刺五加

黄芪、刺五加对儿童单纯性肾病肾上腺皮质功能低下的保护作用及其临床意义

Astragali and acanthopanax root for idiopathic nephrotic syndrome hypoadrenocorticism in children : the protection and clinical significance

目的：探讨刺五加叶皂甙（ASS）治疗糖尿病的作用机制。

Objective : To explore the therapeutic mechanism of manyprickle acanthopanax root saponin ( ASS ) in treating diabetes mellitus .

而刺五加苷E具有与之相同的药效学作用。

Eleutheroside E has the same pharmacodynamic efficacy as well .

结果表明，刺五加愈伤组织与其来源植株相比出现了DNA水平的变异。

The results indicated that there was genetic variation between callus and the original plant .

但是刺五加皂苷单体B对心肌缺血是否起到保护作用还不清楚，目前还一直未见报道。

But , It is not clear that Ciwujianoside-B ( Sb ) has protective effects on myocardial ischemia .

目的：建立刺五加注射液的HPLC指纹特征谱。

Objective : To establish the HPLC profile of Ciwujia Injection .

刺五加皂甙B对心室肌细胞膜ATP敏感性钾通道的作用

Effect of acanthopanax senticosides B on sarcolemmal ATP sensitive potassium channel of ventricular myocytes

刺五加注射液HPLC数字化指纹图谱研究

Study on the digitized HPLC fingerprints of Ciwujia injection

HPLC法测定黑龙江省不同地区刺五加紫丁香苷的含量

Syringin content of Acanthopanax senticosus samples in Heilongjiang different zones measuring by HPLC method

刺五加叶皂苷对心肌ATP敏感性钾通道的作用

Effects of acanthopanax senticosus saponins on myocardial ATP sensitive potassium channel

目的研究刺五加叶皂甙（ASS）对实验性Ⅱ型糖尿病大鼠胰岛素和C肽分泌作用影响。

Objective To study the effects of ASS on insulin and C-peptide in experimental NIDDM rats .

采用双侧颈总动脉结扎建立SD大鼠暂时性全脑缺血模型，手术后通过尾静脉注射刺五加注射液或生理盐水。

The temporary cerebral ischemia model was established through common carotid arteries occlusion .

刺五加注射液对脑出血大鼠血肿周围组织含水量、SOD、MDA水平的影响

Effects of Acanthopanax Senticosus on Brain Water Content , SOD and MDA after Intracerebral Hemorrhage in Rats

刺五加对老龄小鼠SOD活性和LPO含量的影响

Effects of acanthopanax senticosus on SOD activity and LPO level in the elderly mouse

结论：①刺五加注射液能提高Bcl-2蛋白表达，减少脑缺血区细胞凋亡的发生。

Conclusion : can increase the expression of bcl-2 and decrease the cell apoptosis at cerebral ischemia tissue .

刺五加注射液对人肺腺癌A549细胞增殖的抑制作用

Inhibitory effect of Acanthopanax senticosus injection on growth of human lung adenocarcinoma A549 cells

三氧化二砷与刺五加合用诱导HeLa细胞凋亡的实验研究

Experimental Study on the Apoptosis of HeLa Cells Induced by Arsenic Trioxide and acanthopanax senticosus

方法：本实验首先通过标Ⅱ导联方法观察了刺五加皂苷单体B对正常大鼠和异丙肾上腺素导致的急性心肌缺血大鼠心电图S-T段的影响。

Aim : We wil research that ciwujianoside-B protect against acute myocardial ischemia of rats caused by isoproterenol .

结论：结果提示刺五加复方口服液能增强冷暴露机体的能量代谢，增加超氧化物岐化酶（SOD）的活性，改善机体局部微循环功能，并有一定的抗疲劳作用。

Conclusion : AS compound may enhance energy metabolism , increase SOD activity , improve local micro-circulation and may have some anti-fatigue effect .

目的：探讨刺五加皂苷（ASS）对X射线照射小鼠抗辐射损伤的作用。

Objective To evaluate the protective effects of acanthopanax senticosus saponins ( ASS ) on mice with irradiation damage induced by X-rays .

刺五加注射液治疗组与模型组相应时间点比较有显著性差异（P0.01或P0.05）。

The expressions of ASI group had significant difference at the corresponding time point compared with model group ( P0.01 or P0.05 ) .

结论刺五加具有降低血浆ET-1、降低血小板表面活性、抑制血小板聚集和粘附、抗血栓形成的作用。

Conclusion Acanthopanax can decrease endothelin , reduce platelet surface activity and inhibit the platelet adhesiveness and aggregation .

组分C经过在紫外灯下定位及HPLC色谱分析，被鉴定为刺五加苷B即紫丁香苷。通过苯酚&硫酸法对养生酒进行了多糖含量的测定。

Component C was identified as syringin . through the UV lamp positioning and HPLC chromatographic analysis , and analysis the polysaccharides in the health wine by the phenol-sulfuric acid method .

刺五加叶皂甙对Ⅱ型糖尿病大鼠GLP-1和血糖分泌的影响

Effects of Ass Glp-1 and Blood Glucose in Experimental NIDDM Rats

目的观察刺五加叶皂苷（SS）急性血瘀模型大鼠血液流变学的影响。

Objective To study the effect of Acanthopanax senticosus saponins ( ASS ) on hemorheology in rat model of acute blood stasis .

刺五加果肉中脂溶性成分的GC-MS分析

Analysis of Liposoluble Components from the Pulp of Acanthopanax senticosus ( Rupr . et Maxim ) Harms by GC - MS

刺五加注射液可能通过降低TNF-α和ICAM-1的表达，并且促进TGF-β1升高发挥其神经保护作用。

ASI may play its neuroprotective role by reduce the expressions of TNF-a and ICAM-1 , and increase the expressions of TGF-pl.

刺五加（AcanthopanaxSenticosus）生理生态学特性的研究&1.展叶期

A Study on the Physiological Ecology Characters of Acanthopanax Senticosus ⅰ . Elongating stage of leaf

目的：研究刺五加叶皂苷（ASS）对麻醉犬器官血流及血管阻力的影响。方法：ASS按7.5、15.0、30.0mg。

Objective To study the effect of Acanthopanax senticosus saponins ( ASS ) on organ blood flow and vascular resistance in anesthetized dogs .

方法：采用无血清培养方式制备离体培养的ICR小鼠胎鼠脑皮层神经元衰老模型，从生化和形态方面观察刺五加皂甙对衰老条件下的神经元保护作用。

Methods : Aging model of serum free damage to cultured mice cortical neuronal cells were used .