病理过程

结论IL-8、TNF系统参与原发性甲减的发病过程，参与自身免疫反应的免疫病理过程。

Conclusion IL-8 , TNF participate in hypothyroidism pathogenic process and the autoimmune pathological process .

结论NF-κB和IL-6水平在脑损伤的炎性病理过程中起重要作用。

Conclusions NF - κ B and IL-6 may play an important role in inflammation pathological process of cerebral ischemia-reperfusion injury .

前列腺素E1在眼球前段穿破伤病理过程中的作用

Experimental study on prostaglandin E_1 in penetrating ocular trauma of the anterior segment

组织蛋白酶B是溶酶体内半胱氨酸内切蛋白水解酶，作用广泛，参与机体多种生理、病理过程。

Physiology Function Analysis of Lysosomal Cysteine Proteases Cathepsin B is a lysosomal cysteine endoproteinase which participates in many physiological and pathological events .

一氧化碳（CO）作为新型递质，参与中枢神经系统的多种生理功能和病理过程。

As a new transmitter , Carbon monoxide is also involved in many process of physiology and pathophysiology .

结论：TNF可能参与冠心病、高血压的病理过程。

Conclusion : TNF may be involved in the pathological processes of both CHD and hypertension .

研究显示，DC广泛参与机体免疫、炎症、肿瘤免疫、移植排斥、应急反应等生理及病理过程。

DC participate immunization , inflammation , tumor immunity , graft rejection , emergency response and other physiological and pathological processes .

结论：VEGF可能在慢性泪囊炎粘膜增生的病理过程中发挥重要的作用。

CONCLUSION : VEGF may play an important role in hyperplasia of inflammatory mucosa of lacrimal sac .

在脑缺血再灌注过程中，产生氧自由基等毒性产物攻击DNA和DNA损伤修复系统，两者共同参与脑缺血再灌注损伤的病理过程，保护DNA通常可以减轻脑缺血再灌注损伤。

During cerebral ischemia-reperfusion , harmful products , especially oxygen free radicals , attacked DNA and DNA repairing system , which influenced cerebral ischemia-reperfusion injury .

结论：脑缺血后DC参与了脑缺血病理过程，表达细胞因子产生免疫效应。

Conclusion : DCs may play roles in cerebral ischemic proceses and participate in the injury process by producing cytokines after cerebral ischemia .

胰腺损伤是AP肺损伤病理过程的决定性始动环节。

Pancreas acinar cell injury may be the determinant initial events of acute pancreatitis-associated lung injury .

目的用基因芯片技术研究阿尔茨海默病（Alzheimer'SDisease，AD）患者与健康老人之间基因表达谱差异，筛选与AD病理过程相关联的基因。

Objective To study the gene expression difference between patients with Alzheimer 's disease and healthy elders , and to further search for the associated genes .

抗氧化酶以SOD活性改变对细胞发光影响最大，提示活性氧代谢失衡和抗氧化酶防御系统功能低下在肿瘤病因学或病理过程中有着重要意义。

It is suggested that active oxygen species and the enzymes play an important role in the etiology pathogenesis of cancer .

阿片依赖病理过程中NMDA受体与阿片受体的相互作用及分子机制

Cross-talk and molecular mechanisms between NMDA receptor and opioid receptor in opioid dependence

已经有大量的实验描述了胰岛素抵抗（InsulinResistance，IR）的病理过程中TNF-α的作用。

A large number of experiments have described the role TNF - α acts in insulin resistance ( Insulin resistance , IR ) of the pathological process .

结论RA涉及多环节的病理过程，基因芯片技术有利于进一步揭示RA分子机制，发现新的治疗靶标。

Conclusion These findings are expected to improve the understanding of the molecular mechanisms and the identification of therapeutic targets .

另一方面，NMDA受体功能异常也参与了多种神经精神疾病的病理过程。

On the other hand , NMDA receptor is also involved in many neuronal degeneration diseases .

目的观察大鼠视神经挤压伤后基质金属蛋白酶（matrixmetalloproteinase，MMP）-2和-9的表达，探讨MMP-2（明胶酶A）和MMP-9（明胶酶B）是否参与视神经损伤后的修复病理过程。

Objective To investigate the expression of matrix metalloproteinase ( MMP ) - 2 and MMP-9 in rats ′ optical nerves after extrusion wound .

结论NO、NOS、VitE、TAO在银屑病的病理过程中可能具有一定作用。

Conclusion NO , NOS , VitE and TAO probably play an important role in pathogenesis of psoriasis .

兴奋性氨基酸受体N-甲基-D-门冬氨酸（NMDA）受体在脑缺血损伤的病理过程中起重要作用。

N-methyl-D-aspartate ( NMDA ) receptors play an important role in the pathological processes of ischemic neuron injury .

结论ET与IGF-Ⅰ相互作用促进血管平滑肌增殖，两者可能共同参与了球囊血管成形术后再狭窄的病理过程。

Conclusion ET and IGF - ⅰ as a stimulator of vascular smooth muscle cells proliferation might participate in the pathological process of restenosis after balloon angioplasty .

PDGF-B参与了肝纤维化的病理过程。

PDGF - B participated in the process of hepatic fibrosis .

动脉粥样硬化（atherosclerosis，AS）的发生发展是一长期的综合性的病理过程，好发于动脉血管分支处、弯曲处以及搭桥血管连接处。

Atherosclerosis is a chronic and synthetic disease . Atherosclerotic lesions are prone to develop at bifurcations , bends and junction of bypass points in vessels .

目的细胞外信号调节激酶（ERK）与细胞生长，分化，增殖等生理病理过程有密切关系。

Objective Extracellular signal-regulated kinase ( ERK ) is closely related to cellular growth , differentiation and proliferation .

结论ER、PR和ACTH可能在少年乳腺纤维腺瘤的发生或病理过程中起着重要的作用。

Conclusion ER , PR and ACTH may be the important pathogeny for the occurrence or in pathological process of breast fibroadenoma of juvenility .

结论：HSP70、iNOS、TNF-α及IL-β参与了外伤性脑水肿的病理过程。

Conclusion : HSP 70 , iNOS , TNF - α and IL-1 β are involved in contusion cerebral edema .

DR的发病是一个复杂的、与多因素相关的病理过程，DR的基本病理改变包括：①周细胞选择性的丢失；

The outbreak of DR is a complicated pathologic process related with many factors . The basic pathologic changes in DR include :① the choice lost of round cells ;

结论急性低压缺氧可引起老龄大鼠大脑皮质和丘脑中ET、NO含量明显升高以及大脑皮质血管内皮细胞和神经细胞明显损伤，ET、NO可能参与了缺氧性脑损害的病理过程。

Conclusion It is suggested that , the increase of ET and NO contents of cerebral cortex and thalamus may participate in the pathogenesis of hypoxia brain injury in old rats .

一氧化氮（nitrooxide，NO）、c-Fos蛋白、内源性阿片肽都表达于神经系统内，参与机体炎性疼痛的病理过程。

Nitro oxide ( NO )、 c-Fos protein and endogenous opioid peptide are present in the nervous system and involved in the pathological process of inflammatory pain .

目的探讨LIM辐射对血管RS病理过程的影响，以评价LIM辐射防治RS的可能性。

Objective Discuss the irradiating effect of LIM to the pathological process of blood vessel RS and assess the probability of LIM irradiation to prevent RS.