组织芯片

组织芯片制备与原位分析技术

Preparation of tissue array and applications of in situ analysis technology

目的采用组织芯片和图像分析技术阐述染矽尘大鼠早期肺组织炎性损伤过程中肿瘤坏死因子-α（TNFα）表达的变化规律。

Objective To evaluate the temporal expressions of tumor necrosis factor - α( TNF - α) in early stage of silica exposed rat lungs by tissue array and image process technology .

利用组织芯片技术检测硒蛋白P在胃癌组织中的表达

Expression of selenoprotein P in multiple carcinoma tissues with tissue microarray

组织芯片应用于原发性鼻咽癌中p53表达的高通量分析

Application of high-throughput tissue microarray technique on p53 protein expression in nasopharyngeal carcinoma

HIF-1αmRNA在肺癌组织芯片中的表达意义

The Role of Expression of HIF-1 α mRNA in Lung Carcinoma on Tissue Microarray

目的定量检测人脑星形细胞肿瘤组织芯片中血管内皮生长因子（VascularEndothelialGrowthFactor，VEGF）的表达及微血管结构参数及其意义。

Objective To observe the expression of vascular endothelial growth factor ( VEGF ) and the parameters of the microvascular architecture in human astrocytomas .

chan皮肤鳞癌组织芯片中P53与VEGF表达的关系

The relationship of the expression of p53 and VEGF in skin squamous cell carcinoma tissue microarray

组织芯片研究肿瘤转移相关基因mRNA及蛋白在胃癌中的表达意义

Study on the Expression and Significance of mRNA and Protein of Tumor Metastasis Related Genes in Human Gastric Carcinoma by Tissue Microarray

肺癌及癌前病变组织芯片中PTEN的表达及其意义

Expression of PTEN and its role in lung cancerous and pre cancerous lesions

应用自制组织芯片研究抑癌基因PTEN在口腔鳞癌中的表达

Expression of Tumor Suppressor Gene PTEN in Oral Squamous Cell Cancer Using Tissue Microarray Techniques

组织芯片技术研究胆囊癌MMP-2和TIMP-2的表达及意义

Expression and significance Of MMP-2 and TIMP-2 in human gallbladder carcinoma by tissue microarray

Livin、Caspase-3及Bcl-2在大肠腺癌组织芯片中的表达及临床意义

Expression and Clinical Significance of Livin 、 Caspase-3 and Bcl-2 in Colorectal Adenocarcinoma with Tissue Microarray

利用组织芯片技术分析肝细胞癌组织P21~（WAF1/CIP1）、PCNA和Ki-67的表达及意义

Expression of P21 ~ ( WAF1 / CIP1 ), PCNA , Ki-67 in HCC by tissue chip assay

应用组织芯片、免疫组化检测200例肝癌组织中OPN表达。

Immunohistochemistry of OPN was performed in the tissue arrays containing 200 HCC samples .

标本制成组织芯片，采用免疫组化SABC法对芯片标本进行染色。

The tissue chips were analyzed by the SABC immunohistochemical method .

VEGF、Cath-D在喉复发癌组织芯片中的表达和意义

Significance of VEGF and Cath-D expressions in tissue arrays of patients with recurrent laryngeal carcinoma

组织芯片技术研究VEGF-C、MMP-2与胰腺癌血管、淋巴结转移的关系

To Investigate the Expression of VEGF-C and MMP-2 in Pancreatic Cancer and Its Relations to Micrometastasis by Tissue Microarray

Caveolin-1及其相关蛋白在肺癌组织芯片中的表达和生物学意义

Expression of Caveolin-1 and Related Protein and Their Biological Significance in Lung Cancer Tissue Microarray

组织芯片技术是病理学研究中的高效、快速工具。p53表达与胃癌预后无显著相关性，UICC分期仍然是胃癌的独立预后指标。

P53 expression is unrelated to prognosis in gastric carcinoma . UICC staging retained significant independently in prospecting prognosis .

应用组织芯片技术观察HPV16/18相关外阴尖锐湿疣DNA倍体类型及cyClinD1、P53、P21~（WAF1）蛋白的表达

Expression of DNA ploidy and cyclin D1 , P53 , P21 ~ ( WAF1 ) protein in HPV16 / 18 positive vulva condyloma acuminatum by tissue microarray

应用组织芯片技术检测Elf-1及Survivin在非小细胞肺癌中表达的临床意义

Clinical significance of detecting expression of Elf-1 and Survivin in non-small-cell lung cancer with tissue chip

消化道肿瘤组织芯片中BAG-1的表达及意义分析

Expression and Significance of Apoptosis Related Gene BAG-1 in Digestive Tract Cancer by Tissue Microarray

原发性皮肤大B细胞淋巴瘤患者中与疾病特异性存活时间相关的bcl-6和MUM1/IRF4蛋白的表达：组织芯片研究

Expression of the bcl - 6 and MUM1 / IRF4 proteins correlate with overall and disease-specific survival in patients with primary cutaneous large B-cell lymphoma : A tissue microarray study

冰冻组织芯片OCT模块和HE切片的观察：模块上的组织芯排列基本整齐，组织芯无缺损，芯与芯之间无挤压扭曲现象；

Result : 1 . OCT block of frozen tissue microarray and HE-stained : The cores on frozen tissue microarray were regularly arranged and had no shift and distort .

方法采用组织芯片平台，应用免疫组织化学方法结合计算机图像分析技术检测160例浸润性乳腺癌组织MMP-2、MMP-9、TIMP-1和TIMP-2蛋白表达及其相应比值大小。

Methods The expression of proteins MMP-2 , MMP-9 , TIMP-1 , and TIMP-2 was examined by immunohistochemistry S-P in 160 cases of infiltrating carcinoma tissues on tissue chip platform .

我们前期通过对组织芯片和不同转移潜能的肝癌细胞进行检测，发现在低分化的肝组织及高转移潜能的肝癌细胞中ezrin的表达增高。

It came that over expression of ezrin was found in low differential tumor tissues and HCC cell lines with high metastasis potential .

背景和目的：探讨（1）组织芯片运用的可行性；（2）Fas、FasL与结肠癌的免疫逃避的关系。

Background & Objective : ① To detect the feasibility of the application of TMAs and ② to investigate the role of Fas / Fas ligand ( FasL ) in tumor immune in colon adenocarcinoma .

方法应用7种不同类型的一抗，2张不同肿瘤的组织芯片，同时进行EnVision法、LsAB法、标准CSA法和改进CSA法染色，比较敏感性和特异性。

Methods : Using 7 different types of primary antibodies and 2 tumor microarray system , we carried out EnVision , LSAB , Standard CSA , and modified CSA staining and compared their sensitivities and specificities .

采用组织芯片技术和免疫组织化学方法检测不同卵巢组织中SPARC的表达，同时对蛋白表达进行定位。

The differential protein expression of SPARC in normal ovarian tissues and ovarian epithelial carcinoma was analyzed by tissue microarray technology and immunohistochemistry analysis and located using well characterized monoclonal antibodies .

结果组织芯片上细胞形态和BAG-1蛋白表达情况与相应的常规切片上的情况表现出高度一致性（K>0.75）。

Results The morphous of cells and the expression of BAG-1 in tissue microarray was very accordant to that in normal tissue slice ( K > 0.75 ) .