基因修复机制
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- genetic repair mechanism
基因修复机制
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这种肿瘤显示为微卫星不稳定性,一种获得性基因特征暗示DNA修复机制缺陷。
Such tumors display microsatellite instability , an acquired genetic characteristic that indicates defects in DNA-repair machinery .
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单链寡核苷酸介导基因定点修复的作用机制研究
Mechamism Studies of Targeted Gene Repair Mediated by Single-Stranded Oligonucleotides
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他们把每种肿瘤的众多基因突变案例进行比较,区分出对某种肿瘤来说,哪些突变是共同的(从而,估计是致病原因),哪些突变是偶然的(恶性细胞中的基因修复机制经常出错,所以偶然突变是常见的事)。
They are comparing the mutations in many examples of each type , to find which are common to a type ( and thus , presumably , causative ) and which are mere accidents . ( The DNA-repair apparatus in malignant cells often goes wrong , so such accidents are common . )