手性固定相

因此，对映体手性识别机理的研究及手性固定相的制备意义重大。

So , the study of chiral recognition mechanism and the synthesis of CSPs are very important .

产物光学纯度采用手性固定相HPLC法分析。

The products were analysed by HPLC using chiral stationary phases .

HPLC手性固定相法测定乳酸光学纯度

Determination of Optical Purity of Lactic Acid by HPLC-CSP

3及其手性固定相的结构经1HNMR，IR和元素分析表征。

Their structures were characterized by 1H NMR , IR and elemental analysis .

以手性固定相（chiralstationaryphase，CSP）为基础的高效液相色谱法是目前手性拆分最主要的途径之一。

Chiral stationary phase based on high performance liquid chromatography is one of the most important ways of chiral separation .

利用PMβ环糊精手性固定相高效液相色谱法直接拆分酮咯酸氨丁三醇盐对映体。

Direct separation of ketorolac tromethamine enantiomers was studied on a PM - β - CD chiral column by high performance liquid chromatography .

手性固定相上Cr（bza）3的色谱拆分研究

Studies on the chromatographic resolution of Cr ( bza ) _3 by chiral stationary phase

光学活性配合物的合成、拆分和性能研究&Ⅲ.fac-、mer-〔Co（β-ala）3〕的手性固定相拆分和其对映体的异构化外消旋反应机理

Studies on optically active metal complexes & ⅲ . resolution of fac - and mer - [ co (β - ala ) _3 ] with chiral stationary phase and mechanism of isomerization-racemization of their enantiomers

在自制的涂敷型纤维素三（3,5二甲基苯基氨基甲酸酯）手性固定相上直接拆分了μ3S盖帽的外消旋四面体金属簇合物。

The direct chiral separation of (μ _3-S ) - bridged racemic metal clusters was performed on cellulose-tris ( 3,5-dimethylphenylcarbamate ) chiral stationary phase ( CDMPC-CSP ) .

方法：用α1-酸糖蛋白手性固定相，考察了缓冲液的种类和pH、有机改性剂的种类和比例、流速及柱温对泮托拉唑对映体拆分的影响。

Method : Influences of the pH value of the mobile phase , the organic modifiers , the flow rate and the column temperature on the enantiomeric separation of pantoprazole using α 1 - acid glycoprotein chiral stationary phase were investigated .

在所制备的手性固定相上，用配体交换色谱法研究了pH值、温度、中心离子浓度及流速对α氨基酸对映体拆分的选择性和分离度的影响，选择了合理的色谱分离条件；

On this new stationary phase , the effects of pH , temperature , concentration of Cu 2 + and flowrate on the selectivity and res ˉ olution R s of α - amino acids enantiomers have been studied under the ligand-exchange model .

为手性固定相时，利用高效液相色谱法考察了流动相组成、pH值、温度对萘普生和布洛芬对映体拆分的影响。在温度274～313K的实验范围内，R-体先被洗脱；

In the range of temperature 274 to 313 K , the R-enantiomer is eluted firstly , and the capacity factor , selectivity and resolution of enantiomers decrease as temperature increases .

利用正相高效液相色谱法在一种纤维素衍生物手性固定相（OB-H）上成功分离了一系列（7个）的R基-3-吡啶基亚砜的对映异构体。

A series of racemic R-3-pyridyl sulfoxides were successfully separated by a cellulose derivative based chiral stationary phase ( OB-H ) under normal-phase high performance liquid chromatography ( HPLC ) conditions .

制备了两种不同结构的β-环糊精型手性固定相CSPA和CSPB，制成手性色谱柱Ⅰ和Ⅱ，并且用DL-氨基酸衍生物的手性拆分实验对色谱柱进行了评价。

Two different structures of the β - cyclodextrin chiral stationary phases CSP A and CSP B are prepared . The chiral columns ⅰ and ⅱ are made . Evaluation to the columns are executed by the chiral resolution test with the derivatives of the DL-amino acid .

合成了CDMPC手性固定相并制得手性柱，对手性农药乙氧呋草黄和稻丰散对映体具有很好的识别和拆分能力。

The CDMPC CSP was synthesized and the chiral column was prepared which showed favorable enantiomeric recognition and separation potency .

电色谱柱填充强阴离子交换固定相（SAX），添加在流动相中的磺化β环糊精（SCD）动态地吸附于SAX填料表面，形成一层准手性固定相。

The capillary column was packed with strong anionic exchange stationary phase , the sulfated β - cyclodextrin ( S-CD ), which was added in the mobile phase , dynamically adsorbed to the packing surface and a new layer of chiral stationary phase was formed .

用微晶纤维素和苯甲酰氯的超声反应合成了纤维素三苯甲酯（CTB），并将其涂敷于硅胶上，用作液相色谱手性固定相。

Cellulose tribenzoate chiral stationary phase ( CTB CSP ) was prepared by a modified procedure , in which CTB was synthesized by the ultrasonic reaction of benzoyl chloride with microcrystalline cellulose and then was coated on the silica gel .

利用纤维素衍生物手性固定相（ChiralcelOJ-H手性柱），建立了氰戊菊酯4个对映异构体的正相高效液相色谱拆分方法。

A method for chiral separation of four fenvalerate enantiomers was developed by high performance liquid chromatography on the chiral stationary of cellulose derivative ( CHIRALCEL OJ-H ) .

基于氨基酸的酰胺类手性固定相的制备

The Preparation of Amide Chiral Stationary Phases Derived from Amino Acids

蛋白质及纤维素衍生物手性固定相分离盐酸昂丹司琼对映体

Enantiomers separation of ondansetron hydrochloride using proteinate-and amylase-based chiral stationary phase

高效液相手性固定相环糊精及其衍生物

High-performance Liquid Chromatography Chiral Stationary Phase - cyclodextrin and its derivatives

纤维素衍生物手性固定相的制备及其手性对映体分离

Preparation of Cellulose Derivative-based Chiral Stationary Phases for Separation of Enantiomers

聚天冬酰胺键合胰蛋白酶亲合手性固定相的初步研究&Ⅰ

Studies on the Poly-Aspartic Trypsin Chiral Stationary Phase & ⅰ

分子烙印手性固定相分离过程热力学研究

Thermodynamic Study on Separation of Molecular Imprinting Chiral Stationary Phase

偶联亲水层的牛血清白蛋白手性固定相的制备

Preparation of Bovine Serum Albumin Chiral Stationary Phase with a Hydrophilic Film

微晶纤维素类手性固定相的合成及dl-化合物的拆分

Synthesis of cellulose chiral stationary phases and resolution of dl-compound

新的环糊精手性固定相&七（2,6-二-0-正丁基-3-0-三氟乙酰基）-β-环糊精

A New Chiral Stationary Phase-Heptakis ( 2,6-di-O-n-butyl-3-O-trifluoroacetyl ) - β - cyclodextrin

复合碱性功能单体分子烙印手性固定相

Highly Efficient Molecule Imprinting Chiral Stationary Phase Utilizing Combined Basic Functional Monomers

手性固定相的结构对氨基酸对映体分离的影响

Effect of the Structures of Chiral Stationary Phases on Enantioselectivity

酰胺型手性固定相直接拆分克仑特罗对映体

Direct Resolution of Clenbuterol Enantiomers with Amide Derivative as Chiral Stationary Phase