抗核小体抗体

抗核小体抗体及抗C1q抗体在LN发病中起重要的作用。

Anti-nucleosome antibodies and anti-C1q antibodies are suggested to play a role in the pathogenesis of LN .

结论在LN患者中，存在着抗核小体抗体、抗C1q抗体的高表达。

Conclusion In patients with LN , anti-nucleosome antibodies and anti-C1q antibodies are significantly higher than control groups .

儿童系统性红斑狼疮抗核小体抗体和抗dsDNA抗体的检测和意义

Detection and Significance of Anti-nucleosome Antibodies and Anti-dsDNA Antibodies of Systematic Lupus Erythematosus in Children

SLE患者淋巴细胞凋亡活化程度与疾病活动程度和免疫效应功能紊乱密切相关，而淋巴细胞凋亡异常程度与抗核小体抗体水平的高低密切相关。

The degree of apoptosis activation of lymphocytes is correlated with disease activity and immune response dysfunction . The degree of lymphocytic apoptosis imbalance is associated with the level of anti-nucleosome antibodies .

抗核小体抗体水平、抗dsDNA抗体水平和抗组蛋白抗体水平均高于对照组。

The level of serum anti-nucleosomes antibody , anti-dsDNA antibody and anti-histone antibody were much higher than that of healthy controls .

红斑狼疮，系统性；临床特征；抗核小体抗体；

Lupus erythematosus , systemic ; Clinical features ; Anti-nucleosome antibodies ;

第二代抗核小体抗体检测对系统性红斑狼疮的诊断价值

Detection of second filial generation anti-nucleosome antibody in patients with systemic lupus erythematosus

抗核小体抗体；系统性红斑狼疮；

Anti-nucleosome antibody Systemic ; Lupus erythematosus ;

结果：抗核小体抗体在45例系统性红斑狼疮患者34例（75.5%）阳性，其敏感度和特异度分别为75.5%，93.1%；

Results The sensitivity of anti-nucleosome antibodies was 75.5 % with reasonable specifity ( 93.1 % ) in systemic lupus erythematosus .

目的探讨狼疮肾炎患者抗肾小球基底膜抗体（anti-GBM）与抗双链DNA抗体（anti-dsDNA）和抗核小体抗体（anti-NuA）的关系。

Objective To establish whether the anti-glomerular basement membrane antibodies ( anti-GBM ) correlate with anti-double stranded DNA antibody ( anti-dsDNA ) and anti-nucleosome antibodies ( anti-NuA ) in patients with lupus nephritis ( LN ) .