培哚普利

血钾在卡托普利组和培哚普利组均有上升（P＜0.005和P＜0.05），血钠水平3组间均无变化。

Plasma K + increased in the groups of captopril ( p < 0.005 ) and perindopril ( p < 0.05 ) but not in the nifedipine group .

结论：培哚普利对DN肾功能的保护作用和其改善内皮细胞功能密切相关。

Conclusion : Perindopril might protect renal function through improving endothelia function during diabetic nephropathy .

B组为治疗组28例，在控制血糖基础上加用培哚普利4mg/d和羟苯磺酸钙3000mg/d（分3次口服）。

Group B of 28 cases as therapy group was treated 3 000 mg / d ( t.i.d. )

慢性低O2高CO2性肺动脉高压大鼠脑超微结构改变与MDA、SOD变化及培哚普利的治疗作用

Changes of the brain ultrastructure and MDA and SOD and effects of perindopril in pulmonary hypertension rats induced by chronic hypoxia-hypercapnia

结论培哚普利可降低EH患者血浆ET、ANP水平，从而有助于降低血压。

Conclusion The influence of perindopril on ET and ANP is correlated to its hypotensive effects in EH patients .

用QRS积分方法评价培哚普利对急性前壁心肌梗死的影响

The Evaluation of Perindopril in the Treatment of Acute Anterior Myocardial Infarction by QRS Scoring System

培哚普利对正常和DM大鼠肢体缺血性血管再生均具有促进作用，这种影响在DM组的表现更为显著。

Treatment of perindopril improved angiogenesis in normal and diabetic ischemic leg . And this effect is more obvious in diabetic rats .

培哚普利可通过降低TGF-β1和MMP-2的表达进而抑制肾性高血压大鼠心肌纤维化的进展。

Perindopril can inhibit progress of RH rat myocardial fibrosis by inhibiting the expression of MMP-2 and TGF - β 1 .

培哚普利对大鼠心肌梗死边缘区Cx43及MMP-7表达的影响

Effect of Perindopril on the Expression of Cx43 and MMP-7 in Infarct Border Zone

培哚普利对心肌梗死大鼠左室重构和心肌组织osteopontin蛋白表达的影响

Effects of perindopril on left ventricular remodeling and myocardial osteopontin expression in rats with myocardial infarction

观察了培哚普利（Per）对心肌梗塞（MI）后心力衰竭（HF）大鼠左室舒张功能的影响。

WC observed the effect of Perindopril ( Per ) on left ventricular diastolic function in rat hearts with cardiac failure induced by myocardial infarction ( MI ) .

在观察期间高血压患者给予培哚普利片4mg，qd。

During observation , hypertensive patients are given to perindopril ( 4mg / day ) .

培哚普利对Duchenne肌营养不良患者左心室功能不全发生、发展的影响

Effect of perindopril on the onset and progression of left ventricular dysfunction in Duchenne muscular dystrophy

目的：探索培哚普利对原发性高血压（EH）合并外周动脉病变（PAD）的影响。

AIM : To study the effect of perindopril in treating essential hypertensive ( EH ) class II accompanied with peripheral arterial disease ( PAD ) .

BNP与急性心肌梗死后左室重构的相关性及培哚普利的影响

The correlation between brain natriuretic peptide and left ventricular remodeling in patients after acute myocardial infarction and the influence of perindopril to BNP

目的观察肾素血管紧张素系统（RAS）对大鼠心肌缺血和缺血再灌注后左心室功能的影响，以及给予氯沙坦和培哚普利干预的结果。

Objective To investigate the effect of RAS on left ventricular function after myocardial ischemia and reperfusion in rats , and the effects of losartan and perindopril .

目的观察培哚普利与氯沙坦联合治疗老年性慢性心力衰竭（CHF）对心室重构与血脑利钠肽（BNP）水平的影响。

Objective To observe the effect of perindopril and losartan on ventricular remodeling and the level of brain natriuretic peptide ( BNP ) in the senile CHF treatment .

氯沙坦及培哚普利对高糖诱导NRK-52E细胞转分化作用研究

Effect of losartan and perindopril on hyperglycemia inducing transdifferentiation in NRK-52E

目的观察培哚普利对老年慢性心力衰竭（CHF）患者循环血中可溶性细胞间黏附分子1（sICAM1）和细胞凋亡抑制因子（FasApo1）水平的影响。

Objective To explore the effects of perindopril on circulating levels of soluble intercellular adhesion molecule-1 ( sICAM-1 ) and Fas / Apo-1 in elderly patients with congestive heart failure ( CHF ) .

本课题的目的在于探讨DM大鼠肢体缺血性血管再生受损的原因以及ACEI-培哚普利在缺血后血管再生中的作用及相关分子通路。

The aim of our study is to investigate the reasons of the impaired angiogenesis in diabetic ischemic hind limbs of rats 、 the role and related molecular mechanisms of ACEI in limbs ' postischemic revascularization .

培哚普利对24h动态血压趋于正常者治疗后降压疗效不明显（P＞0.05），而对符合动态EH诊断标准者，降压疗效显著（P＜0.05或0.01）；

The antihypertensive efficacy was significant in patients with ambulatory EH ( P0 . 05 or 0 . 01 ), while the reduction of blood pressure was less outstanding in patients tending to normal 24 h blood pressure ( P0.05 ) .

【目的】观察培哚普利联合厄贝沙坦对扩张型心肌病（DCM）大鼠的心功能及心肌核因子-κB（NF-κB）活性的影响。

【 Objective 】 To evaluate the effects of combination therapy with perindopril and irbesartan on cardiac function and the activity of NF-kappa B ( NF - κ B ) in the myocardium of rat model of dilated cardiomyopathy ( DCM ) .

两者降低的谷/峰比满意，氯沙坦降压的SBP和DBPT/P比分别为683%和797%，培哚普利分别为684%和798%；

T / P ratio of losartan was 68 3 % for SBP and 79 7 % for DBP , perindopril was 68 4 % and 79 8 % .

在CHF患者中采用小剂量逐渐递增剂量的方式给予培哚普利可明显降低BNP、NE，患者耐受性良好。

Giving perindopril to patients in the heart failure at low dosage initially and gradually increasing to the high dosage could decrease the plasma BNP and NE levels . Patients tolerated it well .

目的了解高血压病（EH）患者血浆可溶性细胞间粘附分子1（sICAM1）和内皮素（ET）浓度的相关性及培哚普利对其的影响。

Objective To measure the relationship between plasma soluble intercellular adhesion molecule 1 ( sICAM 1 ) and endothelin ( ET ) in the patients with essential hypertension ( EH ) and its changes after perindopril treatment .

目的：评价培哚普利对房间隔缺损（ASD）封堵术后右心大小、功能以及抗心律失常的作用。

AIM : To evaluate the effects of perindopril on right cardiac size , its function and antiarrhythmias after transcatheter closure of adult secundum atrial septal defect ( ASD ) .

目的观察培哚普利急性心肌梗死患者（AMI）循环血可溶性细胞黏附分子-1（sICAM-1）和细胞凋亡因子（Fas/Apo-1）水平的影响。

[ Objective ] To explore the effectors of perindopril on circulating levels of soluble intercellular adhesions molecule-1 ( sICAM-1 ) and Fas / Apo-1 in patients with acute myocardial infarction .

培哚普利联合厄贝沙坦调节扩张型心肌病大鼠AT1受体和LaminA表达

Combination Therapy with Perindopril and Irbesartan Regulates the Expression of AT_1 Receptor and Lamin A in a Rat Model of Dilated Cardiomyopathy

结论应用血管紧张素转换酶抑制剂（ACEI）治疗原发性高血压时，宜首选培哚普利。

Conclusion It is suggested that perindopril should be the first choice when angiotensin converting enzyme inhibitor ( ACEI ) is taken into account for the therapy of primary hypertension .

给予EH患者培哚普利片4mg，qd，口服2周后，若收缩压（SBP）>140mmHg或舒张压（DBP）>90mmHg，则增加剂量至4mg，bid。

The EH patients are given perindopril ( 4mg / d ) . After two weeks treatment , if SBP > 140 mmHg or DBP > 90 mmHg , the dosage are increased .