头孢拉定

超细头孢拉定注射剂的溶解时间缩短，当助溶剂精氨酸的用量减少了29%时，依然可以在较短的时间内完全溶解；

The dissolution time of the ultrafine cefradine injection was shorten , and correspondingly the amount of arginine as a solutizer was reduced by 29 % .

HPLC法监控头孢拉定生产中的酰化反应与萃取操作

Monitoring the acylating reaction and extraction process of cefradine by HPLC

柱前衍生HPLC法同时测定注射用头孢拉定原料中的3种成分

Determination of Three Components in Cefradine for Injection with Precolumn Derivatization HPLC

头孢拉定口服制剂有关物质的HPLC法分析

The analysis of related substance for cefradine and its oral preparation by HPLC

高效液相色谱-离子阱质谱法测定人血浆中的头孢拉定和青霉素G

Determination of Penicillin G and Cefradine in the Human Plasma by HPLC - Ion Trap Mass Spectrometry

建立一种HPLC法快速测定头孢拉定血清浓度。

To establish a simple HPLC column switching method for measuring cefradine in human serum .

HPLC法测定关节腔引流液中头孢拉定的浓度

Determination of the content of cefradine in drainage - fluid from articular cavity by HPLC method

本文对15名新生儿进行了单次静脉滴注头孢拉定50mg／kg后的药物动力学研究，并对8名新生儿进行了尿药浓度测定。

The pharmacokinetics after single intravenous injection of cephradine 50mg / lg was studied in 15 neonates .

目的：建立简便快速的HPLC法，测定髋关节腔引流液中头孢拉定的药物浓度。

Objective : To establish a simple and quick method for determination of the concentration of cefradine in drainage-fluid from articular cavity by HPLC method .

其它抗生素，如头孢拉定、链霉素、青霉素G、强力霉素、乙酰螺旋霉素的实验结果表明它们没有表现出和博莱霉素同样切割DNA的行为。

And then the results about other antibiotics , Cefradine , Streptomycin , Benzylpenicillin , Doxycycline , acetylspiramycin , showed that these antibiotics did not show the same behavior like Bleomycin .

结果：①静滴头孢拉定后1d内出现血尿者10例，占83.33%；

Result : 1 ) The hematuria occured one day after cefradine given by intravenous infusion ( 83.33 % );

目的：研究盐酸山莨菪碱（654-2）对头孢拉定（Cep）注射液稳定性的影响。

AIM : To study the effect of anisodamine hydrochloride on stability of cephradine injection .

目的：考察（25±5）℃下，注射用阿昔洛韦与头孢拉定在0.9%氯化钠注射液（NS）中的配伍稳定性。

Objective : To examine the stability of compatibility of aciclovir sodium for injection and cefradine in normal saline ( NS ) at 25 ± 5 ℃ .

第三组117例，术前1d、手术日及术后1d共3d，每日2次头孢拉定1g静脉注射。

117 patients in group 3 were given Cephradine 1g b. i. d at the day before surgery , surgery day and the day after surgery .

高压液相色谱法测定PVC中DOP含量头孢拉定精氨酸中精氨酸的含量与有关物质在同一高压液相色谱条件下进行检测。

The Determination of DOP in PVC by HPLC A HPLC method was established for the determination of the Arginine and related substances in Cephradine for Injection simultaneous .

用精制7-ADCA生产头孢拉定

Using purification of 7-ADCA to produce Cefradine

方法：18名健康志愿者分别双交叉口服单剂量国产头孢拉定胶囊和进口头孢拉定胶囊各0.5g，用反相高效液相（RPHPLC）法测定血浆中头孢拉定浓度。

Methods : According to crossover design , each volunteer was given a single dose of 0.5 ? g domestic or imported cephradine capsule . The plasma concentrations were determined by RP-HPLC .

采用紫外分光光度法（λmax255±1nm）对5种头孢拉定胶囊进行体外溶出度测定。

The dissolution tests of the five cephradine capsules were determined by UV Spectrophotometry (λ max 255 ± lnm ) .

目的：探讨头孢拉定（CED）所致不良反应的特点，促进临床安全用药。

OBJECTIVE : To discuss the features of adverse drug reaction ( ADR ) induced by cefradine ( CED ) in order to promote the safe drug use in clinic .

为确保头抱拉定的色级在效期内符合药典标准，将主要原料7-ADCA进行精制，利用平行试验的方法，对比头孢拉定的色级及色级稳定性。

To ensure the color of the solution according to CP in its expired time , we purified 7-ADCA , the majority material to produce Cefradine .

剂量与疗程为：安灭菌每次1.2g，头孢拉定每次1g或2g均采用静脉给药，每日34次，每次溶于50ml生理盐水，静脉滴注30min，疗程1014天。

The dosage and therapeutic duration were as follows : AUG 1.2g , CPH 1g or 2g , intravenously , 3 to 4 times per day for 10 to 14 days .

高效液相-串联质谱法测定人血浆中头孢拉定的质量浓度

Determination of Cefradine in Human Plasma by LC-MS / MS Method

奥格门丁与头孢拉定随机对照治疗细菌性感染

Randomized controlled treatment of bacterial infections on augmentin compared with cephradine

头孢拉定注射剂的人体药动学及生物等效性

Pharmacokinetics and bioequivalent study of domestic cephradine injection in healthy volunteers

注射用头孢拉定致血尿不良反应的药理学研究

Study on Hematuria Adverse Drug Reaction Induced by Cefradine for Injection

目的对国产头孢拉定的质量现状进行评价。

Objective To evaluate the quality of cefradine preparations at present .

头孢拉定静滴致血尿18例头孢拉定致血尿原因分析

Analysis of 18 cases with hematuria caused by intravenous drip of cefradine

结论：两种头孢拉定胶囊具有生物等效性。

CONCLUTION : The two cephradine capsules were of bioequivalence .

盐酸山莨菪碱对头孢拉定注射液稳定性的影响

The effect of anisodamine hydrochloride on stability of cephradine injection

解决了注射用头孢拉定中精氨酸的定量控制问题。

Determination of arginine in cefradine for injection was resolved .