浓度依赖性

Zn~（2+）对PTP开放和细胞色素c释放的浓度依赖性双向调节

Bidirectional Regulation of Concentration-dependent Effect of Zn ~ ( 2 + ) on PTP Opening and Cytochrome c Release

上述效应在ASODN各组存在一定的时间浓度依赖性；

In each ASODN group , the effect above-mentioned has time - and concentration-dependent manner .

酶动力学实验显示蛋白酶K增加CYP27A1酶活性呈时间，蛋白酶K剂量及底物浓度依赖性。

Kinetic studies showed that the increased activity was time , proteinase K and substrate concentration dependent .

结论：DSS模型结肠炎症程度的轻重呈浓度依赖性。

Conclusions : DSS-induced acute mucosal injury was dependent on DSS concentration .

结论1,25（OH）2D3可以抑制体外培养的小鼠成骨细胞的增殖，并呈现一定的浓度依赖性。

Conclusions Cell proliferation of mouse osteoblasts can be inhibited by 1,25 ( OH ) _2D_3 in a concentration-dependent manner .

结果：1.辛伐他汀能诱导K562细胞凋亡，其作用具有浓度依赖性。

Simvastatin could induce apoptosis of K562 cells in concentration dependent manner . 2 .

G2可浓度依赖性地抑制乙酰胆碱（Ach）所致的第二时相收缩。

G_2 also inhibited the second phase contraction induced by Ach .

NE诱发的膜电位去极化有浓度依赖性且可被酚妥拉明阻断。

NE could induce membrane depolarization in a concentration dependent manner and could be blocked by phentolamine .

实验结果表明，BUT能够引起红细胞膜发生明显的脂质过氧化，表现为浓度依赖性地增加脂质过氧化终产物丙二醛（MDA）的含量。

BUT induced erythrocyte membrane lipid peroxidation significantly , shown by a startling increase in the level of malondialdehyde ( MDA ) .

Insulin（0.1-30nM）浓度依赖性地增加BK电流。

Application of insulin ( 0.1 ~ 30 nM ) increased the BK currents in a concentration-dependent manner .

ConA可浓度依赖性地促进T淋巴细胞增殖；

ConA stimulated T lymphocyte proliferation in an dose dependent manner ;

而且，抗ICAM-1单克隆抗体抑制PBMC黏附到眼眶成纤维细胞呈浓度依赖性。

Moreover , ICAM-1 monoclonal antibody inhibits the adhesion of PBMC and fibroblasts in concentration-dependent manner .

结果：TSA可诱导细胞凋亡，主要使细胞积聚在G2/M期，且呈浓度依赖性。

Results : TSA induced apoptosis of A549 cells and arrested cells in G_2 / M phase in a dose-dependent manner .

重组人IL-2可呈浓度依赖性抑制AGS细胞增殖。

RhIL-2 could inhibit the AGS cell proliferation in a concentration depended manner . 3 .

结论：AGEs呈浓度依赖性地诱导内皮细胞NF-κB的活化、Fn的基因表达上调，这可能与糖尿病慢性血管并发症的发生发展有关。

Conclusion The activity of NF - κ B and up-regulated expression of Fn mRNA induced by AGEs may contribute to chronic complications of diabetes .

藤黄酸体外对PHA诱导的正常淋巴细胞和LPS诱导的正常淋巴细胞的增殖有抑制作用且呈浓度依赖性。

GA could inhibit the proliferation of normal lymphocytes treated with PHA or LPS in concentration dependent manner .

薯蓣皂苷能够使Ox-LDL诱导的血管内皮细胞凋亡率降低，且呈一定的浓度依赖性。

Dioscin against BAECs apoptosis in Ox-LDL model , and present concentration dependent . 3 .

通过使用全细胞膜片钳技术证明了在心室肌细胞上银杏苦内酯B可浓度依赖性的缩短动作电位时程，主要与增大延迟整流型钾电流有关。

Ginkgolide B may shorten the action potential duration in a concentration-dependent manner which mainly due to the increase of the delayed rectifier potassium current ( Ik ) in single ventricular myocytes by using patch-clamp techniques .

结论：TAE具有机能和浓度依赖性的双向免疫调节作用。

Conclusion : TAE have a dual immunomodulatory activity in a function and concentration dependent manner .

结果：PDGFB链基因TFO对C6胶质瘤细胞PDGFB链基因的表达和细胞生长有明显抑制作用，而且抑制作用存在浓度依赖性。

Results : triplex-forming oligonucleotide can obviously inhibit the PDGF-B chain expression and the proliferation of C_6 glioma cells in concentration-dependent fashion .

结论新型有机硒化合物Eb能够诱导细胞凋亡，并且有浓度依赖性。

Conclusions The novel organoselenium compounds ( Eb ) induced apoptosis , and the apoptotic rates depended on the doses .

GQDs的光致发光（PL）强度呈激发波长、PH及浓度依赖性。

The intensity of GQDs ' photoluminescence ( PL ) depended upon excitation wavelength , pH and concentrations . 2 .

氯吡格雷对GES-1细胞的损伤呈浓度依赖性（P0.05），无时间依赖性。

GES-1 cells injury was induced by clopidogrel in a concentration-dependent manner , but in no obvious time-dependent manner .

QUI逆浓度依赖性、逆频率依赖性地增大TDR。

QUI augmented TDR in reverse concentration and reverse rate dependent fashion .

结果：IL-1β可诱导克罗恩病肠浆膜纤维细胞ICAM-1表达水平显著升高，而雷公藤内酯醇能显著抑制IL-1β的作用，并呈浓度依赖性。

Results : IL-1 β significantly induced ICAM-1 expression in SFs . And triptolide inhibited the effects of IL-1 β in a dose-dependent manner .

BPA可引起人子宫内膜细胞甾体激素受体基因及蛋白水平的改变，且这种改变具有浓度依赖性。

BPA can change human endometrial cells steroid receptors gene and protein level , and this alter have concentration-dependent .

RTX的全部效应均是时间和浓度依赖性的。

These effects were shown to be time - and dose - dependent .

结果：EGCG显著抑制黑素合成和TYR活性，且呈浓度依赖性；

Results : The results showed that EGCG inhibited melanin synthesis and tyrosinase activity significantly compared with control .

GbE对FMLP激活白细胞呼吸暴发化学发光活性有明显浓度依赖性抑制作用。

There are concentration-dependant inhibition , in chemiluminescence produced by activated leukocyte with FMLP .

Leptin可刺激骨钙素分泌，呈浓度依赖性（P<0.05），但无时间依赖性（P>0.05）。

The leptin stimulated synthesis of osteocalcin of cells was found to be dose dependent ( P < 0.05 ), but not time dependent ( P > 0.05 ) .