反式作用

珠蛋白基因的转录受多种因素的影响，其调控主要通过结构基因近端和远端的顺式作用元件，红系特异的和普遍存在的反式作用因子发挥作用。

The transcription regulation of globin genes is mainly related to local and distal cis-acting elements and cellular trans-acting factors .

降血脂药物（DEHP）对酰基CoA氧化酶基因反式作用因子的影响

The Effect of Hypolipidemic Drug ( DEHP ) on the Trans-acting Factor ( s ) for Gene of Acyl-CoA Oxidase

利用人工设计反式作用小RNA进行细菌基因沉默的研究

Specific Gene Silencing by Artificial Trans-encoded sRNA in Bacterial

已有研究表明DNA顺式作用元件与反式作用因子之间的相互作用是染色质重塑和基因转录调节的基础。

Present studies indicate that the interactions between trans-acting factors and corresponding DNA cis-acting elements are the basis of chromatin remodeling and gene transcription regulation .

HBX作为反式作用因子，不能直接和双链DNA结合，而是通过蛋白与蛋白间的相互作用行使功能，可以调节转录、引起DAN修复蛋白质失活以及激活信号转导通路。

As a transcriptional activator , HBx functions through interaction between protein and protein , instead of binding directly with DNA .

肌钙蛋白I2辅助活化多种核受体的反式作用

Troponin I 2 Co-activating Transactivation of Multiple Nuclear Receptors

NMD作用的顺式调控元件选择性剪接过程受多种顺式作用元件和反式作用因子相互作用调节。

The alternative splicing is regulated by the interaction between diverse cis-acting elements and trans-acting factors .

转录因子（Transcriptionfactor）是一大类反式作用因子，可以通过结合特异的DNA序列即转录因子结合位点（Transcriptionfactorbindingsite，TFBS）而改变靶基因的转录活性。

Transcription factors , a large group of trans-acting factors , can change the transcriptional activity by binding specific DNA sequence , transcription factor binding site ( TFBS ) in the cis-regulatory regions of target genes .

一旦有乙酰化的存在，DNA的构型发生松解，转录因子得以与核小体中相应的顺式作用原件结合，同时募集相应反式作用因子，启动基因转录。

The DNA configuration was loosened in the existence of acetylation , then transcriptional factors could be combined to the corresponding cis-acting original body in nucleosomes , and in the mean time , corresponding trans-acting factors was recruited , then gene transcription can be started .

有研究表明血管生成素体外可与血管生成素结合元件（Angiogenin-BindingElement，ABE）结合并促进ABE的启动子活性，说明血管生成素可能扮演反式作用因子的角色。

An angiogenin-binding element ( ABE ) has been identified in vitro and exhibited angiogenin-dependent promoter activity in the luciferase reporter system , indicating that angiogenin may serve as a trans-acting factor .

它是细胞增殖必不可少的即刻早期基因，是一种调控基因转录的反式作用因子，其表达产物是细胞增殖信号转导的必需因子，也是细胞从G0／G1期进入S期的驱动因子。

It is one of immediate-early gene indispensable to cell proliferation , and its product is a trans-acting transcription factor that drives the cells from G0 / G1 phase into S phase .

文章综述了cbs基因的结构特点、调控cbs基因表达的上游顺式反应元件和反式作用因子、CBS蛋白的结构及缺失、突变等方面的研究进展。

This article reviews the latest progress in the study of CBS and its cis-acting element , trans-acting-factor involved in the regulation of gene expression , and the structure , deletion , mutation of CBS .

热休克因子（HSF）是转录水平上hsp表达调控的重要反式作用因子，对HSF的深入研究有助于对hsp转录活化调控机制的进一步了解。

Heat shock factors ( HSF ) are major trans-factors for hsp transcriptional regulation . The study of its regulation mechanism will lead to a better understanding of their biological functions .

CBF4转录激活因子是一类受干旱特异诱导的反式作用因子。

CBF4 transcription activator is one kind of trans factors , which is induced by drought .

结论大鼠c-Jun蛋白和线粒体腺苷酸转位酶在酵母细胞内与大鼠GST-P增强子GPE核心序列结合，可能是作用于GPE的反式作用因子。

Conclusions Rat c Jun and mitochondrial adenine nucleotide translocase can bind to the GPE ⅰ core sequence , and they perhaps are the trans action factors of GPE ⅰ .

β乳球蛋白（BLG）是反刍动物乳汁中的主要乳清蛋白，BLG表达受到βlg核心启动子、LCR、MAR等顺式作用元件和激素、转录因子等反式作用因子的调控。

Beta-lactoglobulin is a major whey protein in ruminant milk . Cis-acting elements (β lg core promoter , LCR and MAR ) and trans-acting factors ( transcription factors and hormones ) affect the expression of β lg .

通过用已知的反式作用因子与报告基因质粒分别进行共转染，提示Sp1是最为有效的反式作用因子，而不是Egr1。

Co-transfection with each of a panel of the expression plasmids of the known transcription factors with the relevant reporter construct indicates Sp1 , but not Egr-1 , is the most potent transcription factor for enhancement of the promoter activity .

反式作用因子中血清反应因子变化与心力衰竭关系的研究

Relationship between changes of serum response factor and heart failure

植物反式作用因子研究进展。

Progress in plant trans-acting factors .

真核基因的转录调控主要依赖于顺式作用元件和反式作用因子之间的相互作用。

The transcription regulation in eukaryotes depends largely on the interaction between cis-acting elements and trans-acting factors .

目的研究反式作用因子与心力衰竭相关蛋白表达量变化的关系。

Objective To investigate the relation ship between trans acting factor and the change of protein expression levels in heart failure .

研究表明，在植物维管组织特异性定位表达启动子中，顺式调控元件与反式作用因子协同作用，调控基因的表达。

The gene expression is regulated by the cooperative interaction of cis acting element and trans acting element in the plant vascular .

它涉及到染色体结构的改变、顺式作用元件和反式作用因子相互作用等多种过程。

Many events such as the alteration of chromatin structure , the interaction between cis-elements and trans-factors are involved in this process .

核受体超家族属于反式作用因子，是一类配体依赖性转录因子，其成员广泛介导了真核生物与生长、发育和内环境稳定相关基因的表达。

The nuclear receptor superfamily is composed of a large number of ligand-dependent transcriptional factors that mediate expression of genes associated with eukaryotic growth , development , and homeostasis .

对于重要的调控元件及反式作用因子给出了解释及参考文献，若要了解其详细功中文摘要能可以通过与因特网的链接功能进一步进行查询。

Explanation and references for the important regulatory elements and trans-factors are given in the database . Much more details can be enquired by linking to other databases on internet .

通过该数据库，能够查看与鼠抗体基因转录密切相关的调控元件及与之结合的反式作用因子，并能了解它们对抗体基因的转录所发挥的正向或负向调控作用。

In this database , expression regulatory elements and trans-factors of closely-related mouse antibody genes can be found and their positive or negative effects on regulation of antibody genes learned .

真核生物基因表达调控涉及顺式作用元件与反式作用因子、反式作用因子与反式作用因子之间极其复杂的相互作用。

The control of eukaryote gene transcription is a very complex procedure . It involves the interactions between cis-acting elements and trans-acting factors as well as the interactions between different trans-acting factors .

珠蛋白基因的转录受染色质结构、编码基因与其旁侧序列甲基化程度、顺式调节元件及细胞内反式作用因子的调节控制。

The transcription of globin genes is regulated by the chromatin structure , methylation of globin genes and their flanking regions , local and distal cis acting elements and cellular trans acting factors .

组织特异性启动子常常具有特异性调控元件，这些元件与反式作用因子的互作使基因只在特定的组织和器官以及特定的生长发育阶段才进行表达。

The promoter of tissue-specific expression usually have the particular regulatory elements , which make gene just carried on the expression in the particular tissue and organs and the particular growth stages by working with trans-acting factor .

花生贮藏蛋白基因只在发育的特定阶段和特定的组织器官（种子）中表达，这是多种顺式作用元件和反式作用因子协调作用的结果。

Storage protein gene of peanut express only in specific developing stage and specific tissue ( i.e. the seeds ) and this is the result of multiple kinds of cis-acting elements and trans-acting factors act in concert .