治疗失败

很多病人没有按要求、按时、按次吃药，导致HIV病毒变异产生耐药性而使治疗失败。

Many patients are not required , on time and pay-per-view medicine , resulting in HIV virus resistance of treatment failure .

目的抗生素耐药越来越被公认为是根除幽门螺杆菌（hp）治疗失败的主要原因。

Objective Antibiotic resistance has increasingly been recognized as the major cause of treatment failure for Helicobacter pylori infection .

HIV感染者高效抗逆转录病毒治疗失败后的耐药研究

Drug resistance of HIV-infected patients after the failure of highly active antiretroviral treatment

结果三组治疗失败率无显著差异（P>005）。C组并发症发生率明显高于A、B两组（P<005）。

Results There was no significant difference ( P > 0.05 ) in the rate of therapeutic failure among three groups .

第一位患者治疗失败，很可能因为治疗时其B细胞已经太少。

The treatment failed in the first patient , probably because their beta cell count was too low when they started the treatment .

对化疗药物产生多药耐药（MDR）是AL患者治疗失败的主要原因。

Multidrug resistance ( MDR ) to chemotherapy is the main reason for treatment failure in patients with AL .

对产ESBLs肺炎克雷伯菌经验性抗生素治疗失败为CAP死亡的主要原因之一。

Most dead cases with CAP by ESBLs-producing Klebsiella pneumoniae were ascribed to empirical antibiotic therapy failure .

应用HBIG治疗失败时可以出现HBsAg与抗-HBs同时阳性。

HBsAg and anti-HBs simultaneously positive when the treatment was failed with HBIG .

初治时达CR是提高生存率的关键，复发和全身播散是治疗失败的主要原因。

The key of raising survival rate was the achivement of CR at the first treatment : Recurrence and diffusion were the main cause of failure .

目的研究分析部分GERD经临床常规抑酸治疗失败的原因，为临床处理难治性GERD提供理论依据。

Aim To study the causes of management failure of refractory GERD patients .

3HP感染及酸反流可能不是GERD治疗失败的直接原因。

HP infection and acid reflux may not be the direct causes of refractoriness .

由于HBV宫内感染或病毒变异可致免疫治疗失败，需进一步研究宫内感染的机制及病毒变异株。

Its necessary to explore the mechanism of intrauterine infection and identify the mutants of HBV , because intrauterine infection and mutation of HBV can cause failure to immunoprophylaxis .

对于股骨近端骨折治疗失败的患者，进行补救性的THR重建髋关节功能临床疗效满意。

THR is a satisfactory and safe way to salvage a failed treatment of proximal femoral fracture .

87例均伴有患侧轻~中度肾盂积水，其中46例合并结石远端输尿管狭窄，69例合并息肉或肉芽组织包裹，21例为ESWL治疗失败后。

Among them , 46 cases with ureteral stricture , 69 cases with polypus and 21 cases fail of ESWL .

MMP-9在人分泌期子宫内膜表达降低或缺陷可能是某些不明原因不孕症及反复IVF-ET治疗失败的原因之一；

The low expression of MMP-9 in secretive phase endometrium may be the cause of idiopathic infertility and repetitive failure of IVF-ET treatment .

核苷类逆转录酶抑制剂是一类重要的抗HIV-1药物，其耐药性病毒株的产生是导致抗HIV-1治疗失败的主要原因。

NRTIs are an important class of antiretroviral drugs , to which the emergence of resistant HIV-1 mutants is the major cause of failure of antiretroviral therapy .

第二，有一些临床研究暗示如果病人的万古霉素MIC值为2，那么他们的万古霉素治疗失败机率增加北京翻译公司。

Secondly , there have been a number of clinical studies that suggest that patients who have vancomycin MIC of2 have increased risk of vancomycin treatment failures .

背景：幽门螺杆菌（H.pylori）对抗生素的耐药率上升是导致根除治疗失败率上升的主要原因，对经标准方案根除H。

Background : The rising prevalence of antimicrobial resistance of Helicobacter pylori ( H. pylori ) is the major cause of increasing failure rate of anti-H.

NPPV治疗失败时及时改用有创通气可降低病死率，改善预后。

NPPV should be replaced promptly by tracheal intubation and invasive ventilation when failure occurs .

尽管三代头孢菌素不是AmpC酶的强诱导剂，但在临床应用时能选择出ampC基因去阻遏表达的突变株，对超广谱头孢菌素产生耐药性，从而使临床治疗失败。

Enzyme substrate is third generation cephalosporin which can choose clinical isolates with depressed expression of ampC gene , although it is not strong inducer .

方法总结24例梗阻性黄疸患者ERCP治疗失败后，实施PTBD与ERCP对接胆道支架植入术的治疗方法与临床效果。

Methods 24 patients with obstructive jaundice were treated by butt joint of PTBD and ERCP after the ERCP failure , and the clinical results were evaluated .

方法23例经CHOP方案治疗失败的NHL患者接受MINE方案化疗至少2个周期，MIT6~8mg/m2/d，静滴，d1；

Methods Total of 23 patients failing to respond to CHOP regimen were treated with MINE regimen and every patient had gotten at least 2 cycles treatment . MIT 6 ~ 8mg / m ~ 2 / d , IV on d1 ;

食管癌（EsophagealCarcinoma，EC）是消化道最常见的恶性肿瘤之一，而且具有较强的侵袭生长能力，肿瘤细胞的浸润转移是食管癌治疗失败和病人死亡的主要原因。

Background and purpose : Esophageal carcinoma is one of the most common malignant tumors in digestive tract , which has strong ability of invasion , and the infiltration 、 metastasis of tumor is the main reason of the death , also is the reason of the treatment failure .

目的比较股骨头缺血坏死显微外科保头治疗失败后全髋关节置换（THA）与初次全髋关节置换的疗效差别。

Objective To Compare the differences between the primary total hip arthroplasty ( THA ) and THA after failure of conservative treatment of osteonecrosis of femoral head . Methods One hundred and twenty-six hips were retrospectively studied .

结果总有效率（RR）为47.2%，完全缓解率（CR）为22.2%，一线治疗失败患者的RR为36.8%，复发者为58.8%。

Results Overall , 47.2 % of the patients responded , with 22.2 % having a complete response ( CR ) . Patients with front-line chemotherapy failure had a 36.8 % response rate ( RR ) and those with relapsed a 58.8 % RR .

结论VIP方案作为局限型SCLC患者的一线方案疗效优于标准EP方案，而且还可用于EP方案治疗失败病例的解救治疗。

Conclusion VIP regimen may be used as the first-line chemotherapy for localized SCLC , its efficacy is superior to that of EP regimen . VIP can also be used as salvage chemotherapy regimen for patients with SCLC who failed to EP regimen chemotherapy .

方法对6例药物保守治疗失败的病人采取宫腔镜下插管注药（MTX），观察hCG、附件区包块的变化、腹部体征、肝肾功能。

[ Methods ] 6 cases with chronic ectopic pregnancies with the failed treatment of systemic methotrexate were treated with injecting methotrexate through hysteroscopic tubal catheter under hysteroscope supervision , then quantitative hCG , adnexal mass , abdominal signs and liver and renal functions were examined .

治疗失败组在根除治疗开始后第4天HpSA试验的平均吸收值显著高于根治成功组。

The mean absorbance value of the HpSA test on the 4th day after the initiation of eradication therapy was significantly higher in the non-eradication group than in the group with successful eradication .

主要终点指标是客观肿瘤缓解率（ORR），次要终点指标是肿瘤缓解持续时间（DTR）、肿瘤进展时间（TTP）、肿瘤治疗失败时间（TTF）、安全性评估和毒副反应。

The primary endpoint was objective response rate ( ORR ), and the second endpoints were the durative time of remission ( DTR ), time of tumor progression ( TTP ), time of treatment failure ( TTF ), safety assessment and adverse events .

结论口腔与结肠黏膜尿道成形对长段尿道狭窄是较理想的术式；结肠黏膜较适合在常规手术治疗失败后或复杂性尿道狭窄10cm以上的治疗。

Conclusions Colonic mucosal and buccal mucosal grafts urethroplasty are feasible procedures for the treatment of long segment urethral stricture , and Colonic mucosal graft urethroplasty may be considered when more conventional procedures fail or complicated urethral strictures greater than 10 cm long .