免疫损伤

组织相容性抗原CD45RO肿瘤坏死因子在桥本氏甲状腺炎和亚急性甲状腺炎的表达与免疫损伤的关系及临床意义

The Relationship Between The Expression of HLA-DR , CD45RO , TNF - α and Immune Injury in HT and SAT and Its Clinical Significance

提示除了HBV抗原抗体复合物所致体液免疫损伤机制外，亦应考虑肾组织感染HBV导致的细胞免疫机制参与了IgA肾病的发病。

The results suggested that in addition to the humoral immune injury mediated by HBAg - HBAb immune complex , the cellular mechanism mediated by HBV originating from renal cells in situ may also involved in the pathogenesis of IgAN .

结论：重组人肝再生增强因子可预防免疫损伤性肝纤维化的形成。

Recombinant human augmenter of liver regeneration may prevent the formation of immuno complex induced liver fibrosis .

乌梅丸对免疫损伤性大鼠肝纤维化α1（Ⅰ）型前胶原mRNA表达的影响

Effect of Wumei pills on expression of α _1 ⅰ procollagen mRNA in hepatic fibrosis rats

RA关节滑膜内浸润的炎症细胞中以T细胞最多，由T细胞过度激活引起的免疫损伤，加重了滑膜的炎症反应和滑膜组织增生。

The immune damage which is brought by excessive activated T cell aggravates inflammatory reaction and synovial hyperplasia .

大量研究表明免疫损伤是DN发病过程中重要的因素之一。

Numerous studies show that the damage mechanism of DN involved in the immune pathogenesis .

研究结果提示，DC-SIGN也是肾小管间质早期炎症的启动参与因素，其介导DC可能也参与了人肾炎肾小管间质的免疫损伤机制。

DC-SIGN may mediate DC onthe renal tubular interstitial injury induced by an immuno-inflammatory response .

STZ诱导的糖尿病大鼠视网膜的免疫损伤

Immunological Injuries on the Retina of STZ-induced Diabetic Rats

结果墨旱莲水煎剂显著提高免疫损伤小鼠的DTH和血清溶血素抗体水平。

Results EP enhance DTH and hemolysin antibody concentration of immunity damaged-mice , significantly .

重症及危重症甲型H1N1流感患者存在明显的细胞免疫损伤。

The patients with severe and critical influenza A ( HINI ) were found having damage of the cellular immunity markedly .

吡格列酮对STZ诱导的糖尿病大鼠肾脏和骨骼肌免疫损伤的治疗作用

The Effects of Pioglitazone on the Autoimmune Injuries to the Kidneys and the Skeletal Muscle in STZ-induced Diabetic Rats

目的：观察青芪散对免疫损伤性小鼠自然杀伤细胞（NK细胞）和白细胞介素-2（IL-2）的影响，并探讨其机制。

Objective : To study the effect of Qingqi granules on natural killer cells ( NK ) and interleukin-2 ( IL-2 ) of mice with immunological liver injury .

有证据表明，活性氧（reactiveoxygenspecies，ROS）参与了胰岛β细胞自身免疫损伤，是自身免疫性糖尿病发病的重要原因之一。

Reactive oxygen species ( ROS ) is involved in autoimmune destruction of islet β cells , which has been proven to be an important underlying pathogenesis for insulin dependent diabetes mellitus ( ID-DM ) .

抑肝纤对大鼠实验免疫损伤性肝纤维化阻断作用的研究目的探讨干扰素α（IFNα）预防肝纤维化的作用机制。

Preventing Hepatic Fibrosis From Experimental Rates Immuno & damaged Objective To investigate the mechanism of inter fe ron - α ( IFN α) in preventing hepatic fibrosis in rat experimental model .

结论：多数SAA存在造血干、祖细胞的缺陷且可能是由免疫损伤机制引起；

Conclusion : In the majority of SAA patients , the hematopoietic stem cells or progenitors were defective perhaps caused by immune damage ;

环孢素（cycloporine，CsA）属于钙调神经酶抑制剂，通过减少急性排斥反应率和早期免疫损伤发生，对肾移植成功整体上有革命性的影响。

Cyclosporine ( CsA ), known as calcineurin inhibitor , has a revolutionary effect on the overall success of renal transplantation through reduction in acute rejection rates and early immunologic injury .

目的：探讨急性脑梗死（ACI）中医辨证分型与细胞因子介导的免疫损伤的关系。

Objective : To investigate the relationship between immune damages mediated by cytokines and traditional Chinese medical syndrome differentiation and typing in patients with acute cerebral infarction ( ACI ) .

结论病毒性肝炎患者IL-6和TNF-α的测定能反映机体免疫损伤状况，对判断患者病情和预后有一定的临床价值。

Conclusion The detection of serum levels of IL-6 and TNF - α in patients with chronic hepatitis B may disclose immunological injury to the body and it is of certain value in judging the conditions of the patients and prognosis .

特异性神经元抗一Hu抗体是PNSNS的特异性、敏感性指标，推测在神经元的免疫损伤机制中具有重要作用。

Specific neuronal anti-Hu anti-body is a specific and sensitive marker in detecting paraneoplastic syndrome of nervous system ( PNSNS ) and play a important role in immune disorders ;

TCE对肾脏的作用机制不同于DNCB，TCE不单纯是致敏剂，也是免疫损伤剂。

In the mechanisms of renal injury , TCE is different from DNCB ; TCE is not only a simple allergic agent , but also is immune damage agent .

初步认为MLA有助于观察肝炎病情转归和探讨细胞免疫损伤的机制。

Our study revealed that MLA seems to be helpful to observe the outcome of hepatitis and investigation of the mechanism of cellular immune injury .

PDC-E2被认为是最可能的诱导胆管上皮产生自身免疫损伤的靶抗原。

PDC-E2 is considered to be the most possible target antigen that mediated the damage of the intrahepatic bile ducts .

结论ApoEε4基因表达低的肝脏炎症反应重，IFN-γ参与免疫损伤，ApoEε4可能对外周白细胞膜表面的IFN-γR1的表达具有调控作用。

Conclusion The liver inflammation was severe in patients with low expression of ApoE ε 4 , the ApoE ε 4 may regulate the IFN - γ R1 expression on the peripheral leucocytes .

结论在DN的发生过程中存在着以AECA介导的免疫损伤，可能是DN发生发展的一个重要因素。

Conclusion The immunity damaged mediated by AECA was exist in the develop or arise through evolutionary processes of DN , and it may be a important factor for the development of DN .

提示：AITD患者可伴有肾脏远曲小管细胞的免疫损伤。

The THP excretion was not correlated with thyroid function and patients with AITD may complicated with the immunological damage of the distal convoluted tubule of kidney .

结论NOS、NO及TNF参与了胸膜组织免疫损伤及胸液渗出过程，检测胸液中NOS、NO及TNF含量有助于胸水性质的诊断。

Conclusion The NOS , NO and TNF may involve in the immune damage of pleural tissues and the process of pleural effusions . The measurement of NOS , NO and TNF in pleural effusions were helpful in differential diagnosis of pleural effusions .

结论ICAM1和HLAA，B，C共同参与介导乙型肝炎肝细胞的免疫损伤过程；ICAM1/HLAA，B，C双阳性肝细胞可能是CTL发挥有效细胞毒作用的靶细胞。

Conclusion ICAM 1 is involved in mediating immune damage of hepatocytes together with HLA A , B , C in viral hepatitis B. ICAM 1 / HLA A , B , C double positive hepatocytes may be the target cells attacked by the cytotoxic T lymphocyte ( CTL ) .

ConA诱导的肝炎主要通过快速活化多克隆T细胞包括为CD4+T细胞、CD8+T细胞和NKT细胞来实现自身免疫损伤。

ConA-induced hepatitis , mainly through the rapid activation of polyclonal T cells were mainly CD4 + T cells , CD8 + T cells and NKT cells to realize their own immune injury .

因此，肠道共生菌参与PR8感染诱导的小肠免疫损伤。

So , commensal intestinal bacteria are involved in the small intestinal injury induced by influenza virus infection . 4 .

本实验首次揭示了Th1和Th2功能亚群的失衡在辐射所致免疫损伤中的重要作用，为探索辐射免疫损伤的防治措施提供了新的思路。

Above-mentioned results first revealed an important role of the imbalance of Th1 / Th2 function subpopulations in radiation-induced immune injury and provided a better insight into the new strategies for prevent and treatment measures of immune injury by irradiation .