利福霉素

利福霉素B发酵过程中巴比妥钠加量的优化

Optimization of Barbital Sodium Content during Fermentation of Rifamycin B

利福霉素B的提取工艺研究

Extraction process of rifamycin B from fermentation broth

体系pH值对利福霉素恶嗪环合反应的影响

Effect of System pH Value on the Rifamycin Oxazine Cyclization Reaction

利福霉素B的选育及其发酵的研究

Study of Rifamycin B Selection and Fermentation

HPLC法测定利福霉素钠注射液的有关物质

Determination of Related Substances of Rifamycin Sodium Injection by HPLC

利福霉素单克隆抗体的制备及竞争ELISA检测方法的建立

Preparation of McAbs against Rifamycin and Development of A Competitive ELISA Method

本文使用神经网络对历史数据进行处理，得到了利福霉素B培养基成份和发酵效价之间的关系；

In this paper , artificial neural network ( ANN ) was used to predict the relationship between the potency of rifamycin B and the fermentation medium minor error .

当前包括利福霉素在内的治疗肺结核的药品也对RNA多聚发生作用，但其药理不同。

Current TB drugs known as rifamycins also act on RNA polymerase , but they do it in a different way .

电解法处理利福霉素SV钠废渣分离液的研究

Study on treating the separated fluid of rifamycin SV sodium scrap by electrolytic method

甘油对利福霉素SV生物合成的影响

Effect of Glycerol Addition on Rifamycin SV Biosynthesis

应用均匀设计的方法对利福霉素SV发酵培养基中的氮源配比进行优化。

Uniform design method was employed to optimize the medium for production of rifamycin SV .

利福霉素生产菌产生钝化RifSV物质的分离及性质研究

Isolation and properties or Rifamycin SV-inactivation substance produced by Rif SV-pro-ductive strain

盐析法从利福霉素SV钠废渣中回收蛋白质的研究

Study of retrieving protein from the waste dregs of rifamycin SV sodium by salting out method

CNS对多种抗菌药物耐药，对万古霉素敏感，对利福霉素、复方新诺明、环丙沙星（除溶血葡萄球菌外）耐药率相对较低。

The drug-resistant rate of CNS ( except S.haemolyticus ) to rifampicin , trimethoprim / sulfamethoxazole and ciprofloxacin was relatively lower .

利福霉素SV钠盐药渣制取粗蛋白的工艺研究

The Technological Research on Preparation of Raw Protein Feed from the Medicinal Residue of Rifamycin SV Sodium Salt

方法采用摇瓶发酵，优化巴比妥钠初始含量及中间补加策略，通过测定发酵液中利福霉素B的效价及菌体浓度来确定合适的发酵工艺。

Methods In shaken flask culture , the content and feeding strategy of barbital sodium during the fermentation of rifamycin B was optimized and the suitable fermentation technology was also defined by determining the potency of rifamycin B and PMV of mycelia in fermentation broth .

利福霉素B发酵放大Ⅱ.从15L发酵罐到7m~3发酵罐和60m~3发酵罐流加补料发酵放大

Scale-up of rifamycin B fermentation ⅱ . Scale-up of rifamycin B fed-batch fermentation with continuous feed from 15L fermenter to 7m ~ 3 fermenter and further to 60m ~ 3 fermenter

利福霉素衍生物Rifabutin的临床药理研究进展

Progress of clinical pharmacological study on rifabutin

有机酸分析结果显示，甘油的加入导致乙酸和琥珀酸在胞外积累的增加，促进了EMP和TCA代谢途径，有利于利福霉素SV合成前体的积累。

The results of organic acids analysis demonstrated that adding glycerol led to the accumulation of acetic acid and succinate , thus malonyl-CoA and methylmalonyl-CoA biosynthesis was strengthened ; consequently the production of rifamycin SV production was improved .

方法利福霉素菌种03-C3经过紫外线照射150S后涂布于0.2%酪氨酸平面上得到中间突变菌株在含利福霉素4000u/ml平面上进行耐药处理。

Methods : Rifamycin mold mushroom spawn 03 & C3 after the ultraviolet ray to 150S and then spreads in 0.2 % tyrosine plane and obtains the variety strain .

利福霉素类及化学类抗结核药物的快速薄层鉴别方法

Rapid Identification Method on Rifomycins and Chemical Anti-tuberculosis Drugs by TLC

利福霉素治疗急性严重感染的临床评价

Clinical therapeutic evaluation of rifamycin injection in treating acute serious infections

利福霉素产生菌发酵培养基的研究

Studies on the fermentation medium of Nocardia mediterranei producing rifamycin SV

利福霉素钠注射液降压物质检查法研究

Study on the Depressor Substance Test of Rifamycin Sodium Injection

利福霉素治疗社区获得性肺部感染52例

Rifamycin in treating community-acquired pulmonary infections in fifty-two patients

利福霉素高产菌株快速筛选方法的建立及应用

Establishment and Its Application of a Fast Screening Method for Rifamycin SV-Producing Strain

利福霉素产生菌1074-105~菌株的选育

Selective breeding of Rifamycin Producing Strain Nocardia Mediterranea 1074-105

利福霉素S的反应性和构效关系

A study on the reactivity of rifamycin s and its structure - activity relationship

利福霉素中氯仿不溶物的研究

A study on chloroform insoluble substances in Rifamycin

大孔吸附树脂法分离利福霉素S钠盐的初步探讨

A preliminary study on separation of sodium salt of rifamycin s with macroporous adsorbent resin