as accelerating absorption agent of nasal absorption preparation for CGRP .

Caco-2细胞转运试验结果显示：与对照组相比，六种吸收促进剂均可显著增加胶原酶的转运效率（P0.05），但促吸收效果依吸收促进剂的不同而有所差别。

The results of transport assay on Caco-2 cells demonstrated that compared with the control group , the absorption enhancers all significantly increased the absorption of collagenase ( P0.05 ), although the promotion degrees were various .

Unigene的片剂使用肠道大衣，蛋白酶抑制剂和吸收促进剂，以口头提供的多肽和蛋白质。

Unigene 's tablet formulations use an enteric coat , protease inhibitors , and absorption enhancers to deliver peptides and proteins orally .

采用Carbopol940作为凝胶基质，Azone和丙二醇为透皮吸收促进剂，用均匀实验设计，以芍药苷和绿原酸的累积释放百分率为指标，优选处方基质及透皮吸收促进剂的配比。

Carbopol 940 was used as the gel matrix , Azone and propylene glycol as penetration enhancer . With the Uniform design , regarding the cumulative release amount of Paeoniflorin and Chlorogenic acid as index , the optimise prescription matrices was selected .

透皮吸收促进剂应用及研究的新进展

New Development of Application and Research of Transdermal Penetration Enhancers

中药透皮吸收促进剂的研究与发展

Research and development of penetration enhancer of Chinese materia medica

5种吸收促进剂对胰岛素肠道吸收的影响

Effects of five absorption enhancers on intestinal absorption of insulin

7种吸收促进剂的鼻黏膜毒性及评价方法

Influence of seven absorption enhancers on nasal mucosa & assessment of toxicity

几种吸收促进剂和酶抑制剂对胰岛素结肠吸收的影响

Effects of Absorption Enhancers and Protease Inhibitors on Colonic Delivery of Insulin

柠檬酸和牛胆酸钠作为吸收促进剂将血清内干扰素浓度提高了30～50倍。

The serum concentration increased by about 30-50 times with the absorption promoters .

肽类药物的口服吸收促进剂氯化N-三甲基壳聚糖

Recent Development of N-trimethyl Chitosan Chloride as an Absorption Enhancer of Oral Peptide Drugs

不同吸收促进剂对大鼠口腔胰岛素吸收作用的影响

Effects of the various absorption enhancers on the buccal absorption of insulin in rats

我院2003～2005年钙制剂及钙吸收促进剂利用分析

Utilization of Calcium Products and Calcium Absorption Enhancers

复合型透皮吸收促进剂对黄芩苷透皮吸收的影响

Study on the effects of compound transdermal enhancers on the transdermal kinetics of baicalin

目的：介绍桉叶油透皮吸收促进剂研究进展。

OBJECTIVE : Introduce the development of the eucalyptus oil as a transdermal absorption enhancer .

透皮吸收促进剂对大黄中蒽醌类有效成分透皮吸收的影响

Effects of Skin Penetration Enhancers on the Transdermal Absorption of Effective Components in Anthraquinones from Rhubard

丁卡因、利多卡因联合透皮吸收促进剂对静脉留置针穿刺镇痛的临床研究

Clinical study of venous indwelling needle analgesia by Tetracaine , Lidocaine combined with Transdermal absorption enhancers

肠吸收促进剂可改善肠粘膜透过能力低药物的口服生物利用度。

Intestinal absorption enhancers are used to improve oral bioavailability of those compounds with poor membrane permeability .

肠吸收促进剂的研究进展

Development of Intestinal Absorption Enhancers

目的：研究复合型透皮吸收促进剂对黄芩苷体外渗透动力学的影响。

OBJECTIVE To study the effect of penetration enhancers on the permeability of papaverine gel through skin .

目的：对降钙素基因相关肽鼻腔给药制剂的吸收促进剂进行初选。

Objective : Primarily to select absorption accelerating agent of nasal absorption preparation for calcitonin gene related peptide .

吸收促进剂对鼻腔黏膜毒性影响：1%去氧胆酸钠、1%氮酮和1%甘草酸二钾毒性大；

1 % sodium deoxycholate , 1 % azone and 1 % dipotassium glycyrrhizinate had serious nasal toxicity ;

综述了近年来肠道、皮肤、鼻腔、眼、呼吸道、直肠等制剂中的药物吸收促进剂毒性的研究概况。

Effects of absorption promoter on drug permeability in one-way slow release of compound tinidazol from the drug film ;

目的：研究不同的吸收促进剂及酶抑制剂对胰岛素透过口腔黏膜的影响。

To study the effects of various absorption enhancers and enzyme inhibitors on insulin permeation in vitro and in vivo .

方法用0.5%去氧胆酸钠作吸收促进剂的鼻喷胰岛素治疗8例Ⅱ型糖尿病病人。

Methods Intranasal spray insulin containing 0.5 % sodium deoxycholate as an absorptive promoter was used in 8 NIDDM patients .

本文综述了肠吸收促进剂研究的实验方法、制剂及生理因素对其促吸收作用的影响、安全性问题以及近年重点研究的促进剂类型。

The experiments , formulation , physiologic variables and toxicity problem are reviewed to exemplify the use of several absorption enhancers .

结论：初步确定降钙素基因相关肽鼻腔给药的吸收促进剂为4%二甲倍他环糊精。

Conclusion : 4 % MD β CD was initially defined as accelerating absorption agent of nasal absorption preparation for CGRP .