神经毒素

B型肉毒神经毒素基因的PCR检测

Detection of Clostridium botulinum type B neurotoxin gene by polymerase chain reaction

目的：建立梭菌属神经毒素基因快速鉴定和分型的PCR方法。

Objective : To establish a PCR method for gene identification and genotyping of clostridial neurotoxin .

多重聚合酶链式反应检测C、D型肉毒神经毒素基因

Multiplex polymerase chain reaction for detection of type C and D

两个东亚钳蝎抗哺乳动物神经毒素的cDNA序列

CDNA Sequences of Two Anti mammals Neurotoxins from Scorpion Buthus martensii Karsch

触手总RNA中分离出多个神经毒素新基因。

Several new neurotoxin genes were identified .

利用RT－PCR技术从中华眼镜蛇毒腺组织中成功地克隆了短链神经毒素CDNA。

A novel short-chain neurotoxin cDNA was cloned from Chinese cobra venom by RT-PCR .

此外，还克隆到该神经毒素缺失前体cDNA。

Furthermore , the cDNA encoding the deletion precursor of α bungarotoxin was also cloned .

E型肉毒神经毒素（BoNT）基因序列分析及其B细胞表位预测

Gene sequence analysis of Clostridium botulinum neurotoxin serotype E and prediction of related B cell epitopes

南美响尾蛇神经毒素对人肺腺癌A549细胞生长抑制作用研究

Suppression Effects of Crotoxin on Human Lung Adenocarcinoma Cell Line A549

南美响尾蛇神经毒素联合吉非替尼对人肺腺癌A549细胞的作用

Effects of Crotoxin Combined with Iressa on A549 Cells

东亚马氏钳蝎部分纯化的神经毒素对GH＿3细胞钠电流的影响

Effects of Partially Purified Neurotoxins from Scorpion Buthus Martensii on the Sodium Currents of GH_3 Cells

昆虫神经毒素的研究：DDT对美洲（虫非）蠊L-酪氨酸脱羧酶的诱导作用

Studies on insect neurotoxin : DDT induction of tyrosine decarboxylase in the American cockroach

由此可见，该PCR扩增系统用于A型肉毒神经毒素基因的检测具有灵敏度高，特异性强等特点，为A型肉毒梭菌的鉴定及肉毒中毒的快速诊断提供了一种新的手段。

Therefore , it suggests that the PCR system is specific and sensitive for identification of Clostridium botulinum type A and rapid diagnosis of type A botulism .

自由基在神经毒素MPTP致帕金森病中的作用机制

Mechanisms of Free Radical Causes Parkinson Disease among the Neurotoxic MPTP

本工作为进一步研究中介蝮磷脂酶A2神经毒素的分子进化及作用机理奠定了理论基础。

This work may therefore establish the theoretical foundation for the further study of molecular evolution and molecular mechanism of envenomation .

一种分离提纯眼镜蛇（Najanajaatra）神经毒素的简便方法

A simple method for isolation and purification of cobra neurotoxin from the venom of Naja naja atra

[方法]用复乳化-溶剂挥发法制备了神经毒素（α-cobro-neurotoxin，CNT）PLGA纳米粒（CNT-PLGA-NP）；

[ Method ] CNT-PLGA-NP was prepared by double emulsification solvent evaporation .

目的：探讨神经毒素（α-cobrotoxin，Nt）不同给药途径对镇痛作用的差异，寻找神经毒素最佳给药途径。

Objective : To explore the analgesia effect of different administration pathway of α - cobrotoxin and look for the best pathway of α - cobrotoxin .

MAOB基因敲除小鼠对神经毒素1-甲基-4-苯基-1,2,3,6-四羟嘧啶（MPTP）具有耐受性。

MAOB gene knock-out mice are resistant to the neurotoxin , 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine .

神经毒素的LD50为1.11mg/kg。

The median lethal dose of neurotoxin was 1.11mg/kg by calculating .

目的探讨神经毒素兴奋性氨基酸（EAA）和神经肽在脊髓损伤中的作用。

Objective To elucidate the effect of neurotoxin , excitatory amino acid and neuropeptide on spinal cord injury post trauma .

该神经毒素在1.25mg／kg（i.p.）

When compared with pethidine hydrochloride ( 30mg / kg ), the neurotoxin in a dose of 1.25mg / kg ( i.p. )

肉毒神经毒素（Botulinumneurotoxin，BoNT）是由厌氧的肉毒梭状芽孢杆菌产生的一种烈性蛋白毒素。

Botulinum neurotoxin ( BoNT ), which is the most toxic protein , is produced as a potent toxin by the anaerobic clostridium botulinum .

眼镜蛇（Najanajaatra）神经毒素与心脏毒素分离纯化研究进展产生神经毒液的蛇是非洲树眼镜蛇和眼镜蛇。

Separation and Purification of Neurotoxins and Cardiotoxins from Cobra Venom ( Naja naja atra ) The makers of the nerve poison include the mambas and cobras .

神经毒素ECMA对家鸽视网膜神经节单元反应特性的影响

Effects of ECMA ( ethylcholine mustard aziridinium ion ) on the response properties of the retinal ganglion units in pigeon

电压门控钠通道（VGSC）是许多天然生物神经毒素特异作用的靶受体。

Voltage gated Na + channel ( VGSC ) is the target of numerous natural neurotoxins .

本实验运用受体放射自显影术观察神经毒素甲基-苯基-四氢吡啶（MPTP）在大鼠脑内的分布，并运用亚细胞成份分离技术研究MPTP在小鼠脑亚细胞成分中的分布。

The distribution of methyl-phenyl-tetrahydropyridine ( MPTP ), a neurotoxin , in rat brain and organellae of mouse brain was studied by receptor autoradiography and subcellular fractionation respectively .

为了解决眼镜蛇神经毒素（CNT）临床应用时起效慢、镇痛效果不太显著的问题，本课题将PEG修饰技术应用于CNT。

In order to solve the problems which Cobra Neurotoxin ( CNT ) encountered in clinical applications ( such as slow action and unremarkable analgesic effect ), this PEG modification technology was used on CNT .

表达昆虫特异性神经毒素AaIT基因的转基因烟草的抗虫性

Insect-resistant Tobacco Plants Expressing Insect-specific Neurotoxin AaIT

结果提示，BmKAS类蝎神经毒素在哺乳动物和昆虫兴奋性细胞膜上存在着特异的靶受体。

It indicates that there are special target receptors for BmK AS type scorpion neurotoxins on both mammal and insect excitable cell membranes .