克隆性

对急性B淋巴细胞白血病的克隆性、多样性及对化疗药物敏感性的探讨

Study on clonality , diversity and sensitivity to chemotherapy drugs in acute B-lymphoblastic leukemia

X染色体随机失活类型的分析不但为克隆性分析提供了可能性，而且可以显示同一疾病不同个体的易感性。

Random inactivation of one X-chromosome in somatic cells offers a probability for the clonality analysis .

弥漫性大B细胞淋巴瘤克隆性基因重排检测研究

Detection of gene rearrangement of immunoglobulin heavy chain in diffuse large B-cell lymphoma

克隆性基因重排检测用于诊断B细胞淋巴瘤微小病灶

Clonal Gene Rearrangement for the Detection of Minimal Residual Lesions in B Cell Lymphoma

目的：多发性骨髓瘤（multiplemyeloma.MM）是一种浆细胞克隆性增殖的恶性疾病。

Objective : Multiple myeloma ( MM ) is presently an incurable malignant plasma cell tumor .

石蜡包埋B细胞性恶性淋巴瘤组织克隆性免疫球蛋白重链基因重排检测研究

Study on Detection of Clonal Immunoglobulin Heavy Chain Gene Rearrangement in Paraffin-embedded Tissues from B-cell Lymphomas

克隆性免疫球蛋白重链基因重排检测可以作为诊断恶性B细胞性非霍奇金淋巴瘤的有效分子标志。

Clonal immunoglobulin heavy chain gene rearrangement can be used as a effective diagnostic molecular marker for B-NHL .

肝细胞癌和癌旁组织中乙型肝炎病毒DNA整合的克隆性

Integration of hepatitis B virus DNA in liver tissues from patients with hepatocellular carcinoma and liver cirrhosis

多发性骨髓瘤（MM）是来源于B淋巴细胞的恶性肿瘤，以终末分化的浆细胞的克隆性增生为显著特征。

Multiple myeloma ( MM ) is characterized by cloning proliferation of terminally differentiated plasma cells .

目的探讨血清游离DNA含量及其克隆性重排基因检测在淋巴系统恶性肿瘤诊断中的价值。

Objective To evaluate the diagnostic significance of detecting serum-DNA concentration and clonal gene rearrangement in lymphogenous malignant patients .

急性白血病（acuteleukemia，AL）是一种造血干细胞恶性增殖的克隆性疾病。

Acute leukemia ( AL ) is a clone disorder that characterized by haemopoietic stem cells malignancy proliferative .

非小细胞肺癌患者T细胞受体Vβ表达和克隆性研究

Study on clonal expression of T cells bearing dominant TCR V β in non-small-cell lung cancers

系列PCR方法检测淋巴细胞白血病克隆性基因重排的选择应用

The choice of a serial PCR method in the detection of clonality gene rearrangement in lymphoblastic leukemia patients

多发性骨髓瘤（MM）是骨髓内异常浆细胞克隆性增殖性疾病。

Multiple myeloma ( MM ) is a B-cell neoplasma characterized by clonal expansion of malignant plasma cells in the bone marrow .

应用TCRVβ基因谱分析血液病与免疫性疾病的T细胞克隆性

T Cell Clonality in Hematological Disease and Autoimmune Disease Using Analysis of TCR V β Gene Repertoire

淋巴瘤白血病患者TCRVβ亚家族T细胞的分布及其克隆性

The distribution and clonal expansion of TCR V β subfamily T cells in patients with lymphoma leukemia

急性髓系白血病患者外周血T细胞TCRVβ亚家族表达及克隆性增殖分析

Expression and Clonal Proliferation of TCR V β Subfamilies of Peripheral T-cells in Acute Myeloid Leukemia Patients

基因重排：TCRβ1克隆性重排。

Clonal rearrangement of genes : TCR β 1 + .

一步及半巢式PCR检测石蜡包埋B细胞淋巴瘤组织克隆性IgH重排的比较

Detection of immunoglobulin heavy-chain gene rearrangement of formalin-fixed and paraffin-embedded B cell lymphoma tissue by single-step and semi-nested polymerase chain reaction

目的：建立基于克隆性分析技术的B和T淋巴细胞产生的抗原受体分子基因重排检测技术，探讨B淋巴细胞免疫球蛋白及T淋巴细胞受体基因重排在恶性淋巴瘤临床诊断中的应用。

AIM : To establish a way to detect the gene rearrangements of IgH and TCR and to assess the application of the detection technique in the diagnosis of malignant lymphoma .

TCRβ克隆性基因重排分析在NHL诊断中的应用

Application of clonal TCR - β gene rearrangement in diagnosis of non-Hodgkin lymphoma

结论尽管从蛋白角度分析该MM细胞似乎是寡克隆性的，但是基因序列分析的结果表明其恶性克隆仍然是单克隆性起源。

Conclusion Despite the oligoclonality of MM cell , the sequencing results of 3 IgH genes showed that all the malignant cells were monoclonal origin .

无IgH和TCRγ克隆性重排。

No clonal rearrangement in both IgH and TCR γ genes was detected .

目的探明PCR克隆性基因重排检测（基因诊断）在NHL诊断中的意义。

Objective To explore the significance of detection of clonal gene rearrangement in diagnosis of non-Hodgkin 's lymphoma ( NHL ) .

目的：初步阐明急性B淋巴细胞白血病（B鄄ALL）免疫球蛋白重链（IgH）基因克隆性重排的发生及其异质性。

To document the occurrence and heterogeneity of clonal rearrangements of immunoglobulin heavy chain ( IgH ) gene in acute B lymphoblastic leukemia ( B-ALL ) .

背景白血病（leukemia）是造血干细胞克隆性增殖的肿瘤性疾病，严重威胁人类健康和生命。

Background : leukemia is a malignant desease from the hemopoietic stem cell ( HSC ), it seriously threatens the health and lives of human beings .

MDS的细胞遗传性克隆性异常可以指导中医的辨证分型及临床治疗。

MDS clonal cell genetic abnormalities can guide the dialectical traditional Chinese medicine classification and clinical treatment .

目的：了解B细胞淋巴瘤白血病（LL）患者TCRVβ亚家族T细胞的分布及其克隆性。

Aim : To investigate the distribution and clonal expansion of TCR V β subfamily T cells in patients with B cell lymphoma leukemia ( LL ) .

〖研究背景〗真性红细胞增多症（PV）是由于多潜能造血干细胞发生突变而引起的恶性克隆性疾病。

BACKGROUD : Polycythemia vera ( PV ) is a malignant clonal hemotopoietic disorder resulted from the mutation of multipotent hematopoietic stem cells .

目的：探讨原发性睾丸淋巴瘤克隆性IgH基因重排的检测方法。

Purpose To investigate the clonality of IgH gene rearrangement in primary testicular lymphoma .