头孢

C3-氯代头孢烯酸类衍生物头孢克洛2001年在美国的销售额超过8千万美元，位居抗生素类药物销售额第二位。分期付款买卖制度研究

In 2001 , the sales of On Installment Selling System

双波长紫外分光光度法考察头孢美唑与维生素C配伍的稳定性实验

Study on the compatible stability of cefmetazole with vitamin C by dual wavelength spectrophotometry

头孢克肟的合成路线有两条：7ACA工艺和脱乙酰头孢菌素C工艺。

There are two synthetic processes of cefixime : 7-ACA process and deacetylcephalosporin C process .

含量、pH值均无明显变化。结论：头孢曲松钠可以与奥哨唑氯化钠注射液配伍。

Conclusion : ceftriaxone sodium is compatible with ornidazole and sodium chloride injection .

固定化巨大芽孢杆菌青霉素G酰化酶酶促合成头孢氨苄的研究

Studies on enzymatic synthesis of cephalexin by immobilized penicillin G acylase from Bacillus megaterium

HPLC法监控头孢拉定生产中的酰化反应与萃取操作

Monitoring the acylating reaction and extraction process of cefradine by HPLC

HPLC法测定头孢硫脒大鼠体内分布浓度及其药动学研究

Determination of cefathiamidine in rat tissue distribution and pharmacokinetic study by HPLC

头孢泊肟酯口服干混悬剂中苯甲酸钠的HPLC测定

Determination of Sodium Benzoate in Cefpodoxime Proxetil for Oral Suspension by HPLC

HPLC测定头孢唑啉和头孢他啶在人椎间盘髓核的分布

Determination of Cefazolin and Ceftazidime Distribution in Human Nucleus Pulpous by HPLC

柱前衍生HPLC法同时测定注射用头孢拉定原料中的3种成分

Determination of Three Components in Cefradine for Injection with Precolumn Derivatization HPLC

目的：建立了测定盐酸头孢替安含量的HPLC法。

Objective : To establish a HPLC method for Determination of Cefotiam Hydrochloride .

HPLC法测定头孢氨苄胶囊的含量头孢氨苄片剂及胶囊剂溶出度考察

DETERMINATION OF CEPHALEXIN CAPSULES BY HPLC Dissolution rates of cephalexin tablets and capsules

建立一种HPLC法快速测定头孢拉定血清浓度。

To establish a simple HPLC column switching method for measuring cefradine in human serum .

头孢曲松钠预防LC术后感染的临床研究

Clinical study of ceftriaxone sodium on prevention of postoperative infection of laparoscopic cholecystectomy

结果盐酸头孢吡肟与其中间体、降解产物及E异构体分离良好。

RESULTS The method was proved to be selective for the separation of cefepime hydrochloride , its degradation products and E-isomer .

方法用HPLC法测定头孢唑啉钠眼膏剂的含量并观察临床疗效。

Methods To determine the content of cefazolin sodium by HPLC and Observing the clinical effect of Cefazolin Sodium Eye Ointment .

结果在0～6h内，溶液外观、pH值和紫外吸收光谱基本不变化，头孢匹胺与奥硝唑的含量没有明显的变化。

Result There were no evident changes in apparent , PH , content and absorption curves within 6h .

另对C厂头孢羟氨苄胶囊同时采用桨法和转篮法进行溶出度考察，并将结果做t检验。

Besides , the dissolution tests were conducted on cefadroxil capsules that from manufacturer C by oar method and baskets-rotating methods simultaneously and the results of which were subjected to t-tests .

本文对15名新生儿进行了单次静脉滴注头孢拉定50mg／kg后的药物动力学研究，并对8名新生儿进行了尿药浓度测定。

The pharmacokinetics after single intravenous injection of cephradine 50mg / lg was studied in 15 neonates .

结果头孢米诺钠与氨甲苯酸在配伍后8h内，含量及混合液pH值均无显著变化。

Results There was no evident variation in its content and pH during 8 h at 25 ℃ after compatibility .

头孢唑酮与TritonX-100缔合体系的相互作用

Interaction of Cephanone with Triton X - 100 Aggregates

用高效液相色谱法，测定健康男性志愿者8名，血清中2种头孢克罗胶囊（T药、R药）的药物浓度，进行相对生物利用度研究。

Relative bioavailability of two products of cefaclor capsules ( referred to as T and R ) in sera of eight healthy male volunteers were determined by high performance liquid chromato-graphy .

目的：研究受试制剂头孢克肟干混悬剂（A）、胶囊剂（B）和参比制剂（C，头孢克肟胶囊，世福素）的人体生物等效性。

OBJECTIVE : To study the bioequivalence of suspension formulation of cefixime ( A ), capsule formulation of ce-fixime ( B ) and reference preparation ( C : Cefixime Capsules or Cefspan ) in human body .

结果：①静滴头孢拉定后1d内出现血尿者10例，占83.33%；

Result : 1 ) The hematuria occured one day after cefradine given by intravenous infusion ( 83.33 % );

头孢噻甲羧肟、环丙沙星、亚胺培能对绿脓假单胞菌的MIC90分别为8、3、6μg／ml。

MIC90 for ceftazidime , Ciprofloxacin , and Imipenem against Pseudomonas aeruginosa was 8,3 and 6 μ g / ml , respectively .

179例肺、食管择期手术病人，麻醉诱导时，静脉注射头孢曲松1g。

179 patients were given 1g of ceftriaxone intravenously at induction of anesthesia .

方法采用现版的不同药典的相关HPLC法及HPLC-MS分析，研究头孢噻肟钠的完全杂质谱。

Methods The current HPLC methods in different pharmacopoeia and HPLC-MS analysis were performed to study on the complete impurity profile of Cefotaxime Sodium .

第三组117例，术前1d、手术日及术后1d共3d，每日2次头孢拉定1g静脉注射。

117 patients in group 3 were given Cephradine 1g b. i. d at the day before surgery , surgery day and the day after surgery .

体外抑菌试验结果表明：头孢噻呋对各种标准及临床菌株的MIC均较小；

The results of antimicrobial susceptibility in vitro showed that Ceftiofur was a broad-spectrum Cephalosporin with potent activity against all kinds of clinical and standard strains ;

高压液相色谱法测定PVC中DOP含量头孢拉定精氨酸中精氨酸的含量与有关物质在同一高压液相色谱条件下进行检测。

The Determination of DOP in PVC by HPLC A HPLC method was established for the determination of the Arginine and related substances in Cephradine for Injection simultaneous .