头霉素类
头霉素类-
阴沟肠杆菌临床株对青霉素类、头霉素类、阿莫西林／棒酸以及一、二代头孢菌素有较高的耐药性，主要是由于AmpC酶的存在。
It is often resistant to penicillins , cefoxitin , amoxillin / clavulanic acid and first and second generation cephalosporins because of AmpC enzyme .
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结论：头霉素类抗生素可作为治疗ESBLs菌株引起的重症感染的可选药物，且对我院分离的产ESBLS大肠杆菌和肺炎克雷伯菌，头孢美唑体外活性略优于头孢西丁。
Conclusions : cephamycins can be the alternatives for ESBLs producing strains , and in vitro antimicrobial activity of Cefmetazole against Extended-Spectrum Beta-lactamases producing was higher than that of Cefoxitin in west china hospital .