翻译起始

蛋白翻译起始因子C2在原发性肝细胞肝癌中表达的意义

Significance of translation initiation factor C_2 expression in hepatocellular carcinoma tissues

基于支持向量机识别真核生物DNA中的翻译起始位点

SVM based recognition of translation initiation sites in eukaryotic DNA

支链氨基酸对mRNA翻译起始的调控作用

Regulation of mRNA Translation Initiation by Branched - Chain Amino Acids

mRNA翻译起始区的结构改变对几个外源基因翻译的影响

The Mutation of mRNA Translation Initiation Region Influences Gene Translation

实验结果表明基于数据优化法的SVM分类器在翻译起始位点的辨识上可获得比其他判别方法更好的效果。

Experiment results show that data optimization based SVM is better than other methods .

对于脊椎动物以及人类的mRNA序列，运用核糖体扫描模型预测其翻译起始位点得到了很好的预测率。

By using of ribosome scanning model , high accuracy in vertebrates and human mRNA sequences is obtained .

coli和真核生物Yeast翻译起始区域的显著差异；

The remarkable difference between prokaryote E. coli and eukaryote Yeast at translation region is reflected .

日本血吸虫真核生物翻译起始因子2α亚基全长cDNA的克隆与功能分析

Cloning and function analysis of full-length cDNA sequence of Schistosoma japonicum eukaryotic translation initiation factor 2 alpha subunit

mRNA翻译起始区二级结构优化提高（R）-羰基还原酶的表达及催化效率

Improved expression and catalytic efficiency of ( R ) - carbonyl reductase in Escherichia coli by secondary structure optimization of mRNA translation initiation region

蛋白翻译起始因子C2在结、直肠癌中表达的意义

Expression significance of translation initiation factor C2 gene in colorectal cancer tissue

蛋白翻译起始因子C2在消化道肿瘤中的表达和意义

The Expression and Significance of Protein Translation Initiation Factors C2 in Digestive System Neoplasms

C2基因是在肝癌研究过程中克隆出的人源性真核细胞蛋白翻译起始因子。

C2 gene is a new cloned human eukaryotic translation factor during the study of hepatic carcinoma .

本研究利用PCR技术将人单核细胞趋化蛋白－1基因（MCP－1）5′端翻译起始区进行优化改构。

The present study was designed to optimize the 5 ′ translation initiation region of human monocyte chemoattractant protein-1 ( MCP-1 ) .

真核生物翻译起始因子5A的结构与功能研究进展

Structure and function of eukaryotic initiation factor 5A : recent progress in research

蛋白翻译起始因子C2在肝癌、胃癌中的表达与分布

The expression and distribution of protein translation initiation factors C2 gene in hepatocellular carcinoma and gastric cancer tissue

目标起始密码子多态性（SCoT）：一种基于翻译起始位点的目的基因标记新技术

SCoT : A Novel Gene Targeted Marker Technique Based on the Translation Start Codon

结论针对β-catenin翻译起始部位结构的反义寡核苷酸，有望成为HCC反义基因治疗的新选择。

Conclusion . The antisense oligonucleotides complementary to β - catenin translation initial site , may become a potential alternative for antisense gene therapy of HCC .

翻译起始区二级结构对荧光素酶基因在COS-7细胞中表达效率的影响

Effects of Translation Initiation Region Secondary Structure on Expression of Luciferase Gene in COS-7 Cells

植物翻译起始共有序列与动物体中的Kozak序列具有相同的功能，能够加速mRNA的翻译起始。

Plant mutual sequence of starting translation and Kozak sequence in animals have the same function namely accelerate translation starting of mRNA .

当上游的翻译起始密码由ATG突变为ATC时，内部翻译起始序列几乎失去翻译起始功能。

When the ATG of the upstream gene was changed to ATC , no translation occurred from the internal TIR .

目的根据翻译起始调控的定量理论及利用翻译增强子序列，提高人干扰素α1型变种IFNα1C基因的原核表达。

Objective To increase prokaryotic expression level of IFN α 1C gene through the quantitative theory of translational control and the translational enhancer sequence .

真核细胞翻译起始因子4E在子宫内膜癌中的表达及意义

Eukaryotic Translation Initiation Factor 4e Expression in Endometrioid Adenocarcinoma and Its Significance

1个基因与翻译起始因子eIF成员有高的同源性。

One gene is highly homologous to the translation initiation factor eIF .

由于碱性蛋白酶mRNA翻译起始区的复合二级结构和低起始强度以及依赖链霉素突变核糖体高级结构的改变，使依赖链霉素突变核糖体不能翻译碱性蛋白酶mRNA。

These results suggest that Str-D ribosomes could not translate apr mRNA because of the secondary structure complex , low initiation strengh of apr mRNA , and alteration of the higher order structure of the Str-D ribosomes .

全长单链抗体基因包括一个T7启动子和一个翻译起始序列（Kozak序列）。

The full-length scFv DNA contains a T7 promoter and a translation initiation signal ( Kozak sequence ) .

结合位置权重矩阵（PWM，positionweightmatrix）和开放阅读框架（ORF，Openreadingframe）的长度分布特征建立了简单的方法识别翻译起始位点，此方法能很好地区分上游AUG和TIS。

Based on the position weight matrix ( PWM ) and length distribution of open reading frame ( ORF ), a simple method for predicting translation initiation sites is presented . It can identify TIS from upstream AUGs easily .

在碱性蛋白酶mRNA翻译起始区有一个复合二级结构，用体外突变方法破坏其中一个，翻译效率提高8.2倍。

There is a secondary structure complex at the translation initiation region of apr mRNA . When one of the secondary structure was destroyed by site directed mutagenesis , the translation efficiency was enhanced by 7.3 to 9.1 folds .

通过RT-PCR的方法确定OsGCS基因的转录起始位点可能位于翻译起始位点（ATG）上游211bp处。

The putative transcription start site ( TSS ) confirmed by RT-PCR was located 211 bp upstream of the translation start codon ' ATG ' ( Fig.5 ) .

目的探讨Ki-67基因翻译起始区反义肽核酸对人肾癌细胞Ki-67基因表达及生长的影响。

Objective To investigate the influence of antisense peptide nuclear acids of Ki-67 gene translation initiator on the growth of human renal carcinoma cell strain and the Ki-67 protein expression .

MFC在真核生物蛋白质翻译起始过程中起重要作用，主要参与蛋白质重起始过程中二元复合物（TC）的招募和AUG起始密码子的正确识别。

MFC is involved in recruitment of the ternary complex ( TC ) and recognition of the correct start codon . It plays a critical role in the process of translation initiation .