蛋白尿

狼疮性肾炎患者血清DNA－抗－DNA免疫复合物与蛋白尿和肾脏病理类型的关系

Relationship of DN A-anti-DNA immune complexes to proteinuria and renal histopathologic

目的：探讨孤立性蛋白尿（IP）患儿的病理组织学特征、治疗及预后。

Objective To discuss the pathologic features , treatment and prognosis of the children with isolated proteinuria ( IP ) .

结果表明，血压越高，蛋白尿和水肿程度越严重，眼底改变的发生率及程度也随之提高，（P值分别为<0.001，<0.001和0.05），眼底改变和年龄无关。

The result showed that the higher the blood pressure was the higher the occurence of the severity fundus oculi changes .

能以自／旁分泌方式使正常的T、B淋巴细胞，B淋巴细胞白血病细胞免于凋亡，G-CSF与肾炎（包括LN）、蛋白尿间可能存在相关关系。

G - CSF is related to nephritis ( including LN ) proteinuria .

结果：①T组血清肌酐（SCr）水平显著高于NonT组，蛋白尿和血尿也较NonT组严重；

Results : Group T had a significantly higher level of serum creatinine than Group non T.

蛋白尿与IgA肾病小管间质病理损害的关系研究

Relationship between Proteinuria and Tubulointerstitial lesions in Patients with IgA Nephropathy

结果D组出现明显蛋白尿，低蛋白血症及高胆固醇血症，与C组比较差异有显著性（P<005）。

Results Group D occurred massive proteinuria , hypoalbuminemia and hypercholesterolemia , which had significant differences compared with group C ( P < 0 05 ) .

AngⅡ受体拮抗剂对糖尿病肾病蛋白尿的治疗效果及分析

Effect of angiotensin ⅱ receptor antagonist on proteinuria in diabetic nephropathy

临床上DN一旦出现持续性蛋白尿，若缺乏合理有效的干预，其肾功能将不可遏制地进行性下降。

Once the persistent proteinuria appeared , the renal function would decrease progressively .

然而，在接受抗高血压药物治疗的患者中，蛋白尿和HF没有显著相关性。

However , there was no significant association between albuminuria and HF in patients taking antihypertensive treatment .

其中正常蛋白尿阶段的糖尿病患者与正常成人组之间肾脏实质分级无明显不同（p0.05）。

Renal parenchymal echo of diabetes patients with the normal proteinuria and normal adults were not significantly different ( p0.05 ) .

IgA肾病的主要临床特点为血尿，也可以伴蛋白尿。

The basic clinic manifestation of IgAN is hematuria ( with or without proteinuria ) .

提示保肾康对IgA肾病血尿、蛋白尿具有一定疗效。

It is revealed that " Baoshen Kang " has positive effects on IgA nephropathy .

枸杞对运动大鼠肾脏Bcl-2、Bax表达和运动性蛋白尿的影响

Effect of Lycium Barbarum on the Motility of Rats ′ Kidney Bcl-2 and Bax Expression and Athletic Albuminuria

三靶点治疗IgA肾病中量蛋白尿的临床研究

Clinical Research on Therapy of Three Targets in the Treatment of IgA Nephropathy with Moderate Proteinuria

表现为肾病范围蛋白尿的IgA肾病临床、病理及预后研究

The Analysis of Clinical , Pathological and Prognostic Relationship of IgA Nephropathy Presented by Nephrotic Proteinuria

结论：大量蛋白尿和高血压可能促进IgA肾病的肾功能损害进展。

Conclusion : Severe proteinuria and hypertension may aggravate the damage in renal function in IgA nephropathy .

结果GH组的肾小球增生、硬化程度，24小时蛋白尿，高脂血症，低蛋白血症均明显重于模型组（p＜0.01）。

Results Glomerular mesangial proliferation glomerular sclerosis urinary protein hyperlipidemia hypoalbuminemia of GH-treated AN rats were significantly severer than AN rats ( p < 0.01 ) .

临床蛋白尿DN患者约5&10年后将不可逆地进展至终末期肾病（end-stagerenaldisease，ESRD），而最终需行肾脏替代治疗。

The DN patients with clinical proteinuria will irreversibly lead to end-stage renal disease ( ESRD ), and need renal substitution treatment .

贝那普利可减轻蛋白尿，降低血清CysC、血浆MMP-9浓度而有肾保护作用。

Lotensin could contribute to relieve proteinuria , cut down the concentration of serum Cys C , plasma MMP-9 to protect kidney .

目的探讨NPHS1基因突变中Finmajor和Finminor突变与狼疮肾炎（LN）蛋白尿发生的关系。

Objective To explore the correlation between Fin major or Fin minor mutation and proteinuria in lupus nephritis ( LN ) .

DM临床蛋白尿组（DM3组）20例，UAER>200μg/min。

Group DM3 : UAER > 200 μ g / min , 20 cases .

IgA肾病的临床病理类型多种多样，但仍以血尿和血尿伴蛋白尿最常见。

There are many pathological styles of IgAN , but the most commonly clinical symptoms are hematuresis and hematuresis accompanied with proteinuria .

MN以脾肾阳（气）虚型最为多见，与MN水肿、蛋白尿的临床表现一致，对MN的中西医结合治疗具有指导意义。

The deficiency of spleen and kidney yang ( gas ) was the main Syndrome types , as consistent with the edema , proteinuria of clinical manifestations .

幼年大鼠蛋白尿形成早期肾小管间质CTGFmRNA表达趋势及意义

Trend of Expression and Implication of Connective Tissue Growth Factor ( CTGF ) mRNA in Early Tubulointerstitial Lesions of Young Rats with Protein Overload

IgA肾病主要表现为蛋白尿并血尿；膜性肾病、高血压肾痛主要表现为单纯性蛋白尿。

Major clinical manifestations were proteinuria and hematuria in IgA nephropathy , while single proteinuria was major in membranous nephropathy and hypertensive nephropathy .

Kappa统计利用临床相关的蛋白尿的分类评估两种方法的一致性。

Kappa statistic was employed to evaluate concordance between the two methods taking into account clinically relevant categories of proteinuria .

抗VEGF和TGF－β1的研究和应用可能是治疗NS蛋白尿及改善本病预后，防止肾纤维化的重要手段。

Anti-VEGF and Anti - TGF - β 1 may be a important means in treating proteinuria , improving the prognosis and preventing the fibrosis in PNS .

目的观察加倍剂量氯沙坦（losartan）对老年2型糖尿病肾病患者蛋白尿的影响。

Objective To observe the effect of double dosage losartan in the treatment of type-2 diabetic renal proteinuria in elderly people .

目的调查血管紧张素Ⅱ（AngⅡ）受体拮抗剂对糖尿病肾病蛋白尿是否有明确的疗效和对肾功能的保护作用。

Objective To investigate the effects of Angiotensin ⅱ receptor antagonist on proteinuria in patients of diabetic nephropathy and its protection of renal function .