组织因子

结论心房颤动患者血浆组织因子途径改变表现为凝血活性增高和抗凝活性减低，组织因子凝血途径参与了心房颤动患者心房血栓形成机制。

Conclusions The changes of tissue factor coagulation pathway were involving in the mechanisms of atrial thrombosis in patients with atrial fibrillation .

方法：FⅦa测定采用重组可溶性组织因子法；

Method : F ⅶ was detected with recombinant soluble tissue factor method .

氧化型低密度脂蛋白抑制人内皮细胞组织因子通路抑制子mRNA的表达

Oxidized Low Density Lipoprotein Inhibited Tissue Factor Pathway Inhibitor mRNA Expression in Human Endothelial Cells

IL-6下调血管内皮细胞组织因子抑制物表达

IL-6 inhibits tissue factor pathway inhibitor expression in human umbilical vein endothelial cells

核转录因子NFκB对APL细胞组织因子的调节及三七总甙影响的实验研究

Transcription Factor κ B Regulated Tissue Factor in APL Cells and Effects of PNS

目的检测正常足月妊娠羊水中是否存在组织因子（TissueFactor，TF）这一凝血反应启动因子。

Objective To determine whether tissue factor ( TF ) is present in the amniotic fluid of normal term pregnancy .

组织因子（TF）与胃癌发生发展的关系

Role of Tissue Factor in Gastric Cancer and the Underlying Mechanism

结论AMI发作期间体内组织因子途径被启动，血液呈现高凝状态。

Conclusion During the onset of AMI , TFP is initiated and the blood is in hypercoagulable state .

植物雌激素α-玉米赤霉醇降低组织因子及核转录因子AP-1和NF-κB水平的作用

Phytoestrogen α - Zearalanol Markedly Reduces Tissue Factor Levels and Down-regulates Transcription Factors AP-1 and NF - κ B

不同PPAR配体对LPS诱导的人单核细胞组织因子表达的影响

The effect of PPAR ligands on the LPS-induced tissue factor expression in human monocytic cells

目的检测正常足月妊娠胎盘、蜕膜和子宫肌层中是否富含在启动凝血、止血过程中起关键作用的组织因子（TissueFactor，TF），初步探讨TF与产科凝血间的关系。

Objective To explore the relationship between obstetrical coagulation and tissue factor ( TF ), the key component of the initiation of coagulation .

目的探讨组织因子（TissueFactor，TF）、血管内皮生长因子（VascularEndothelialGrowthFactor，VEGF）在乳腺癌的表达与肿瘤临床和病理的关系。

Objective To study the relationship between expression of tissue factor ( TF ) and vascular endothelial growth factor ( VEGF ) and clinical pathology in breast cancer .

结果发现：外源性的组织因子途径抑制物（TFPI）可使PT及APTT延长。

The results showed that PT and APTT were prolonged by exogenous TFPI .

组织因子（TF）基因等异常表达直接影响内皮细胞抗血栓特性。

The abnormal expression of TF gene may directly affect the anti-thrombotic properties of endothelial cells .

目的研究组织因子（TF）表达对阿霉素诱导人神经母细胞瘤细胞凋亡的影响。

Objective To investigate the regulation of tissue factor ( TF ) on chemotherapeutic reagent induced apoptosis in human neuroblastoma .

肾上腺髓质素对oxLDL诱导的HUVECs组织因子及其抑制物表达的干预作用

Effect of adrenomedullin on tissue factors and TFPI expression in HUVECs treated with oxLDL

结论：川芎嗪可以抑制内皮细胞表达组织因子和释放vWF。

Conclusion : TMP can inhibit the expression of TF and the release of vWF induced by thrombin in BAECs .

目的：研究组织因子途径抑制物（tissuefactorpathwayinhibitor，TFPI）这一新型抗凝蛋白在脑出血与脑梗塞中的表达，探索其临床意义。

Objective : Evaluation of clinical significance in determination of tissue factor pathway inhibitor ( TFPI ) ma new type anticoagulation protein levels in plasma with the patients of cerebral hemorrhage and cerebral infarction .

智力结构中动物下蛋（AE）和木块图案（BD）分测量表分及知觉组织因子显著低于对照组；

The animal egg and block design subtest scores and perceptual organization factor scores in FAD group showed significantly lower than those of the control group .

近年研究发现，组织因子（TF）是凝血瀑布的主要启动因素，在动脉血栓形成中起关键作用。

Recent studies have showed tissue factor ( TF ) plays a major role in arterial thrombosis . TF is the main initiator of the coagulation cascade .

目的建立检测组织因子（TissueFactor，TF）mRNA荧光定量的方法，了解组织中TF的表达水平，研究TfmRNA的表达与肿瘤的关系。

Purpose To establish a FQ ? PCR ( fluorogenic quantitative RT ? PCR ) method for detecting the expression of tissue factor gene in tissue and investigate the relationship between TF mRNA expression and tumor .

大量实验与临床资料表明组织因子途径抑制物（tissuefactorpathwayinhibitor，TFPI）和组织因子（TissueFactor，TF）失去正常平衡状态，这与血栓性疾病的发生发展密切相关。

A number of experimental and clinical studies have shown that the imbalance of tissue factor ( TF ) and tissue factor pathway inhibitor ( TFPI ) is closely related with the cause and the development of thrombosis diseases .

目的：观察组织因子途径抑制物（TFPI）启动子部位-287T→C点突变不同型的血浆水平及与不稳定心绞痛（UAP）的关系。

Objective : To discuss the relationship between plasma level of plasma tissue factor pathway inhibitor ( TFPI ) that of promoter - 287 T → C polymorphism and unstable angina pectoris ( UAP ) .

目的探讨核转录因子NF-κB在肿瘤坏死因子α（TNF-α）、血管紧张素Ⅱ（AngⅡ）诱导血管内皮细胞组织因子（TF）表达中的作用。

Objective To study the effect of nuclear transcription factor NF - κ B on tumor necrosis factor α( TNF - α) or angiotensin ⅱ( Ang ⅱ) - induced tissue factor ( TF ) expression in human vascular endothelial cells .

补阳还五汤对凝血酶诱导血管内皮细胞释放NO，vWF，TFPI及表达组织因子的影响

Effects of Buyang huanwu decoction on the release of vWF , NO and TFPI and the expression of tissue factor induced by thrombin in cultured bovine aortic endothelial cells

目的：血小板粘附、激活、聚集和组织因子（TF）激活凝血系统、活化凝血酶是伴随斑块破裂冠脉内急性血栓形成进而引发急性冠脉综合征（ACS）的基本机制。

Objective : Upon plaque rupture , platelet adhesion , activation and aggregation , and coagulation activation by tissue factor , leading to intracoronary thrombosis , are fundamental mechanisms of acute coronary syndromes ( ACS ) .

目的探讨高盐饮食对自发性高血压卒中倾向鼠（SHRSP）血浆组织因子途径抑制物（TFPI）活性的影响。

Objective To investigate whether tissue factor pathway inhibitor ( TFPI ) activity is influenced by high sodium loading in spontaneously hypertension stroke-prone ( SHRSP ) rats .

目的探讨角膜基质细胞组织因子途径抑制物2（TFPI-2）的表达情况，为角膜新生血管的基因治疗提供方法。

Objective To observe the expression of TFPI-2 in corneal keratocytes in vitro and investigate the experimental basis for curing corneal neovascularization with gene-therapy .

结论颈动脉狭窄时，切应力能够诱导动脉狭窄处内皮细胞组织因子基因表达，其表达与内皮细胞转录因子Egr-1和Sp1介导有关。

Conclusion In carotid artery stenosis , the shear stress can up-regulate TF expression in the endothelium , and its mechanism is related to the activation of Sp1 and Egr-1 .

结果提示，切应力是内皮细胞组织因子基因表达上调的触发因素之一，其触发机制与转录因子Egr1和Sp1介导有关。

Conclusion The shear is one of a starting regulator of TF expression in endothelium . Their effect is mediated by transcription factors nuclear factor Egr-1 and Sp1 .