纤连蛋白

N－糖链在纤连蛋白分泌及纤连蛋白受体与配体结合中的作用

The Role of N-Linked Oligosaccharides in the Secretion of Fibronectin and the Binding of Fibronectin Receptor with Ligand

ELISA法检测培养液中纤连蛋白（FN）的含量；

ELISA method was used to detect the level of secreted fibronectin ( FN ) .

人胎盘纤连蛋白N糖链结构研究

Study on the Analyses of N-linked Oligosaccharide of Fibronectin Purified from Human Placenta

转移性腺样囊性癌细胞纤连蛋白和硫酸乙酰肝素蛋白多糖mRNA的表达

Expression of HSPG and Fibronectin mRNA in Metastatic ACC Cell Line

各组系膜细胞增殖及分泌纤连蛋白和纤连蛋白mRNA表达情况。

Proliferation and secretion and mRNA gene expression of fibronectin in every group .

II型纤连蛋白重复序列（FNII）；

A fibronectin type II repeat region ;

结论：成功地表达了纤连蛋白各片段，蛋白芯片杂交结果显示纤连蛋白可能是通过Ⅱ型肝素结合区及其羰基端（c端）与HBsAg相互作用。

Conclusion : Fibronectin may interact with HBsAg by its heparin-binding domain and carboxyl terminus ( c terminus ) .

上皮性卵巢癌中纤连蛋白、层粘蛋白和IV型胶原蛋白表达呈一致性（P<0.05）。

Expressions of FN , LN and col IV of ovarian epithelial carcinoma were correlated .

去势SD大鼠股骨骨髓细胞纤连蛋白（FN）的表达

Expression of FN in Bone Marrow Cells of Femur of Ovariectomy SD Rats

并用免疫组化法观察了IV胶原、纤连蛋白（FN）。

Immunohistochemistry was used to examine the expression of fibronectin ( FN ) and collagen ⅳ .

NaCl溶液中纤连蛋白在TiO2表面吸附的动力学模拟

Adsorption of fibronectin on TiO_2 ( 110 ) surface in NaCl solution by molecular dynamic simulation

方法通过脑室注射Aβ1-40，建立大鼠AD模型，采用逆转录PCR方法研究纤连蛋白在皮质、海马的表达情况。

Methods The model of Alzheimer 's disease of rat was established by injection of A β 1 40 to cerebral ventricle . RT ?

采用ELISA法检测细胞培养上清液中细胞外基质成分纤连蛋白（FN）以及促纤维化细胞因子转化生长因子β1（TGFβ1）的分泌水平。

The secretion level of fibronectin ( FN ) and TGF - β 1 in HK-2 cells were assayed by ELISA .

以纤连蛋白（FN）细胞结合片段研究大鼠肝星状细胞FN受体表达及调控

Study of modulation of fibronectin receptor expression in rat hepatic stellate cells with fibronectin cell-binding fragment

特别是纤连蛋白（FN）及整合素β1（integrinβ1）表达明显上调。

Fibronectin ( FN ) and integrin beta 1 ( fibronectin receptor ) were dramatically over-expressed in the top of all up-regulated genes .

急性时相蛋白：抗凝血酶Ⅲ、血浆纤连蛋白、前白蛋白和白蛋白在文昌鱼中的组织定位以及LPS处理后浓度的变化

Acute Phase Proteins : Antithrombin ⅲ, Plasma Fibronectin , Transthyretin and Albumin , Their Locations in Amphioxus and the Changes of Their Concentrations after Treatment with LPS

IgA肾病患者血清IgA1诱导正常人肾小球系膜细胞钙离子释放、转化生长因子β表达上调和纤连蛋白分泌

IgA_1 from patients with IgA nephropathy induced release of calcium , up-regulation of TGF - β mRNA expression and secretion of fibronectin in human glomerular mesangial cells

结果经MPTP腹腔注射后褐鼠模型出现典型PD症状，黑质酪氨酸羟化酶表达水平明显降低，黑质纤连蛋白基因表达明显上调。

Results The PD models were verified successfully by typical symptoms and obvious reduction of tyrosine hydroxylase expression in substantia nigra after peritoneal administration of MPTP .

序列分析表明，片段与GenBank中登录的金黄葡萄球菌纤连蛋白结合蛋白A序列的同源性为99.1%。

Sequence analysis demonstrated that its homology with the fibronectin - binding protein A of Staphylococcus aureus on GenBank was 99.1 % .

p38信号通路对腹膜间皮细胞p27~（kip1）和纤连蛋白的影响

High glucose induces p27 ~ ( kip1 ) expression and fibronectin secretion in human peritoneal mesothelial cells via p38 MAPK activation

目的研究整合素αvβ3、黏着斑激酶（FAK）、纤连蛋白（FN）和基质金属蛋白酶-9（MMP-9）在结直肠癌转移中的作用机制。

Objective To study the roles of integrin α v β 3 , focal adhesin kinase , fibronectin , matrix metalloproteinase 9 in the metastasis of colorectal cancer .

目的探讨细胞外基质纤连蛋白（Fn）、基膜连接蛋白（Lm）与白血病细胞生长、分化之间的关系。

Objective To investigate the relationship between quantitative change of fibronectin ( Fn ) or Laminin ( Lm ) and growth and differentiation of leukemic cells .

目的：探讨上皮性卵巢肿瘤细胞外基质重要成分纤连蛋白、层粘蛋白和IV型胶原蛋白成分表达及改变的意义。

Objective : To explore the expression and significance of extracellular matrix in epithelial ovarian tumor by examination of fibronectin ( FN ), laminin ( LN ) and collagen IV ( col IV ) .

猪链球菌PCR检测方法的建立及纤连蛋白结合蛋白的克隆和表达1（PAI！1）、纤维蛋白原（Fg）。

Development of Multiplex PCR for Diagnosing the Disease Caused by Streptococcus Suis and Cloning and Expression the Fibrinogen-binding Protein of Streptococcus Suis Type 2 Fibrinogen ( Fg ) were measured .

纤连蛋白对人舌癌细胞系TCa8113细胞体内浸袭行为的影响

Effect of Fibronectin on the Invasion Behaviour of Human Tongue Cancer Cell Line ( TCa8113 ) in vitro

探讨整合蛋白α5β1和纤连蛋白（FN）表达与肝细胞癌（HCC）生物学行为间的关系。

PURPOSE To study the relationship between the expression of integrin α 5 β 1 , and fibronectin ( FN ) and the biologic behavior of human hepatocellular carcinoma ( HCC ) .

目的观察N-糖链抑制剂衣霉素（TM）对肾小球系膜细胞（GMC）增殖、凋亡及纤连蛋白（FN）的影响。

Objective To investigate the effects of tunicamycin ( TM ) - inhibitor of N-glycosylation of proteins on proliferation and apoptosis of glomerular mesangial cells ( GMC ) and synthesis of FN .

结论：降低GPIPLD活性能增加骨髓单个核细胞对纤连蛋白的黏附率，与此同时，骨髓单个核细胞上GPI锚定蛋白CD24的表达增强。

It is concluded that depression of GPI-PLD activity can increase the adhesion rate of bone marrow mononuclear cells from the patients while the CD24 expression is enhanced .

体外实验发现CB可以降解纤连蛋白、Ⅰ型胶原蛋白、Ⅳ型胶原蛋白和层粘连蛋白等细胞外基质成分，还可以激活尿激酶型纤溶蛋白酶原激活剂、基质金属蛋白酶等。

In vitro , cathepsin B can hydrolyze extracellular matrix such as fibronectin , I type collagen , IV collagen and laminin proteins , but also is able to activate urokinase-type plasminogen activator 、 matrix metalloproteinases .

并用免疫组化观察了胶原Ⅳ、纤连蛋白（FN）、增殖细胞核抗原（PCNA）和巨噬细胞趋化蛋白1（MCP-1）。

Renal pathological changes were evaluated and immunohistochemistry was used to examine the expression of fibronectin ( FN ), collagen ⅳ, macrophage chemoattractant protein 1 ( MCP-1 ) and proliferating cell nuclear antigen ( PCNA ) .