路易体痴呆

目的探讨路易体痴呆（dementiawithLewybody，DLB）的早期诊断。

Objective To investigate the early characteristic diagnosis of dementia with Lewy body ( DLB ) .

目的对轻、中度阿尔茨海默病和路易体痴呆患者进行临床表现和1H-MRS研究，以期对疾病的早期诊断、鉴别诊断和治疗有所帮助。

Objective To analyze the clinical manifestations and () ~ 1H-magnetic resonace spectroscopy ( ~ 1H-MRS ) examinations of Alzheimer 's disease and dementia with Lewy Body , and further provide evidence for early diagnosis , differential diagnosis and treatment .

路易体痴呆的临床和～1H-MRS分析

The Clinical Feature and ~ 1H-MRS Analysis of Dementia with Lewy Bodies

方法对6例路易体痴呆患者的临床症状、体征、神经心理检查和辅助检查进行分析，对其中5例进行~1H-MRS检查，观察NAA、Cho、Cr各代谢产物浓度的改变。

Method : We analyzed the clinical feature , sign , neuropsychological examination and auxiliary examination of 6 cases of dementia with Lewy bodies . 1H - MRS examination was performed in 5 of these cases . Concentrations of NAA , Cho and Cr were evaluated .

路易体痴呆误诊1例报道

Misdiagnosis of dementia with Lewy bodies : report of one case

路易体痴呆八例临床分析

Clinical analysis of 8 dementia with Lewy bodies

以波动性认知功能障碍、视幻觉和帕金森病综合征为路易体痴呆的特征性临床特点。

Fluctuating cognitive impairment , visual hallucination , and Parkinsonism are all its clinical characteristics .

路易体痴呆的诊断

The diagnosis of dementia with Lewy body

阿尔茨海默病和路易体痴呆的临床和~1H-MRS分析

Clinical and ~ 1H-magnetic Resonace Spectroscopy Analysis on Alzheimer 's Disease and Dementia with Lewy Body

认识路易体痴呆

Understanding dementia with lewy bodies

方法对8例临床诊断的路易体痴呆患者的资料进行回顾性分析。

Methods A clinical , neuropsychological , neuroimaging and therapeutic analysis on 8 cases of clinically diagnosed dementia with Lewy bodies was conducted .

方法：复习文献，分析路易体痴呆患者的病理改变和临床表现特点，了解其治疗和预后。

METHODS : Pathological changes and clinical manifestation of dementia with Lewy body were analyzed as well as its treatment and prognosis through the review of literatures .

结论认知功能减退的患者出现波动性认知功能障碍、反复的视幻觉和帕金森样运动障碍应高度怀疑路易体痴呆。

Conclusion : Fluctuating cognitive impairment patient with recurrent visual hallucinations and spontaneous motor features of Parkinsonism shall be high suspected to be dementia with Lewy bodies .

目的分析路易体痴呆的临床表现和~1H-MRS的改变，以期有助于早期诊断、鉴别诊断和有效治疗。

Objective : To evaluate the clinical feature and 1H-MRS alteration of dementia with Lewy bodies for the purpose of early diagnosis , differential diagnosis and effective therapy .

结论患者海马NAA/Cr值降低能为阿尔茨海默病和路易体痴呆的早期诊断提供有价值的信息，有效指导临床治疗。

Conclusions The decrease of hippocampus NAA / Cr ratios of patients with Alzheimer 's disease and dementia with Lewy body might be helpful for their early diagnosis and effective treatment .

目的：路易体痴呆的发病率是仅次于阿尔茨海默病的第2位痴呆症，约占痴呆患者的15%～25%。

AIM : Dementia with Lewy body has ranked the second in the incidence of dementia , only inferior to Alzheimer disease , accounting for 15 % to 25 % of all dementia patients .

结论：对路易体痴呆和进行性核上性麻痹及时做出诊断，并与其他相关疾病做鉴别是非常重要的，可以为治疗的选择及护理提供有益的信息。

CONCLUSION : Early diagnosis and differentiation of dementia with Lewy bodies or progressive supranuclear palsy from other relevant diseases is important , which can provide useful information for the determination of treatment and caregivers .

阿尔茨海默病组较对照组有明显的双侧海马NAA/Cr值降低，路易体痴呆组较对照组左侧海马NAA/Cr值降低差异均有统计学意义。

Compared with the control group , NAA / Cr ratios of bilateral hippocampus in Alzheimer 's disease group significantly devreased ( P < 0.05 ), as well as those of left hippocampus in dementia group .