胆固醇酯

载脂蛋白E及胆固醇酯转运蛋白基因多态性与冠心病的相关研究

Interaction between ApoE and cholesteryl ester transfer protein polymorphism and effects on coronary heart disease

mmLDL与MCSF对动脉壁细胞胆固醇酯蓄积的协同作用

Synergism of mm-LDL and M-CSF on the Accumulation of Cholesteryl Ester in Aortic Cells

~（14）C标记合成脂蛋白样颗粒法测定血清中胆固醇酯转运蛋白活性

Determination of cholesteryl easter transfer protein activity in serun by ( 14 ) ~ C labeled cholesteryl ester DBP

在细胞内载脂蛋白与胆固醇酯（CE）组分经历一个解离过程。

Apoproteins and CE components dissociate from endocytic lipoprotein in the cells .

以PCRRFLP检测胆固醇酯转运蛋白（CETP）基因TagⅠB多态性。

Cholesterol ester transfer protein ( CETP ) gene polymorphism was assayed by PCR-RFLP .

氧化修饰LDL对培养人脐静脉内皮细胞DNA合成和胆固醇酯合成的影响

Effects of Oxidized LDL on DNA Synthesis and Cholesterol Ester Synthesis in Cultured Human Umbilical Vein Endothelial Cells

中性胆固醇酯水解酶活性在COS细胞中高度表达

High Expression of Neutral Cholesteryl Ester Hydrolase Activity in COS Cell

胆固醇酯转运蛋白D~（442）→G突变对高密度脂蛋白胆固醇水平的影响

Effect of the Mutation D ~ ( 442 )→ G in Cholesteryl Ester Transfer Protein Gene on the Level of Serum High Density Lipoprotein Cholesterol

SPM促进细胞内胆固醇酯向游离胆固醇转化。

SPM could induce cholesterol ester to convert into free cholesterol in the cells .

结论胆固醇酯转运蛋白第15外显子D442→G突变与高密度脂蛋白胆固醇水平升高密切相关。

Conclusion Exon 15 D ~ ( 442 )→ G mutation in cholesteryl ester transfer protein is related to the elevated level of serum high density lipoprotein cholesterol .

结论：CHF可导致血清胆固醇酯脂肪酸组成发生变化。

Conclusion Changes in fatty acid composition of serum cholesteryl esters exist in the patients with CHF .

胆固醇酯转移蛋白TaqIB基因多态性与辛伐他汀调脂疗效的相关性

Association of cholesteryl ester transfer protein-Taq IB polymorphism with therapeutic effects of simvastatin

分子流行病学研究已经表明胆固醇酯转运蛋白（Cholesterylestertransferprotein，CETP）基因是冠心病（CoronaryHeartDisease，CHD）的易感基因之一。

Molecular epidemiological studies have demonstrated that cholesteryl ester transfer protein ( CETP ) gene is one of the susceptibility genes for coronary heart disease ( CHD ) .

胆固醇酯转运蛋白基因373Ala→Pro和451Arg→Gln的突变频率及其对脂质代谢的影响

Allele Frequencies of Mutations 373 Ala → Pro and 451 Arg → Gln in Cholesterol Ester Transfer Protein Gene and Their Influences on Lipid Metabolism

目的：研究正常妊娠者血清胆固醇酯转运蛋白（CETP）水平特征。

Objective : To investigate the serum concentration of CETP in healthy pregnancy female .

目的阐述胆固醇酯转运蛋白（CETP）抑制剂的研究新进展。

Objective To review the recent progress in the inhibitors of the cholesteryl ester transfer protein ( CETP ) .

目的：了解胆固醇酯转运蛋白（CETP）对动脉粥样硬化的致病关联性。

Objective : To study the relation between serum cholesteryl ester transfer protein ( CETP ) concentration and atherosclerosis ( AS ) pathogenesis .

方法：采取空腹静脉血测定CHF患者血清TG，TC，HDL和LDL水平，采用高效液相色谱法测定血清胆固醇酯脂肪酸的组成，并与健康对照组进行比较。

Methods The levels of serum TG , TC , HDL , and LDL in 36 patients with CHF and 20 healthy controls were measured and fatty acid cholesteryl esters were determined by high performance liquid chromatography .

目的证实胆固醇酯转移蛋白（CETP）基因15外显子错义突变（442D∶G）是导致高α脂蛋白血症的重要因素之一。

Objective To validate that the exon 15 missense mutation ( 442D ∶ G ) of CETP gene plays an important role in the induction of hyperalphalipoproteinemia .

目的探讨胆固醇酯转移蛋白（CETP）基因Taq1B位点多态性是否会影响高脂人群血清高密度脂蛋白胆固醇（HDL-C）对膳食因素的反应。

Objective To analyze the effects of cholesterol ester transfer protein ( CETP ) Taq 1B polymorphism on the response of serum HDL-C to dietary factors in hyperlipidemia patients .

目的研究胆固醇酯转移蛋白（CETP）TaqⅠB基因多态性对血脂水平的影响。

Objective To study the Taq ⅰ B RFLP in the first intron of the cholesteryl ester transfer protein ( CETP ) gene , blood lipid profile and CETP mass in order to determine their association .

目的探讨肾移植患者胆固醇酯转运蛋白（CETP）基因多态性与脂代谢的关系。方法生物化学方法检测肾移植患者移植前及移植后6～8个月时的血脂水平；

Objective To investigate the effect of the gene polymorphism of cholesterol ester transfer protein ( CETP ) on the serum lipid levels in renal transplant patients .

胆固醇酯转运蛋白（CETP）是杀菌蛋白基因家族的重要成员，其主要功能是介导血浆中的胆固醇酯逆向从外周组织转运至肝脏中。

Cholesteryl ester transfer protein CETP is a key member of bactericidal gene family and plays an important role in reverse transportation of cholesterol from the peripheral tissues to the liver .

结果显示，72h后，反义寡核苷酸处理组细胞内胆固醇酯显著下降到（199±19）mg/g，油红O染色显示，该组细胞质内红色脂滴明显减少。

The results shown , the antisense oligonucleotides treated cells contained significantly lower cholesteryl ester ( 19.9 ± 1.9 ) mg / g for 72 h. It was also shown by Oil Red O staining that the experimental group cells had less lipid droplets .

目的：检测中国人群动脉粥样硬化（AS）患者和正常人的胆固醇酯转运蛋白（CETP）基因15外显子D442G突变和14内含子I14A突变。

Objectives : To examine the frequency of exon 15 missense mutation ( D442G ) and intron 14 splice defect ( I14A ) in cholesteryl ester transfer protein gene in Chinese atherosclerotic subjects .

胆固醇酯转运蛋白基因多态性与他汀类药物的调脂效应

The polymorphisms of CETP gene and lipid regulating effects of statins

桥链冠醚卟啉及卟啉胆固醇酯的表观质子化常数

Overall Protonation Constants of Bridged Crowned Porphyrins and Porphyrin-cholesterol Ester

胆固醇酯转运蛋白基因突变患者低密度脂蛋白亚组分颗粒直径增大

Low Density Lipoprotein Particle Size in Patients with CETP Gene Mutation Increases

卟啉化合物的研究ⅩⅩⅢ.卟啉胆固醇酯的合成及性质研究

Study on porphyrin compounds ⅹⅹⅲ . synthesis and photosensitivity of porphyrin-cholesterol ester

胆固醇酯转移蛋白抑制剂的研究进展

Progress in the study of the inhibitors of cholesteryl ester transfer protein