外源性化合物

这些酶的重要作用之一就是清除脂溶性外源性化合物，包括环境中的毒物和药物。

An important role of these enzymes is to aid in the elimination of lipophilic xenobiotics , including environmental toxins and drugs .

细胞色素P450（CytochromeP-450，CYP450）是动物体内主要的代谢酶系，在外源性化合物的生物转化中起着重要的作用。

Cytochrome P450 ( CYP450 ) is the major metabolic enzymes of animals in vivo , which plays an important role in the biotransformation of endogenous compounds .

细胞色素P450（CYP450）是由大量同工酶组成的一组超基因家族，对大多数内源性化合物和外源性化合物的代谢起着重要的作用，该酶系在药理学中具有极其重要的研究意义。

Cytochrome P450 ( CYP450 ) enzymes represent a superfamily of monooxygenases that play a pivotal role in metabolism of endogenous and exogenous compounds , which have great research significance in pharmacology .

人类细胞色素P450s（CYP450s）对许多内源、外源性化合物在体内的I相生物转化有重要作用。

Cytochrome P450s ( CYP450s ) involved in the phase I metabolism of a variety of chemically diverse substances ranging from endogenous compounds to xenobiotics .

血清白蛋白是血浆中含量最丰富的蛋白质，它可以贮存和转运许多物质，包括内源性化合物和外源性化合物。

Serum albumin , the most abundant protein in blood plasma , can storage and transport many substances , including endogenous substances and exogenous substances .

背景与目的外源性化合物代谢酶参与环境致癌物在体内的代谢，代谢酶基因多态性被认为与肺癌的易感性相关。

Background and objective Genetic polymorphism in metabolic enzymes , which are involved in metabolism of environmental carcinogens , have been thought to be related to susceptibility of lung cancer .

近年来，有关外源性化合物对动物和人内分泌系统的干扰进行了广泛的研究。

In recent years , much attention has been focused on the potential for a wide range of xenobiotic chemicals to interact with and disrupt the endocrine systems of animal and human populations .

病原是外源性阿片类化合物，靶部位是阿片受体。

The target is opioid receptors .