头孢吡肟

结论头孢吡肟在控制VAP细菌感染、提高细胞免疫功能和减少真菌发生方面具有一定的作用。

CONCLUSIONS Cefepime controlled bacterium of VAP , increased cellular immunity and decreased fungus .

结果头孢吡肟治疗后，细菌转阴率为81.25%，CD3，CD4明显上升。

RESULTS After treatment of cefepime , the rate of bacterium vanishment was 81.25 % and CD 3 and CD 4 rised .

HPLC法测定盐酸头孢吡肟中的有机残留量N-甲基吡咯烷

Determination the contents of residual volatile organic solvents of N-Methyl-pyrrolidine in Cefepime dihydrochloride by HPLC

头孢吡肟血药浓度HPLC测定方法建立及临床应用

Development of a HPLC Method for the Determination of Cefepime in Plasma and Its Clinical Application

采用HPLC法测定注射用盐酸头孢吡肟中L-精氨酸的含量。

HPLC method for determination of arginine hydrochloride oral solution was established .

盐酸头孢吡肟及其注射剂中N-甲基吡咯烷GC测定的方法学研究

Methodology Study on Determination of N-Methyl Pyrrolidine in Cefepime Hydrochloride and Its Injections by GC

结果盐酸头孢吡肟与其中间体、降解产物及E异构体分离良好。

RESULTS The method was proved to be selective for the separation of cefepime hydrochloride , its degradation products and E-isomer .

方法：将65例慢阻肺伴下呼吸道感染患者随机分为两组，在常规治疗的基础上，治疗组32例，采用头孢吡肟2g，静脉滴注，每12h1次；

Methods : 65 patients were randomized into two groups .

目的：观察头孢吡肟对重症监护病房（ICU）院内感染细菌的体外抗菌活性。

AIM : To observe antibacterial activity of cefepime to bacteria of intensive care unit ( ICU ) nosocomial infection in vitro .

肠杆菌属对头孢吡肟、头孢他啶、环丙沙星（CIP）及阿米卡星介于62%～74%；

Enterobacteriaceae to FEP , CAZ , CIP , AMK was from 62 % to 74 % ;

联合应用抗生素对中性粒细胞减少期感染的经验性治疗结论：在ICU院内感染流行病学监测指导下，头孢吡肟可作为经验性治疗院内细菌感染的首选抗生素之一。

Antibiotic Combined Therapy as an Empirical Treatment for Febrile Patients with Neutropenia CONCLUSION : Cefepime is an effective antibacterial agent for nosocomial infection .

到那时候，FDA将通知医疗供应商考虑安全标签和荟萃分析中描述的头孢吡肟疗法的风险获益。

Until that time , healthcare providers are advised to consider the risks and benefits of cefepime therapy as described in the safety labeling and the meta-analysis .

采用高效液相色谱/串联质谱技术建立了快速鉴定Z型盐酸头孢吡肟原料药中E型异构体杂质的新方法。

A sensitive and specific identification method of E isomer impurity in raw drug of Z cefepime dihydrochloride was established with high performance liquid chromatography / tandem-time of flight ( HPLC / ( Q-TOF )) mass spectrometry technology .

亚胺培南、头孢吡肟、头孢曲松和氨曲南对阴沟肠杆菌AmpC酶的诱导性研究南亚和东南亚区域局

Comparative Induction of Imipenem , Cefepime , Ceftriaxone and Aztreonam to Enterobacter Cloacae AmpC β - lactamase ; Regional Bureau for South and South-East Asia

治疗尿道感染头孢吡肟每次1g，2次／d，头孢他啶每次1g.3次／d；

Administrative scheme : To treat urethra infection , Cefepime 1g every time , 2 times daily , Ceftazidime 1 g every time , 3 times daily ;

在ICU，鲍曼不动杆菌对亚胺培南暂无耐药性，其次对头孢吡肟、替卡西林/克拉维酸、哌拉西林/三唑巴坦和阿米卡星的耐药率分别为18%、29%、35%和38%。

The Acinetobacter baumannii have no drug resistance to imipenem in ICU at this time , The drug resistant rate of A baumannii to Cefepime , ticarcillin / clav , piperacillin / tazobactan , and amikacin is 18 % , 29 % , 35 % , and 38 % respectively .

结果：各温度下头孢吡肟百分含量的对数（lgC）与时间（t）具有线性关系，符合一级动力学反应；

RESULTS : There was a linearity between the cefepime contents in the solutions in logarithm ( lg C ) and time ( t ) at each temperature . It responded to the first order kinetic reaction .

慢性肾衰竭患者应用头孢吡肟出现神经毒性反应

Neurotoxicity induced by cefepime use in patients with chronic renal failure

头孢吡肟等抗生素对革兰阴性杆菌体外药物敏感实验结果分析

Antimicrobial activities of cefepime aga in st gram-negative bacteria in vitro

高效液相色谱法检测设备淋洗液中盐酸头孢吡肟残留含量注射用盐酸头孢吡肟与4种常用输液配伍的稳定性研究

Stability study of Cefepime Hydrochloride Injection combined with four common used liquids

头孢吡肟治疗老年人院内获得性呼吸道感染31例

Cefepime in treating hospital acquired respiratory tract infections in 31 elderly patients

头孢吡肟静注致严重过敏反应2例

Serious allergic reactions in connection with intravenous cefepime : 2 case reports

头孢吡肟治疗危重患者医院获得性感染40例

Cefepime for the treatment of 40 risk-severe patients with nosocomial acquired infection

气相色谱测定盐酸头孢吡肟中残留甲醇、乙醇和丙酮的含量

Determination of residual methanol , ethanol and acetone in Cefepime by GC

头孢吡肟治疗院内获得性肺炎疗效评价

Observation of the therapeutic effcet of cefepime in the treatment of nosocomial pneumonia

头孢吡肟注射液在汉族健康人体的药物代谢动力学

Pharmacokinetics of cefepime injection in Han healthy Chinese volunteers

头孢吡肟对重症监护病房院内感染细菌的体外抗菌活性研究

In vitro antibacterial activity of cefepime to bacteria of intensive care unit nosocomial infection

头孢吡肟治疗儿童呼吸道中重度细菌性感染的疗效观察

Clinical effect and safety of cefepime on children with moderate and severe respiratory infection

头孢吡肟在老年重症医院获得性肺炎治疗中的价值

The value of Cefepime for therapy on aged patients with severe hospital acquired pneumonia

注射用头孢吡肟不良反应相关因素分析

Analysis of factors related to cefepime adverse reaction