蛋白质数据库

本文描述了如何使用DB2中的pureXML和关系型数据管理特性来有效存储和查询蛋白质数据库（ProteinDataBank，PDB）。

This article has described how to use pureXML and relational data management features in DB2 to efficiently store and query the Protein Data Bank ( PDB ) .

目前蛋白质数据库（ProteinDataBank，PDB）中有26个关于HIV-1整合酶的晶体结构，但仅仅是包含整合酶的单个结构域或其中的两个结构域，无整合酶全酶的晶体结构。

At present , there are 26 crystal structures of HIV-1 integrase in the protein data bank , which include single domain or two domains of it , but none of them is the holoenzyme structure of HIV-1 integrase .

IBMPc微机上的蛋白质数据库及其管理系统

A Protein Database and the Management System on IBM PC Computers

运用隐马尔可夫模型，利用Perl编程，以几种模式生物的蛋白质数据库为基础，构建了目标基因的全基因组预测的新方法。

Based on the protein databases of several model species , this study developed a new method of the Genome-wide prediction for the target genes , using Hidden Markov model by Perl programming .

近年来，由于基因银行（GeneBank）和布鲁海文蛋白质数据库（PDB）发展得很快，为了分析这些海量数据，生物信息学应用而生，并得到了迅速发展。

In recent years , because GeneBank and PDB have grown very rapidly , bioinformatics has been born to analyze these enormous data and developed very rapidly .

BlastP是用于在蛋白质数据库中搜索类似序列的。

BlastP is used for searching protein databases for similar sequences .

根据检测的肽质量指纹图谱（PMF）在蛋白质数据库中比对，没有检索到与之相匹配的任何蛋白，可能为一种未报道的新蛋白。

According to comparison peptide mass fingerprinting ( PMF ) in the protein database , there is no search to match any protein , may be a new unreported protein . 3 .

蛋白质数据库（PDB）由几个成员组织管理，这些成员组织分别负责生物数据的存储、维护、处理以及将其免费提供给科研领域。

The Protein Data Bank ( PDB ) is managed by several member organizations responsible for depositing , maintaining , processing , and freely providing this biological data to the scientific community .

我们使用BGIGENEFINDER（BGF）对6×家蚕全基因组序列进行分析后，得到了蛋白质数据库B，该数据库的总记录数为14632。

By using the BGI GENE FINDER ( BGF ) server to scan from the existing silkworm genome sequences , the coverage of which was 6 ×, we got a protein database B , in which the total number of records is 14,632 .

此外，盐芥和拟南芥在cDNA和氨基酸水平上分别有90%和95%的同源性，可以方便的将拟南芥的很多信息（基因、蛋白质数据库以及突变体系等）移至盐芥耐盐性的分子生物学研究。

Besides , salt cress and Arabidopsis share 90 % and 95 % identities on cDNA and amino acid sequences respectively , so it is convenient to transfer informations of Arabidopsis ( gene database , protein database and mutant lines ) to molecular analysis on salt tolerance of salt cress .

虽然国际上有些蛋白质数据库已经收录了部分铜离子螯合蛋白质，但是收录信息不全面，更新速度较慢，蛋白质的结构信息涵盖较少是其主要缺点，DCCP则可以弥补其不足。

Although there are some databases where some samples of copper-chelating proteins have been involved , the information is not enough and the rate of update is very slowly .

检索蛋白质数据库证明其中的蛋白质点包括橡胶延长因子（REF）和橡胶过敏蛋白Hev3等典型的橡胶粒子膜蛋白，另外还有一些功能未知的蛋白质。

Some protein spots were taken randomly and analyzed by MALDI-TOF . Through searching the protein database and blast , some previously known proteins were further identified including the rubber elongation factor ( REF ), rubber allergic protein Hev 3 , etc , and some were unknown proteins .

五龄家蚕若干组织器官蛋白质数据库构建

Protein Databank for Several Tissues Derived from Five Instar of Silkworm

蛋白质数据库中匹配间隙序列标签的自动机算法

An automata approach to match gapped sequence tags against protein database

一种基于信息论的蛋白质数据库搜索鉴定算法

A Database Search Algorithm Based on Information Theory for Protein Identification

经蛋白质数据库检索，尚无与之同源的序列。

Homologous sequence has not been found yet through blast in protein date base .

蛋白质数据库与结构基因组

Protein data banks and structural genomics

该框架以新的结果可视化和面向蛋白质数据库搜索的结构域和功能预测的整合为特色。

The framework features novel result visualizations and integration of domain and functional predictions for protein database searches .

其中，马的基因数据库中的记录量超过了2万，马的蛋白质数据库的记录超过3万。

The records of Horse Gene Database have over 20,000 and the records of Horse Protein Database have over 30,000.2 .

选择表达差异2倍以上的40个点，经质谱分析和蛋白质数据库检索成功鉴定出35个蛋白，其中17个在癌组织中上调，18个下调。

35 differential proteins , including 17 up-regulated proteins and 18 down-regulated proteins were successfully identified by MS analysis and database searching .

由于膜蛋白的疏水等特性，其结构数据在整个蛋白质数据库中所占比例非常小，实验方法获取膜蛋白相互作用更是困难，所以已知的膜蛋白相互作用数据非常少。

Experimental methods for membrane protein interactions are more difficult , so the known data about membrane protein interactions is very little .

蛋白质数据库（PDB.org）是一个有关生物分子（尤其是蛋白质）结构数据的全球档案库。

The Protein Data Bank ( PDB . org ) is a worldwide archive of structural data about biological molecules , mostly proteins .

介绍了蛋白质数据库中数据的存储和处理、交换、质量、分配和询问。

The data deposition , processing , exchange , quality , distribution and query in protein data banks were introduced in this paper .

高血压相关基因和蛋白质数据库的初构初中生英语语音意识测验的编制与分析

The preliminary construction of the database of hypertension related genes and proteins The Preliminary Construction and Analysis of Middle School 's Phonological Awareness Test

7初步建立了肺癌组织细胞分泌蛋白质数据库，包含肿瘤细胞表达蛋白质177个，正常上皮细胞表达蛋白质150个（新发现的分泌蛋白质在肿瘤中为161，在正常中为137）。

Vii . Databases of secretory proteins were constructed , including 177 proteins expressed by cells from tumoral tissues and 150 from normal tissues .

序列数据库中以基因数据库和蛋白质数据库为主，非序列数据库以文献数据库和图片数据库为主。

The sequence libraries mainly include Gene Database and Protein Data Bank . The non - sequence library mainly include Bibliographic Database and Picture Database .

目的：构建高血压相关基因和蛋白质数据库，以促进高血压医学生物信息学的研究。

Objective : To constract hypertension Related Gene and Protein Database and provide a useful query tool for the research of hypertension in biomedical information .

获得的170条表达序列标签可分成106组，其中的43组，占466%，在蛋白质数据库中存在同源蛋白。

The 170 ESTs were grouped into 106 non redundant clusters , among them , 43 have homologous proteins in public data banks , counting for 46 6 % .

选用蛋白质数据库中的天然蛋白质作为测试靶蛋白，结果表明，采用该模型和方法取得了较好的结果，预测结构相对于天然结构的均方根偏差在0.30～0.70nm之间。

Testing on several real proteins from Protein Data Bank ( PDB ) shows the good results obtained with the model and method . The root mean square deviations ( RMSD ) of the predicted structures relative to the native structures range from 0.30 to 0.70 nm .

研究证明利用蛋白质数据库的结果，可以得到基因表达及其产物修饰的信息。

The N terminal sequences of 27 proteins were first found in silkworm , and all these data were registered in SWISS PROT through the Internet The results suggested that the information of gene expression and post translational modification could be obtained by the information of protein databank .