基序

调节破骨细胞分化的RANK特异性基序的再确认

Re-identification of special motif regulating osteoclast differentiation in RANK

B型流感病毒核酸疫苗和CpG基序免疫增强作用研究

Influenza B Virus DNA Vaccine and Adjuvant Effect of CpG Motif

HBV转录后调节基序相互作用蛋白的筛选与鉴定研究

Screening and Identification of the Interacting Proteins of HBV Post-Transcriptional Regulatory Element

人乳头瘤病毒11型DNA中CpG基序甲基化状态分析及生物活性的研究

Methylation and biological activity of CpG motifs in human papillomavirus 11 DNA

经DNA测序和氨基酸序列分析，证实目标片段编码的肽段含有烃羟化酶的特征基序.由此确认采用该方法分离到了长链烷烃降解基因的alkB同源体片段。

From DNA sequencing and analysis of peptide sequence , signature motifs of alkane hydroxylase were found in target product of PCR .

利用噬菌体肽库技术获得与人Fas结合的多肽基序

Use a phage display library to identify oligopeptides binding to the Fas

含CpG基序的寡脱氧核苷酸联合乙型肝炎表面抗原免疫转基因小鼠的实验研究

CpG oligodeoxyribonucleotide with HBsAg for vaccination in HBsAg - transgenic mice

CpG基序的作用机理及其在寄生虫学上的应用

Mechanism of action and application in Parasitology of CpG motif

应用含CpG基序的寡脱氧核苷酸增强HBsAg诱导健康小鼠抗-HBs产生的实验研究

Enhancing effect of oligodeoxyribonucleotide containing CpG on humoral immune response induced by HBsAg in healthy mice

cpGODN是指含有胞嘧啶磷酸鸟嘌呤基序（CPGDNA）的寡脱氧核苷酸。

The CpG ODN denotes the oligodeoxyribonucleotide which contains the cytosine-phosphoric acid-guanine motif ( CpG DNA ) .

引入CpG基序的汉滩病毒G2糖蛋白基因的克隆及表达

Clone and Expression of Glycoprotein Gene G2 Added with Hantaan Virus ' CpG Motifs

利用锌指基序的保守性从人脑组织分离新的C2H2型锌指蛋白基因表达序列

Isolation of novel expression sequences of c_2h_2 type zinc finger protein gene from human brain tissue according to the conservation of zinc finger motif

含CCT基序的寡核苷酸对TLR7/9介导的天然免疫应答的抑制作用

Inhibitory Effect of Oligonucleotides Containing CCT on TLR7 / 9 Mediated Innate Immune Response

含CpG基序寡核苷酸对慢性乙型肝炎患者外周血树突状细胞的免疫激活研究

Immunostimulatory role of CpG-containing oligodeoxynucleotide on the monocyte-derived dendritic cell in patients with chronic hepatitis B

Fbox蛋白是一类含有Fbox基序（motif），在泛素介导的蛋白质水解过程中具有底物识别特性的蛋白质家族。

F box protein is an expanding family of eukaryotic protein characterized by an F box motif which has specificity of substrate recognition in the ubiquitin mediated proteolysis .

目的探讨合成含CpG基序的寡核苷酸（cpGODN）在肿瘤免疫治疗中的研究。

Objective To study the immunotherapy role of CpG ODN ( CpG oligodeoxynucleotide ) on tumor .

CpG基序甲基化状态及其调控因素在SLE发病机制中的作用研究

Study of the Role of Methylation of CpG Motifs and Its Regulation Factors in the Pathogenesis of Systemic Lupus Erythematosus

LEA蛋白质11-氨基酸基序与植物抗旱性

11-amino acid motif in late embryogenesis abundant protein ( LEA ) and plant desiccation tolerance

方法利用分子力学随机构象搜索法和混合MonteCarlo方法，对Titin蛋白PEVK片段中的PVAP基序进行构象搜索。

Methods The conformational analysis was carried out by random search and hybrid Monte Carlo method .

这两个序列中含有多个复制转录因子的结合位点、增强子基序、多个完全的和非完全的反向重复序列以及潜在的DNA弯曲核心序列样结构。

Both the MAR loci show numerous replication / transcription factor binding sites , enhancer motifs , several perfect or imperfect inverted repeats , and sequences sharing the common features of the potential DNA bending core sequence .

结论：CpG基序是人食管癌疫苗的有效佐剂，HLA对T细胞功能有影响。

Conclusion : CpG may be the optimal adjuvant of human esophageal tumor vaccine and the HLA gene locus may affect T cells function .

汉滩病毒G1蛋白胞质区ITAM样基序功能的研究

Identification of Conserved and Functional ITAM-like Sequences within G1 Cytoplasmic Tail of Hantaan Virus

大量研究表明，含未甲基化CpG基序的细菌基因组DNA和人工合成的cpGODN是人和多种动物有效的免疫激活剂。

Many studies indicate that unmethylated CpG motifs of bacterial genomic DNA and synthetic CpG ODN were a powerful activator of human and animal immune .

进一步通过荧光光谱法证实，含多拷贝11-氨基酸基序的多肽可通过多位点协同结合模式，稳定LDH酶的结构。

Furthermore , the fluorescence spectroscopic results show that the peptide consisting of multi-copies of11-amino acid can stabilize the structure of LDH through synergy and multi-sites binding .

血管抑制素功能结构域K1与PKA底物磷酸化基序的融合表达及磷酸化标记

Fusion Expression of Functional Domain K1 of Angiostatin with PKA Phosphorylating Motif and Labeling of the Protein by Phosphorylation

SRY基因是一种转录因子，属于带有高迁移率族蛋白家族，该家族成员包含能与DNA结合的HMG盒基序。

SRY represents a transcription factor belonging to the superfamily of genes sharing the HMG-box motif ( high-mobility group-box ), which acts as DNA binding region .

采用PCR－SSCP检测及DNA测序技术，对一例46，XY女性患者SRY基因的HMG基序进行了突变分析。

The HMG region in SRY gene of a patient with 46 , XY karyotype and gonadal dysgenesis was analyzed using the PCR-SSCP and DNA sequencing techniques .

一种含多拷贝CpG基序的质粒构建及其对水产动物的免疫调节作用

Construction of a Recombinant Plasmid Containing Multi-copy CpG Motifs and Its Immuno-modulating Effects on the Immune Responses of Aquatic Animals , Fish and Prawn

其中，两个MAR序列中包含有TG、CA和GA阻断以及ATTA基序。

Sequences of the two chosen MAR loci are composed of TG - , CA - and GA - blocks , as well as the ATTA motifs .

结合前面的序列比对得出结论，DAG基序突变为DTG能使病毒的蚜传活性大大降低，甚至丧失。

The mutation from DAG to DTG resulted in low transmission efficiency , even loss of the transmission ability by aphid .