受体蛋白质

受体蛋白质芯片技术的建立及在医药研究中的应用

The Development of Receptor Protein Microarrays and Its Medical and Pharmaceutical Applications

环腺苷酸受体蛋白质

Cyclic amp receptor protein

运用BLAST方法对EST序列进行分析，初步预测该EST序列为光裂合酶／蓝光受体蛋白质家族中一个成员的部分cDNA。

This EST was analyzed by method of BLAST , and the conclusion suggests that the sequence probably be a partial cDNA that can code one of protein family of photolyase / blue light photoreceptor .

脾酪氨酸蛋白激酶（Spleentyrosinekinase，Syk）是一种广泛表达在造血细胞、淋巴细胞、成纤维细胞、血管内皮细胞上的非受体蛋白质酪氨酸激酶，在细胞信号传导中起着重要的作用。

Spleen Tyrosine Kinase ( Syk ) is a non-receptor protein-tyrosine kinase . Its expression has been found in various cells such as the hematopoietic , lymphocyte , fibroblast and vascular endothelial cells .

华盛顿大学医学院的研究者发现，肥胖人群对油腻食物的渴望可能跟他们体内的一种叫CD36的受体蛋白质的指数有关。

But the Washington University School of Medicine researchers found that obese peoples cravings for fatty food may be related to their levels of a receptor called CD36 .

受体蛋白质酪氨酸激酶抑制剂影响兔晶状体上皮细胞增生的研究

Effect of genistein on proliferation of rabbit lens epithelial cell

受体蛋白质酪氨酸激酶和血管内皮生长因子在人胚胎卵黄囊和胎肝中的表达

The expression of KDR and VEGF in yolk sac and liver of human embryo

这些受体蛋白质会干扰神经元之间的连接，从而阻碍染色体提高年青动物的认知能力。

These receptor proteins interfere with neuron communication and thus prevent the sort of synaptic strengthening these young animals need to learn .

据报道，细胞表面的受体蛋白质具有不同立体形态，它们对多糖分子链的构象有特异识别能力从而起不同作用。

It has been reported that the receptor proteins on the surface of the cells have different conformation and show specific recognition capability to the chain conformation of polysaccharides .

究竟是受体蛋白质的变性还是膜脂质的相变造成高亲和力受体的消失，尚需进一步研究。

Whether heat inactivation of the high affinity receptor is the result of denaturation of the receptor protein or that of the phase transition of membrane lipids remains a problem for further study .

例如，将药物分子固定在纳米级高分子乳液微球表面，利用亲和微球的生物惰性和高比表面积等优点，高效的从生物组织液中识别、分离、纯化药物受体蛋白质。

For example , the affinity microspheres hold the bio-inert and high surface area can be used for identification , separation and purification of drug receptor from biological tissue by immobilizing the drug molecules on its surface .

危重病患者血浆可溶性肿瘤坏死因子受体与蛋白质分解代谢的关系及其预后价值

Correlation between soluble tumor necrosis factor receptor and protein catabolism and its value in predicting prognosis in critically ill patients

半定量反转录聚合酶链反应和免疫印记法测定孕激素受体mRNA和蛋白质表达；

The expression of progestogen receptor ( PR ) mRNA and protein was measured by semi quantitive reverse transcription polymerase chain reaction ( RT PCR ) and Western blot .

结论大鼠海马组胺H2受体mRNA和蛋白质表达的变化对海马的生理功能有一定的影响。

Conclusion The change of protein and mRNA expression of histamine H_2 receptor in rat hippocampus induced by the snake venom may affect the physiological function of rat hippocampus .

孕酮不影响孕激素受体mRNA和蛋白质表达，但可增加c-fos，c-junmRNA表达，分别为5.4%，15.3%，35.5%和7.2%，20.1%，40.3%。

The expression of RP mRNA and protein were not affected by progesterone , but the expression of c fos and c jun mRNA were increased by progesterone , the expressions were 5.4 % , 15.3 % , 35.5 % and 7.2 % 20.1 % , 40.3 % respectively .

H1受体mRNA和蛋白质表达的改变对大脑的生理功能有一定的影响，可能是该蛇毒致脑功能障碍的分子基础之一。

The change of protein and mRNA expression of histamine H_1 receptor in rat hippocampus induced by the snake venom may affect the physiological function of rat brain , which may be one of molecular mechanisms that involved in function disorders of rat brain caused by the snake venom .

精神分裂症患者大脑皮质尼古丁受体亚单位蛋白质水平的改变

Nicotinic Receptor Subunit Proteins in the Cortex of the Patients with Schizophrenia

重组人肿瘤坏死因子受体-Fc融合蛋白质控方法和标准的研究

Study on methods and requirements for quality control of recombinant human tumor necrosis factor receptor Fc fusion protein

这样的受体可以是蛋白质、酶、膜通道或外来病原体的一个区域。

Thus a receptor may be a protein , enzyme , membrane channel , or a region of a foreign pathogen .

通过在模拟中引入外力、简谐势和减少蛋白质构象空间自由度等技术使得模拟的时间范围比常规动力学宽，因而可以模拟配体和受体结合、蛋白质的异构效应等生物现象。

By introducting techniques of external force , simple harmonic potential and the reduction of protein conformational freedom and so on , simulated time scale is more than conventional dynamic methods , and thus can simulate the ligand and receptor binding , heterogeneous effects of protein and other biological phenomena .

五步蛇毒对大鼠脑区海马组胺受体H2mRNA和蛋白质表达的影响

The effects of Agkistrodon Acutus venom on protein and mRNA expression of histamine H_2 receptor in rat hippocampus

NMDA受体信号复合体中蛋白质的相互作用

Protein-protein interactions in NMDA receptor signaling complex

核受体组成一个蛋白质大家族，它们作为配体调节的转录因子，能够直接与DNA结合，调节下游靶基因的表达。

The nuclear receptors constitute a large family of proteins and can be considered as ligand-inducible transcription factors , which can bind directly to DNA and regulate expression of downstream target genes .

结果5-羟色胺受体-1a基因的蛋白质和mRNA水平随着IFN诱导时间的增加而下降，但能在IFN撤除后得到一定程度的恢复；

Results The time-dependent decreases of protein expression and mRNA level of serotonin receptor-la were observed . Partial recovery was observed following IFN withdrawal .

人参皂甙Rb1和Rg1对小鼠中枢神经递质受体和脑内蛋白质合成的影响

Influence of ginsenoside rb_1 and rg_1 on some central neurotransmitter receptors and protein biosynthesis in mouse brain

分子生物学研究阐明中枢神经系统中抑制性神经递质γ-氨基丁酸A型（GABAA）受体由不同的蛋白质亚单位组合构成。

Molecular biological studies elucidate the inhibitory neurotransmitter GABA_A receptor consists of different protein subunits in central nervous system . So far 15 subunits , i.

结论心肺复苏后大鼠延髓心血管中枢NMDA-2A、NMDA-2B两型受体在mRNA及蛋白质水平上发生了显著上调，心肺复苏后大鼠脑水肿形成可能与NMDA受体上调有关。

Conclusion mRNA and protein level of rats ' NMDA-2A and NMDA-2B in medulla oblongata cardiovascular center after CPR are higher markedly , and rats'cerebral edema after CPR was associated with the regulation of NMDA receptors .

其中，NMDA受体信号复合体中蛋白质-蛋白质的相互作用及其调控机制的阐明，对于深入了解神经发育、突触可塑性、兴奋性毒性等生理病理的分子机制有重要意义。

Elucidating the roles and regulation mechamisms of the dynamic protein-protein interactions in NMDA receptor signaling complex serves critical functions in further understanding the molecular mechanisms of multiple physiological and pathological events including neuronal development , synaptic plasticity , learning , memory and diverse neurological disorders resulting from excitotoxicity .

运用双杂交系统探寻与内皮素A型受体相互作用的蛋白质

Screening proteins interacted with endothelin type A receptor by yeast two hybrid system

其他干细胞的培养、保存、测定、转化技术以及与疾病有关的专利大部分属于美国的大学和生物工程公司。干细胞主要研究领域集中在受体、酶及蛋白质基因功能的确定；

Culture , preservation , determination , transformation and patent related to disease of stem cells mostly belonged to American Universities and biological engineering companies .