周围神经损伤

周围神经损伤后碱性成纤维细胞生长因子mRNA表达的实验研究

Experimental Study on Dynamic Changes of Expression of Basic Fibroblast Growth Factor mRNA after Peripheral Nerve Injury

FK506加速周围神经损伤修复后的功能恢复

FK 506 accelerates functional recovery following repair of peripheral nerve injury

周围神经损伤后巨噬细胞游走抑制因子mRNA在许旺细胞的表达状况

Expression of macrophage migration inhibitory factor mRNA in Schwann cells

结论TNFα对周围神经损伤后脊神经节感觉神经元有保护作用。

Conclusions It was suggested that TNF alpha might protect sensory neurons after nerve injury .

结论：NGF对周围神经损伤有促进神经传导功能，减轻神经继发损伤的作用。

Conclusion : NGF can improve the conductive function of injured peripheral nerve .

BDNF对小鼠周围神经损伤后髓化与再生作用的实验研究

Experimental research of BDNF on myelination and regeneration of injured mice peripheral nerve

在周围神经损伤中S-100仅表达于许旺细胞中。

S-100 only appeared in Schwann cell in the peripheral nerve injury .

FK506对丙烯酰胺致大鼠周围神经损伤的保护作用

Effects of FK506 on acrylamide-induced peripheral nerve injuries of rats

周围神经损伤后大鼠背根神经节细胞NMDA受体表达的可塑性改变

Plasticity of NMDA receptor expression in rat dorsal root ganglion after peripheral nerve injury

周围神经损伤（peripheralnerveinjury，PNI）是最为常见的神经系统疾病之一，其发病率和致残率高，医疗花费巨大。

Peripheral nerve injury ( PNI ) is one of the commonest neurological disorders with high morbidity , disability and medical costs .

目的：研究神经生长液（nervegrowthdecoction，NGD）促进兔周围神经损伤的修复作用。

Objective : To explore the regenerative effect of nerve growth decoction ( NGD ) on the crushed peripheral nerve of rabbits .

微囊化转NGF基因成纤维细胞治疗周围神经损伤的研究人们对于周围神经损伤和治疗的研究多年来从未间断过，研究方法也在不断进步和深入。

Therapy of peripheral nerve injury is continuously studied and the methods are improved constantly for many years .

周围神经损伤后S-100蛋白的分布和变化研究

A study of the Distribution and Changes of S-100 Protein after Peripheral Nerve Injury

目的探讨环化酶激活剂（前列腺素E1、腺苷及Zn2+离子）对周围神经损伤后感觉神经元的保护作用。

To observe the protective effect of cyclase activator on sensory neurons after peripheral nerve injury .

目的：探讨新型的人工合成的可降解材料Poly（DL-lactide-co-ε-caprolac-tone）修复周围神经损伤的可行性。

AIM : To explore the feasibility of using the novel biomaterials , Poly ( DL lactide co ε caprolactone ), to repair the peripheral nerve defect .

周围神经损伤对脊髓运动神经元NT-3表达的影响

The change of neurotrophin 3 in spinal motor neurons following sciatic nerve lesion in rats

携GDNF基因的质粒黏附缝线促进周围神经损伤修复的实验研究

Experiment and Research on Rehabilitation of Injured Peripheral Nerves by Adhering Sutures with Plasmid of GDNF Gene

腹腔内连续应用NGF对周围神经损伤后轴浆运输恢复作用的实验研究

The Experimental Study on Axoplasmic Transportation Rehabilitation Effects by Continuous Abdominal Administration with Nerve Growth Factor ( NGF ) in Injured Peripheral Nerves

目的：观察周围神经损伤后神经细胞FOS表达及IL-6对其表达的影响。

OBJECTIVE : To observe the expression of neurocyte FOS as well as the effect of IL 6 on neurocyte FOS expression after peripheral nerve injury .

分米波在周围神经损伤后s-100蛋白表达变化中作用的实验研究

Effects of decimeter wave on the expression of immunologic reaction to s-100 protein in Schwann 's cell after peripheral nerve injury

周围神经损伤患者出入院FIM运动分、认知分、总分均无明显变化（P＞0.05），其康复效益低。

Discharge FIM motor subscale , cognitive subscale and total scores in patients with peripheral nerve injury had no change compared with their admission FIM ( P 0.05 ) .

结论周围神经损伤会引起其相应支配靶器官-肌肉组织内NGF的含量发生变化，且具有时间性，但红、白肌肉内NGF含量的变化不一致；

Conclusion The injury of peripheral nerves causes the amount of NGF in the target tissues to increase , but the change is different between the denervated muscles ;

结论：IL-6对周围神经损伤后神经细胞FOS表达有抑制作用，提示IL-6参与神经损伤后的调控过程。

CONCLUSIONS : IL 6 has an inhibitory action on neurocyte FOS expressions after peripheral nerve injury , which suggests that IL 6 participates in the control process after nerve injury .

目的探讨大鼠周围神经损伤后相应神经与脊髓组织髓鞘碱性蛋白（MyelinBasicProtein，MBP）含量变化及神经生长因子（NGF）的影响。

Objective To investigate the effect of nerve growth factor ( NGF ) on the content changes of myelin basic protein ( MBP ) in lumber spinal cord and injured sciatic nerve of Wistar rats .

本研究表明CS2引起大鼠的周围神经损伤出现轴浆运输和能量代谢功能障碍。

The research indicated that peripheral nerve damage caused by CS 2 could lead functional disturbance of axonal transport and energy metabolism .

结论周围神经损伤后，外源性IL1β对脊髓前角α运动神经元具有保护作用。

Conclusion Exogenous IL-1 β can protect α motoneurons from degeneration and necrosis after peripheral nerve injury .

3周围神经损伤后，骺板局部CGRP等神经肽分布减少，影响骺板正常发育，导致肢体短小畸形、骨质疏松。

The distribution of neuropeptides ( such as CGRP ) decrease after the brachial plexus injury , affect the development of epiphyseal plate , and cause the limb short , malformation and rarefaction .

目的研究周围神经损伤后白细胞介素-1β（interleukin-1β，IL-1β）对周围神经损伤后脊神经节神经元的保护作用。

Objective To study the effect of interleukin 1 β( IL 1 β) on neurons of spinal ganglions after peripheral nerve injury . Methods 20 wistar rats were divided into 2 groups randomly .

目的研究聚-DL-乳酸（PDLLA）可吸收医用膜防止周围神经损伤修复后粘连形成的作用。

Objective To study the effect of poly - DL - lactic acid ( PDLLA ) absorbable membrane on preventing adhesion after repair of peripheral nerve injury .

结论免疫抑制剂的使用可以延缓周围神经损伤后IL-1β、TNFα-、IFN-γ和MIF表达的峰值，而且可以明显延长其表达时间。

Conclusion Immunosuppressants can delay the expression peaks and significantly extend the expression time of IL-1 β, TNF - α, IFN - γ and MIF after repair for a sciatic nerve injury in a rat model .