功能缺陷

这提示PEC中起阻抑耐受诱导作用的主要细胞是Mφ，新生小鼠Mφ辅助功能缺陷可能是NITT模型建立的重要原因。

This suggested that M φ was responsible for interruption of tolerance and the functional deficiency of M φ in newborn mice might be the main cause of induction of neonatal tolerance .

我们的研究结果描述哮喘中CD4+CD25+Tregs一种新的功能缺陷，这种缺陷可能是过敏性哮喘的一种新的发病机制。

Our findings identified a new functional deficiency of CD4 + CD25 + T cells in asthma patients . This deficiency may be involved in the pathogenesis of allergic asthma .

血友病B是一种严重的凝血功能缺陷遗传病，由于现行的治疗方法对血友病B的治疗效果均不令人满意。

Haemophilia b is a kind of serious cruor-defective inhering diseaes .

2型糖尿病患者一级亲属胰岛素抵抗与胰岛B细胞功能缺陷的临床研究

Study of insulin resistance and impaired insulin secretion in first-degree relatives of type 2 diabetic patients

Rice说，这项发现与之前许多研究结果相一致，表明语言功能缺陷常常与阅读能力障碍并存。

Rice said the findings are consistent with numerous reports documenting that language impairments and reading disability often co-exist .

结论：MM患者可能存在单核-巨噬系统和红细胞免疫功能缺陷。

Conclusion : MM patients might have impaired monocyte-phagocyte system and red cell immune function .

结果：治疗组经心理治疗后社会功能缺陷均分明显降低（P均<0.01）。

Results : The average scores of social dysfunction had significantly decreased by psychotherapy in the trail group ( P < 0.01 ) .

主要表现为胰岛β细胞破坏，致其功能缺陷，数量减少乃至缺失。保持和补足B细胞数量，是预防和治疗糖尿病的一条重要途径。

A significant method to prevent and treat DM is to maintain and make up the loss of the islet cell mass .

结果①秩和检验显示C组与I组和R组之间神经功能缺陷评分差异明显（P均＜0.05）。

Results ( 1 ) The scores of neurological deficits in group C were different from those in group I or group R.

现就DNA损伤检控系统在维持端粒稳定中的作用及其对功能缺陷端粒的应答作一简要综述。

Here , we review recent studies defining the roles of DNA damage checkpoint in telomere maintenance and in response to telomere dysfunction .

上皮性卵巢癌IL-10表达与其腹腔免疫功能缺陷的研究

Relationship between IL-10 Expression and Peritoneal Immunodeficiency in Ovarian Epithelial Carcinoma

结论：LD儿童存在额叶执行功能障碍，有认知功能缺陷。

Conclusion : LD children suffered the frontal executive function deficits and cognitive dysfunction .

经历3h缺血和24h再灌注后，按0～5分级标准判断神经功能缺陷程度。

Neurologic outcome was scored with a 0-5 grading scale .

匹多莫德对免疫功能缺陷小鼠脾组织TNF-α和IL-6表达及相关免疫药理作用的研究

Effects and mechanisms of pidotimod on expression of TNF - α and IL-6 in immune-depressed mice spleen

结论1.矮小儿童所占比例最大的为特发性矮小，其次为下丘脑-垂体及其IGF轴功能缺陷。

The second are functional defects of hypothalamic-pituitary IGF-1 axis .

背景与目的：胃癌是消化道常见的恶性肿瘤，其发生可能与DNA修复功能缺陷有关。

Background and Objective : Gastric carcinoma is the most common malignant tumor , whose development maybe associated with the absence of DNA repair function of cells .

CD44功能缺陷似乎是皮肤萎缩发病的基础。

Defective CD44 functioning appears to underlie the pathogenesis of atrophy .

任何一种DNA修复基因及其产物表达异常，都会引起细胞修复功能缺陷，使基因租不稳定，细胞内错误信息累积，以致细胞恶性转化。

Any abnormal expressions of DNA repair gene and their products may lead to the absence of DNA repair functions , accumulating of incorrect information and malignancy of cells .

方法以高转移性人肺癌PG细胞为材料，该细胞的间隙连接基因Cx43表达抑制，细胞通讯功能缺陷。

Methods A highly metastatic human lung carcinoma cell line PG was used .

创伤后应激综合征（PTSD）患者通常都有认知功能缺陷。

Post traumatic stress disorder ( PTSD ) patients often have cognitive deficits .

目的探讨胰岛素抵抗与胰岛B细胞功能缺陷在2型糖尿病（T2DM）发生中的作用。

Objective To investigate the role of insulin resistance and impaired insulin secretion on development of type 2 diabetes mellitus ( T2DM ) .

随着经济全球化的加快和我国加入WTO的日益临近，“小额多数”的现代型纠纷不断涌现，但我国的代表人诉讼制度存在严重的功能缺陷。

With the development of globalization and the approaching of China 's entrance to WTO , disputes concerning " small amount of claim but lange amount of victims " arise frequently .

各组动物于再灌注后24小时行神经功能缺陷评分，随后灌注固定取脑组织，免疫组织化学染色检测海马CA1区Bax和Bcl-2的表达。

The neurological deficit scores of all rabbits were evaluated at 24h after reperfusion , the expression of Bax and Bcl-2 were detected with immunohistochemistry staining .

结论ADHD儿童智力、记忆力、注意力水平低于正常儿童，且具有选择性抑制、语音信息的工作记忆和计划的执行功能缺陷。

ADHD children have deficiency in executive functions , such as selective inhibition , working memory and plan implementation .

方法：使用社会功能缺陷筛选表（socialdeficitscreeningscale，SDSS）和焦虑症状自评量表（self-ratinganxietyscale，SAS）对109例绝经期妇女进行了评估。

METHODS : Totally 109 menopausal women were evaluated by social deficit screening scale ( SDSS ) and self rating anxiety scale ( SAS ) .

T和NK细胞联合免疫功能缺陷型&PBI/2beige裸鼠的培育及其在癌生物学研究中的初步应用

A Breeding of T and NK Cell Combined Immunodeficient PBI / 2 Beige Nude Mouse and Its Primary Application in the Biological Research on Cancer

产生MSI的主要原因是MMR功能缺陷，不能正常发挥错配修复作用，引起复制差错，导致基因组不稳定，进而引起癌变。

MSI caused by the defective functions of MMR plays an important role in the carcinogenesis .

ROS介导的精子质膜过氧化损伤，可以解释在高比例的不育病人中观察到的精子功能缺陷。

ROS mediated peroxidative damage to the sperm plasma membrane may account for defective sperm function observed in a high proportion of infertility patients .

目的：重度抑郁症（majordepressivedisorder，MDD）患者不仅优先加工负性刺激，而且缺乏对正性刺激加工的偏向，本研究探讨重度抑郁症患者情绪刺激抑制功能缺陷的神经关联。

Objective : Individuals with major depressive disorder ( MDD ) not only preferentially process negative stimuli , but also lack a bias for the preferential processing of positive stimuli .

前言：目的：通过整合视听连续执行测试（IVACPT）对认知功能缺陷儿童的测试分析，以探讨其辅助诊断价值。

Objective : To assess the assist diagnosis value of applying IVA CPT on children with cognitive deficiency .