反义核酸

现在，可以下调VEGF基因表达的技术包括反义核酸技术、核酶技术以及RNA干扰技术。

The way of inhibiting VEGF gene expression includes : antisense nucleic acid technology , ribozyme technology , and RNA interference technology .

用反义核酸技术研究POLκ基因对细胞遗传稳定性的影响

Using antisense nucleic acid technology to study the influence of POL κ on genetic stability

核因子-κB反义核酸对肾病大鼠肾小球硬化细胞凋亡的干预

Intervention of antisense oligonucleotide targeting NF - к B to apoptosis in glomerulosclerosis

核因子-κB反义核酸对前炎症细胞因子表达的实验研究

Effect of NF - κ B antisense oligodeoxynucleotides on expression of proinflammatory factors

胰岛素样生长因子Ⅰ类受体反义核酸对脐血B淋巴细胞功能的调节

Effects of insulin-like growth factor type ⅰ receptor antisense nucleotide on cord blood B lymphocyte functions

目的筛选高效特异的抗HBV反义核酸药物。

Objective To explore a new specific anti HBV agent .

反义核酸抑制胃癌细胞Bcl-2表达

Expression of Bcl-2 in Gastric Cancer Cells Transducted with Antisense Bcl-2

整合素受体介导的bcl-2反义核酸对结肠癌细胞的作用

Effects of Integrin Receptor Mediated bcl-2 Antisense Oligodeoxynucleotides on Colon Carcinoma Cells

端粒酶RNA反义核酸降低鼻咽癌细胞p53蛋白表达水平

Decreased expression of p53 protein in nasopharyngeal carcinoma cells by telomerase RNA antisense oligodeoxynucleotides

反义核酸抑制人骨髓瘤细胞中的IL-6信号转导功能研究

Antagonism Function of Anti-Sense Nucleic Acids on IL-6 Signal Transduction in Myeloma Cells

反义核酸对人白血病HL60细胞中cmyc基因表达的抑制

Inhibition of human leukemia c-myc gene expression by antisense oligodeoxynucleotides

VEGF反义核酸对肿瘤放射治疗的影响及其相关基础研究和MRI监测

Effect of VEGF Anti-sense cDNA on Tumor Radiotherapy and Its Correlative Pathological Study and MR Imaging Detection

Bcl-2反义核酸增强青蒿琥酯诱导K562细胞凋亡

Bcl-2 antisense oligodeoxynucleotides to enhance the apoptosis-inducing effect of artesunate on K562 cells

Survivin反义核酸结合位点的体外筛选及鉴定

Screening and Identification of Antisense Accessible Sites of Survivin in vitro

VEGF反义核酸联合放射治疗对裸鼠移植瘤宫颈癌的作用

Effect of VEGF antisensenucleic acids united radiation therapy on nude mouse transplantation tumor uterine cervix cancer

PIP反义核酸对乙肝病毒PRE转录后调节的影响

The function of antisense PIP RNA on HBV PRE-dependent post-transcriptional regulation

Bcl-2反义核酸的设计及对K562细胞凋亡的研究

Design of Bcl-2 antisense oligodeoxynucleotide and study of its induction apoptosis in K562 cells

Bcl-2硫代反义核酸（G3139）OPC纯化方法

OPC purification of antisense phosphorothioate oligodeoxynucleotide to Bcl-2

反义核酸抑制抗敌百虫淡色库蚊扩增酯酶mRNA体外翻译的研究

Inhibition of in vitro Translation of Esterase mRNA of Dipterex-Resistant Mosquito ( Culex pipiens pallens ) by Antisense Nucleic Acids

脂质体介导ANG反义核酸对A549细胞作用的研究

Effects of ANG antisense oligonucleotide transfected by liposome on A549 cells

方法：采用TRAP法检测Hep2细胞在反义核酸处理前后端粒酶活性的变化。

Methods : Telomerase activity of Hep 2 cells with antisense treatment was measured using the TRAP assay .

bcl-2基因反义核酸对HL-60和K562白血病细胞生存的影响

Effects of Antisense Oligonucleotide of bcl-2 Gene on Survival of HL-60 and K562 Cells

3种反义核酸增加白血病细胞K562对顺铂的敏感性

Three kinds of antisense oligodeoxynucleotide enhance the sensitivity of leukemia cell K562 to cisplatin

RT-PCR产物电泳结果显示，与转染前细胞、空质粒转染细胞相比，转染survivin反义核酸的细胞SURVIVINMRNA水平明显降低。

As compared to controls , the level of survivin mRNA expression in transfected cells decreased significantly .

VEGF（121）反义核酸抑制裸鼠胰腺癌移植瘤的增殖及血管生成

Human antisense VEGF_ ( 121 ) expression vector inhibits the proliferation and angiogenesis of pancreatic cancer in nude mouse

COX-2反义核酸对喉癌恶性生物学行为的抑制作用

Inhibition of malignant phenotypes of human laryngeal cancer cells by anti-sense nucleic acid of cyclooxygenase-2

针对HBVx基因的反义核酸抑制HBV表达的体外研究

An in vitro study on inhibition of hepatitis B virus replication and expression by antisense oligodeoxynucleotides directed at HBV X translation initiator

方法：用反义核酸来封闭PML－RARα融合基因的表达并用RT－PCR的方法检测。

Methods : ASODN-mediated inactivation of the PML-RAR α mRNA was measured by RT-PCR .

端粒酶RNA反义核酸联合其催化亚单位反义核酸对子宫颈癌Hela细胞生长的抑制作用

Combination of antisense human telomerase RNA and antisense human telomerase catalytic subunit inhibits cervical cancer Hela cell growth

研究两个反义核酸（18mer，21mer）对人白血病HL&60细胞中c－myc基因表达的抑制作用。

In order to study the effect of two antisense oligodeoxynucleotides ( 18,21 mer ) on the c-myc gene expression .