组织工程骨

VEGF基因修饰组织工程骨促进兔大段骨缺损修复的实验研究

Utilization of VEGF Gene Modified Tissue Engineering Bone in Promoting the Healing of Rabbit Bone Defect

结论EPCs可以促进组织工程骨修复大段骨缺损时的成骨能力，加速骨愈合。

Conclusion EPCs can improve bone forming ability of tissue engineering bone in repairing segmental bone defect .

C组：组织工程骨未行低温保存；

Group C : Tissue engineered bone without cryopreservation .

B组：组织工程骨用不添加冻存保护剂的保存液保存；

Group B : Tissue engineered bone had been stored in preservation solution without cryopreservation medium .

1，25-（OH）2D3作为生物活性因子在组织工程骨中的应用

The Role of 1 , 25-dihydroxyvitamin D_3 as a Cellular Growth Factor in Bone Tissue Engineering

A组植入自体髂骨，B组植入组织工程骨，术后骨科常规处理。

Autogeneic iliac bone was implanted in group A , while tissue engineered bone was implanted in group B. Routine postoperative treatment in orthopedic surgery was taken .

bFGF基因修饰组织工程骨移植修复颌骨缺损及相关机制的实验研究

Research on Repairing Mandibular Defect with Tissue Engineering Bone Graft Modified by bFGF Gene

转染VEGF的BMSC复合冻干骨组织工程骨研究

Study on the Tissue Engineered Bone Composed of Freezing and Drying Bone and BMSC Transfected VEGF

兔BMSCs和纳米仿生支架构建功能性管状组织工程骨

Combination of Rabbit BMSCs Cell Sheet and Nano Biomimetic Scaffold for Functional Tubular Bone Tissue Engineering

目的：为了合理使用藻酸钙凝胶于可注射组织工程骨中，对藻酸盐溶胶的pH值和藻酸钙凝胶的机械强度进行测定。

AIM : To measure the pH of alginate solution and mechanical properties of alginate gels so as to apply calcium alginate gels in injectable tissue engineered bone reasonably .

结果表明制备的可注射组织工程骨材料具有良好的生物相容性，MSCs能够在材料中正常增殖。

The results showed MSCs could grow well in the hydrogel , indicating that the prepared tissue engineered bone had a good biocompatibility .

Bio-Oss胶原结合骨髓基质细胞构建组织工程骨的实验研究

Experimental construction of tissue engineering bone with Bio - Oss collagen and BMSCs

结论MSCs复合n-HA/PLA构建的组织工程骨可作为自体骨的替代材料修复节段性骨缺损。

Conclusion The fabrication of tissue engineering bone with MSCs and n-HA / PLA could repair the segmental bone defect as the substitute of autograft .

BMP-2基因治疗的组织工程骨联合显微外科血供重建修复兔桡骨缺损的实验研究

BMP-2 Gene Enhanced Tissue Engineering Bone and United with Microsurgery Techniques for Repairing Segmental Radial Bone Defects in Rabbits

目的探讨组织工程骨修复骨缺损，内源性骨形态发生蛋白（BMP）在组织工程骨再生过程中的分布及作用。

Objective To explore the distribution and effect of endogenic bone morphogenetic protein ( BMP ) in repairing rabbit skull with tissue engineered bone .

目的：探讨利用旋转式细胞培养系统（RCCS）在体外快速构建组织工程骨的可行性。

Objective : To explore the possibility of rapid construction of tissue engineered bone in vitro by RCCS .

组织工程骨与Bio-Oss修复大鼠下颌骨缺损的比较研究

Tissue Engineering Bone and Bio-Oss in the Restoration of a Mandibular Critical Size Defects in Rats

沥滤方法制备了β-TCP／PLLA多孔支架材料，将支架材料与大鼠骨膜成骨细胞复合获得新型组织工程骨修复材料。

A novel tissue engineering composite was developed by combining β - TCP / PLLA composite with rat periosteum derived osteoblasts .

BMP-2基因转染的人骨髓基质干细胞复合PLA/PCL支架体外构建组织工程骨

Construction of Tissue Engineering Bone with BMP-2 Gene Transfected Human Bone Marrow Stromal Cells and PLA / PCL Biodegradable Scaffold in Vitro

仿生BCP组织工程骨块重建股骨头骨缺损区的实验研究

Reconstruction of Bone Defect in the Femoral Head by Using Biomimetic BCP Tissue Engineering Bone : An Experimental Study

组织工程骨组和筋膜瓣组分别取9只山羊的BMSc体外进行诱导分化，之后与CHAP复合。

After finished culturing and inducing the BMSc , CHAP of group of tissue engineered bone and of fascia flap was combined with it .

~（99m）Tc-MDP动态骨显像在定量监测组织工程骨修复兔颅骨缺损中的应用

Using dynamic bone imaging with ~ ( 99m ) Tc-MDP for quantitatively evaluating the repairing of skull defect with tissue-engineered bone graft in rabbits

目的制备山羊脱钙骨基质（decalcifiedbonematrix，DBM），研究其物理和生物力学特性，为其作为理想的组织工程骨支架材料提供理论依据。

Objective To prepare completely decalcified bone matrix ( DBM ) and study its physical characteristics and biomechanical properties in order to afford theoretical base for DBM as ideal scaffold of bone tissue engineering .

目的：了解骨髓基质干细胞（MSCs）复合纳米羟基磷灰石/聚乳酸（n-HA/PLA）构建组织工程骨的异位成骨作用。

Objective To study the effect of ectopic osteogenesis of fabrication of tissue engineering bone with bone marrow stromal cells ( MSCs ) and nano-hydroapatite / polylactic acid ( n-HA / PLA ) .

EPCs促血管化组织工程骨修复大段骨缺损的早期组织学评价

A histologic evaluation on vascularization of tissue engineering bone induced by endothelial progenitor cells ( EPCs ) for repairing large segmental defects in early period of bone healing

目的观察血管内皮祖细胞（EPCs）对组织工程骨修复兔桡骨大段骨缺损时成骨能力的影响。

Objective To investigate the effects of endothelial progenitor cells ( EPCs ) on the bone forming ability of tissue engineering bone during rabbit radius segmental defect healing .

目的评价骨形态发生蛋白2（BMP-2）基因修饰的组织工程骨联合血管束植入修复节段性骨缺损效果。

Objective To evaluate the effects of bone morphogenetic protein 2 ( BMP-2 ) gene modified tissue engineering bone combined with vascular bundle implantation in repairing segmental bone defect .

RGD多肽表面修饰对以HA-TCP为支架材料组织工程骨的修复作用有明显优化作用。

The surface modification of RGD peptide could optimize the repairing effect of tissue engineered bone produced by HA-TCP as scaffold material .

目的：探讨应用经血管内皮细胞生长因子（VEGF）转染的骨髓基质干细胞（BMSC）复合胶原蛋白海绵构建的血管化组织工程骨修复牙槽嵴裂的可行性。

Objective : To investigate the feasibility of the restoration of cleft alveolar with vascularised engineered bone constructed by collagen combined with vascular endothelial growth factor ( VEGF ) gene transfected bone mesenchymal stem cells ( BMSC ) .

本试验探讨骨髓间充质干细胞（BMSCs）的生物学特性和成骨分化能力，研究以BMSCs为种子细胞、10%珊瑚羟基磷灰石（CHA）为细胞外基质材料构建的组织工程骨的成骨能力。

We studied the biological features of bone mesenchymal stem cells ( BMSCs ) of rabbits , and observed the effect of repairing rabbit skull defects by 10 % coral hydroxyapatite ( CHA ) embedded with BMSCs .