免疫球蛋白超家族

细胞间粘附分子1（ICAM1），又名CD54，是免疫球蛋白超家族的成员之一，是一种重要的细胞表面粘附因子。

Intercellular adhesion molecule-1 ( ICAM-1 , CD54 ), which belongs to the immunoglobulin superfamily , is one of the important adhesion molecules on the cell surfaces .

该分子的序列和免疫球蛋白超家族（IgSF）的成员具有同源性，提示了它作为一个粘附分子的功能。

The molecule has the homologous sequence with Immunoglobulin superfamily ( IgSF ) members , which suggests its functions as a adhesion molecules .

L1细胞粘附分子（L1celladhesionmolecular，L1CAM）属于神经细胞粘附分子，是属于免疫球蛋白超家族的Ⅰ型跨膜糖蛋白。

L1 cell adhesion molecular is a type ⅰ membrane glycoprotein of immunoglobulin superfamily .

基因测序结果表明，该cDNA具有独立的开放阅读框架，编码1个由344个氨基酸残基构成的可溶性蛋白分子，属于免疫球蛋白超家族成员。

DNA sequencing analysis showed that the cDNA had an open reading frame encoding 344 amino acid residues without transmembrane domain and belonged to immunoglobulin superfamily .

免疫球蛋白超家族分子CD54在各种恶性淋巴增殖性疾病的表达

Expression of immunoglobulin supergene family adhesion molecules ( CD45 ) in malignant lymphoproliferative disease and its clinical implications

CD28分子是表达于T淋巴细胞表面的跨膜糖蛋白，参与介导T细胞活化所需的协同刺激信号，属于免疫球蛋白超家族。

CD28 , a cell surface glycoprotein , predominantly expressed on T cells , belongs to the Ig superfamily and provides critical co-stimulatory signals .

在Profound蛋白数据库内初步检索得该蛋白为免疫球蛋白超家族的一员，Western-blot确认其为β2-MG。

Searching in the Profound protein database , we found the protein was a member of the immunoglobulin superfamily . Through western-blot , we identified it as β 2-MG .

CD147是免疫球蛋白超家族成员之一，在正常组织中有着广泛的分布。

CD147 is a member of the immunoglobulin superfamily ( IGSF ) . It exists in many normal tissues widely .

杀伤细胞抑制性受体（KIR）属于免疫球蛋白超家族成员I型跨膜蛋白分子，主要表达于人NK细胞和某些T淋巴细胞。

Killer cell inhibitory receptors ( KIR ) are members of the immunoglobulin superfamily ( Ig SF ) and transmembrane molecules type I expressed on human natural killer cells and some T lymphocytes .

CD83分子是一个分子量约为40–45kDa大小的糖蛋白，属于免疫球蛋白超家族成员[1,2]，其功能还不是完全清楚。

Objective : The glycoprotein CD83 has a molecular mass of 40 – 45 kDa and belongs to the Ig superfamily . The function of CD83 remains largely unknown .

细胞间黏附分子-1（Intercellularadhesionmolecule1，ICAM1或CD54）是免疫球蛋白超家族成员及跨膜糖蛋白，也是淋巴细胞功能相关抗原-1（LFA1）的主要配体，涉及细胞分化、黏附及迁移。

Intercellular adhesion molecule-1 ( ICAM-1 , CD 54 ) is a member of immunoglobulin superfamily ( IGSF ), a transmembrance glucoprotein , and the major ligand of lymphocyte function associated antigen-1 ( LFA-1 ), involved in differentiation , adhesion and migration of cells .

血管细胞粘附分子一1（VCAM-1）是一种属于免疫球蛋白超家族成员的细胞粘附分子，其配体主要是整合素家族的α4β1/VLA一4（非常晚出现抗原一4）。

Vascular cell adhesion molecule 1 ( VCAM - 1 ) is a member of immunoglobulin superfamily . The principal ligand for VCAM - 1 is integrin α 4 | β 1 / VLA - 4 ( very late antigen 4 ) .

免疫球蛋白超家族黏附分子在淋巴管和不同血管内皮细胞的表达

Expression of adhesion molecules of immunoglobin super family on lymphatic endothelial cells and different vascular endothelial cells

人类免疫球蛋白超家族一个新成员：α-1B糖蛋白前体基因的克隆和分析

Cloning and Analysis of Human α - 1B Glycoprotein Precursor Gene : A Novel Member of Human Immunoglobulin Superfamily

进一步，对质膜蛋白质数据集进行了功能分析，发现了10个可能的免疫球蛋白超家族成员。

Then , the function of plasma membrane proteins was analysis , and 10 hypothetical plasma membrane proteins may belong to the immune globulin superfamily .

免疫球蛋白基因超家族（IgSF）包括很多成员，它们都参予免疫应答及免疫调节。

Abstract Immunoglobulin gene superfamily ( IgSF ) include many members which take part in immune response and immunoregulation .

ALCAM主要表达在白细胞和胸腺上皮细胞，属于免疫球蛋白基因超家族的成员，是淋巴细胞抗原CD6的配基。

ALCAM belongs to immunoglobulin gene superfamily . It is mainly expressed on leucocyte and thymic epithelial cell and is the ligand of CD6 lymphocyte antigen .