选择性转录

乳腺癌和良性病变中很多外显子被差异性表达，以及促成乳腺癌分子特征的选择性转录子。

Many exons are differently expressed by breast cancer and benign lesions , and alternative transcripts contribute to the molecular characteristics of breast malignancy .

以上免疫共沉淀实验、ChIP检测和基因研究结果表明，hnRNPA2/B1可以选择性结合反转录转座子并且募集具有沉默转座子功能的HP1。

Our results from co-immunoprecipitation experiments , ChIP assays and genetic studies suggest that hnRNP A2 / B1 could bind to selective retrotransposons and recruit HP1 for transposon silencing .

目前，对于Alu序列的功能了解得还不透彻，据推测主要与基因调控有关，如基因重排、CpG甲基化、hnRNA选择性剪切、结合转录因子和激素等。

Now the functions of Alu elements are still unclear . It is speculated that Alu elements are involved in aspects of gene regulation , e.g. gene rearrangement , CpG methylation , alternative splicing of hnRNA , binding sites of transcription factors and hormone receptors , etc.