瘢痕形成

关节部位瘢痕形成后的康复治疗

Rehabilitation treatment of cicatrization at joints

目的探讨外周神经损伤后，神经吻合口局部应用透明质酸（HyaluronicAcid，HA）对神经吻合口瘢痕形成的预防作用。

Objective To investigate the preventive effect of hyaluronic acid ( HA ) on scar formation following peripheral nerve injuries .

B、C组与对照组比较，均能够明显减少椎板切除术后的硬膜外瘢痕形成。

So compared to the control group , KS artificial fasciae and self-fasciae significantly reduced the formation of epidural fibrosis after laminectomy .

术前MRI表现均有脊髓软化，变形，囊肿，瘢痕形成并萎缩。

Before operation , MRI all showed that spinal intenerates , deformation , cyst , formation of scar and atrophy .

Survivin、Caspase-3在病理性瘢痕形成中的作用

Function of Apoptosis-Related Survivin , Caspase-3 in the Formation of Pathologic Scar

神经肽P物质在瘢痕形成过程中具有重要的作用，只是其与肥大细胞的关系作用机理上不太明确。

Neuropeptide substance P in scarring plays an important role in the process , but the relationship with the mast cells , the action mechanism does not clear .

He-Ne激光预处理可以减少兔眼小梁切除术后瘢痕形成。

So pretreatment rabbit eyes after trabeculectomy with He-Ne laser can reduce scarring .

结论CO2激光与冰醋酸联合治疗尖锐湿疣具有原位复发率低、创面愈合时间短及瘢痕形成率低等优点。

Conclusion Combination of CO 2 laser and acetic acid glacial is a recommended method for the treatment of condyloma acuminatum .

但现阶段国内外尚无对COX-2抑制剂与病理性瘢痕形成的相关研究。

But there is no related research on the relationship of COX-2 inhibitors and pathological scar conformation .

增生性瘢痕形成和成熟过程中c-fos、c-jun和碱性成纤维细胞生长因子基因表达的变化

Gene expression of c-fos , c-jun and bFGF in proliferative and mature hypertrophic scars

转化生长因子β、癌基因c-myc和c-fos在瘢痕形成中的作用

Effects of TGF - β _1 and oncogene c-myc and c-fos on pathogenesis of hypertrophic scar

高分子量HA外敷膜使HA渗透进入皮肤，抑制瘢痕形成。

The external using film made from high molecular weight HA could repress the formation of scar , for HA could infiltrate into dermis .

由于出血或者瘢痕形成，CNV会引起急性或亚急性的视力丧失。

CNV may cause acute or subacute blindness because of bleeding or scar formation .

组织型纤溶酶原激活剂（t-PA）对实验性青光眼滤过性手术瘢痕形成的影响

Effects of tissue plasminogen activator ( t-PA ) on scar formation after experimental filtration surgery

Ahmed房水引流物植入术后瘢痕形成的免疫组化研究

Immunohistochemical study on scarring after Ahmed aqueous drainage implantation

目的探讨丝裂霉素（MMC）预防鼻泪管探通术后瘢痕形成的有效应用浓度。

Objective To find out the effective concentrations of mitomycin C in preventing scar formation after probing of nasolacrimal duct .

目的：探讨外源性透明质酸（HyaluronicAcid，HA）在伤口愈合中可能的作用机制以及对瘢痕形成的影响。

Objective : To evaluate the effects of exogenous hyaluronic acid ( HA ) on wound healing in a model of incised wound of rat skin and their possible mechanisms .

目的：探讨S100蛋白基因的表达情况与病理性瘢痕形成的相关性。

AIM : To investigate the correlation between expression of S100 protein gene and formation of pathological scar .

目的研究抑制胶原纤维酸性蛋白（GFAP）基因表达对在体胶质瘢痕形成的影响。

Objective To investigate effect of suppression glial fibrillary acidic protein ( GFAP ) gene expression on glial cicatrix proliferation in vivo .

转化生长因子-β抑制剂Decorin抗眼结膜滤过泡瘢痕形成的实验研究

Inhibitory effect of Decorin of transforming growth factor - β on bleb scarring in rabbits

目的研究性激素对脑损伤后星形胶质细胞（Ast）反应及胶质瘢痕形成的影响。

Objective To study the effect of gonadal hormone on reaction of astrocyte and glial scar formation after brain stab injury ( BSI ) .

Lefty在创面修复和瘢痕形成过程中表达的研究

Expression of Lefty in Wound Healing and Scarring

CNV常累及黄斑，引起反复出血、渗出、瘢痕形成，严重损害中心视力。

CNV often involving the macula , has repeatedly caused bleeding , leakage , scarring , and serious damage to central vision .

TGF-β抑制剂（Decorin）抗滤过泡瘢痕形成及毒副作用的实验研究

Anti-conjunctival bleb scarring effect and toxicity of TGF - β inhibitor ( Decorin ) in rabbits after filtration surgery

结果术后随访3～6月，A组2例复发（83%），3例羊膜下有瘢痕形成；B组1例复发（42%），未见结膜植片下有瘢痕形成。

Results The patients were followed up for 6-12 months , 2 patients in A group relapsed ( 8.3 % ), 3 patients had scar formation under amniotic membrane , 1 patient in B group relapsed ( 4.2 % ), no patients had scar formation .

自组装肽包裹嗅神经鞘细胞抑制脊髓损伤后胶质瘢痕形成并促进轴突再生CNS脱髓鞘疾病生物标记物的蛋白质组学研究

Self-assembling peptide-enwrapped olfactory ensheathing cells inhibit glial scar formation and promote axon regeneration after spinal cord injury Proteome Analysis of Biomarkers in the Cerebrospinal Fluid of Central Nervous System Demyelinative Diseases

前期研究发现COX-2在血管生成、成纤维细胞迁移中起重要作用，提示病理性瘢痕形成可能与COX-2的表达有关。

Previous study found that COX-2 play an important role in angiogenesis and migration of fibroblasts cell , suggesting that the formation of pathological scar may be interrelating with the expression of COX-2 .

结论TGFβ1促进Ⅲ型胶原的合成是房水引流物植入术后瘢痕形成的原因之一。

Conclusion TGF - β 1 as one of cell growth factor inducing the synthesizing of extracellular matrix ( ECM ) such as collagen ⅲ, may play a critical role on scarring after the Ahmed aqueous drainage implantation .

组织型转谷氨酰胺酶（tTG）能催化ECM蛋白之间形成抗蛋白酶水解的交联，在ECM的沉积和瘢痕形成过程中起重要作用。

Tissue transglutaminase ( tTG ) is capable of cross - linking ECM proteins to proteolysis - resistant complexes . It has important functions in ECM accumulation and scar formation .

例4、5（扩张型心肌病。心电图示心肌坏死型）18F-FDG心肌代谢显像示浅淡缺损区，除极小部分放射充填外均未见放射性充填（非存活心肌-坏死或瘢痕形成）。

Case 4 and 5 suffering from dilated cardiomyopathy and myocardial necrosis in ECG showed non-alive myocardium-necrosis in most myocardial areas demonstrated by 18F-FDG myocardial metabolic imaging .