吡嗪酰胺

18例结核性脑膜炎血&脑脊液异烟肼、利福平、吡嗪酰胺浓度测定

Blood and CSF Isoniazid , Rifampin and PZA Level Determination in 18 Cases of Tuberculous Meningitis

方法：采用HPLC定量分析法分别测定给药后受试者血浆中利福平、异烟肼及吡嗪酰胺三种有效成分浓度。

METHOD : Rifampicin , Isoniazid and Pyrazinamide in plasma wad determined by HPLC .

利福平吡嗪酰胺联用方案与异烟肼标准方案预防性治疗潜在结核感染效果的Meta分析

Rifampicin Plus Pyrazinamide versus Isoniazid For Treating Latent Tuberculosis Infection : A Meta-analysis

目的比较利福平吡嗪酰胺联用方案（RZ）与异烟肼方案（H）化学预防潜在结核感染的有效性和安全性。

Objective To evaluate the efficacy and safety of rifampicin plus pyrazinamide versus isoniazid for prevention of tuberculosis among persons with or without HIV-infection respectively .

吡嗪酰胺（PZA）是结核病短程化疗中的一线抗结核药物，由吡嗪酰胺酶转换成为活性形式吡嗪酸而生效。

Pyrazinamide ( PZA ) is an important component in short-course tuberculosis chemotherapy .

这四种抗生素分别是异烟肼、利福平、吡嗪酰胺和乙胺丁醇。南非的科学与工业研究理事会（CSIR）的科学家已经把这些药物放入了肉眼不可见的纳米颗粒中。

South African scientists from the Council for Scientific and Industrial Research ( CSIR ) have incorporated these drugs into nanoparticles that are invisible to the human eye .

应用偏最小二乘法结合近红外光谱法（NIRSPLS）对吡嗪酰胺片中吡嗪酰胺的含量进行了非破坏性定量分析。

Near infrared diffuse reflectance spectroscopy with partial least square fitting ( NIRSPLS ) was applied for nondestructive quantification of the content of Pyrazinamide in Pyrazinamide tablets .

方法：采用明胶和聚己内酯复合包裹法将异烟肼、利福平、吡嗪酰胺和乙胺丁醇等4种抗结核药物按一定浓度和配比与重组合异种骨（RBX）复合，制备抗结核骨。

Method : Anti-TB bone was made of reconstituted bone xenograft ( RBX ) combined with 4 antituberculosis drugs ( Isoniazide , Rifampicin , Pyrazinamide , Ethambutol ) at certain concentration and encapsulated by gelatin and polycaprolactone .

吸收系数法测定吡嗪酰胺片中溶出度的研究

Determination of dissolution of pyrazinamide tablets by absorption coefficient method

结核分支杆菌吡嗪酰胺敏感试验方法的比较研究

Comparison of tests of susceptibility of Mycobacterium tuberculosis to pyrazinamide

卡利克斯公司是世界公认的吡嗪酰胺的最大供应商。

CALYX globally ranks as the largest supplier of Pyrazinamide .

其它两种药物是乙胺丁醇和吡嗪酰胺。

The other two medicines are Ethambutol and Pyrazinamide .

最常用的抗结核药品是异烟肼、利福平、吡嗪酰胺和乙胺丁醇。

The most common anti-TB medicines are isoniazid , rifampicin , pyrazinamide and ethambutol .

改变药典规定波长实现吡嗪酰胺片溶出度的在线过程分析

Processing analysis of dissolution rate of Pyrazinamide Tablets

对照组用链霉素，异烟肼对氨基水杨酸钠、利福喷汀、乙胺丁醇、吡嗪酰胺，疗程均为18个月。

The course of treatment was 18 months .

结核分枝杆菌耐吡嗪酰胺分子机制研究

Molecular basis of Mycobacterium tuberculosis to pyrazinamide resistance

异福酰胺片中的吡嗪酰胺比重较轻，且带有静电。

Pyrazinamide has light proportion and static .

对每例进行异烟肼、利福平、吡嗪酰胺、乙胺丁醇、链霉素的斑贴试验。

Each cases was conducted the patch test of Isoniazid , Rifampicin , Pyrazinamide , Ethambutol streptomycin .

目的观察复方甘草酸单胺联合利福平、吡嗪酰胺治疗布氏杆菌病（布病）的临床疗效。

Objective To observe the curative effect of potenlin , rifampicin and pyrazinamide combined therapy on brucellosis .

在拘留所完成的结核病预防治疗：目标疗法及利福平/吡嗪酰胺方案与异烟肼方案的比较

Completing tuberculosis prophylaxis in jail : targeting treatment and comparison of rifampin / pyrazinamide with isoniazid regimens

目的：观察护肝益肺颗粒对吡嗪酰胺致肝损害小鼠的保护作用。

OBJECTIVE To observe the protective effect of Hugan Yifei pellet on hepatic injury induced by pyrazinamide .

异福酰胺胶囊及片剂增加异烟肼和吡嗪酰胺的溶出度检查

Supplement of the Dissolution Test of Isoniazid and Pyrazinamide in Isoniazid , Rifampin and Pyrazinamide Capsules and Tablets

目的评价国产固定剂量复合剂异烟肼利福平吡嗪酰胺/异烟肼利福平（2HRZ/4HR）的抗结核疗效及不良反应。

Objective To evaluate the treatment outcome and si de-effects of national fixed-dose compounds ( 2HRZ / 4HR ) .

结论口服利福平、吡嗪酰胺、静滴复方甘草酸单胺治疗布病安全有效，副作用小，复发率低。

Conclusion To cure brucellosis by taking rifampicin and pyrazinamide orally and potenlin via veinous transfufusion is safe and effective .

利福平联合吡嗪酰胺治疗潜伏性结核感染会引发危及生命的严重肝损

Severe or fatal liver injury in 50 patients in the United States taking rifampin and pyrazinamide for latent tuberculosis infection

浊点萃取-高效液相色谱法同时测定药片与尿样中异烟肼、利福平和吡嗪酰胺

Simultaneous Determination of Isoniazid , Rifampicin and Pyrazinamide in Pharmaceuticals and Human Urine by Cloud Point Extraction High Performance Liquid Chromatography

本部分研究利用尿酸酶抑制剂氧嗪酸和抑制肾脏排泄尿酸的药物吡嗪酰胺，建立一种与人类高尿酸血症天津医科大学博士研究生学位论文更为接近的高尿酸血症动物模型。

In part 2 , a new hyperuricemia model that is more similar to patient is established by oxonic acid and pyrazinamide .

方法：采用含卷曲霉素、结核清、氧氟沙星、复合利福平及吡嗪酰胺等抗结核药物方案对耐多药肺结核患者进行治疗。

Methods : The tuberculosis of multi-drug resistance were treated with capreomycin , pasinizide , ofloxacin , rifampin compound and pyrazinamide for one year .

结核病的一线疗法由每天服用含有4种抗生素的药片组成。这四种抗生素分别是异烟肼、利福平、吡嗪酰胺和乙胺丁醇。

First-line treatment for TB consists of a pill of each of four antibiotics isoniazid , rifampicin , pyrazinamide and ethambutol taken every day .

体外法包括自凝试验、依钙试验、吡嗪酰胺酶试验、水杨苷发酵、七叶苷水解、刚果红菌落试验和毒力质粒。

The vitro methods include autoagglutination test , calcium dependency test , pyrazinamidase test , salicin fermentation , esculin hydrolysis , Congo red colony test and virulence plasmid .