非翻译区
- non-translated region;non-translational region
![非翻译区](../cache/1172876.jpg)
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用PCR方法扩增了麦洼牦牛α-乳清蛋白基因5′-非翻译区的部分序列。
Partial sequence in 5-flanking non-translated region of yak α - lactalbumin gene is amplified and shares 98.1 % homology with that of bovine .
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牦牛α-乳清蛋白基因5′-非翻译区部分序列测定及PCR-RFLP分析
Sequencing and PCR-RFLP analysis of the partial 5 ′ flanking non-translated region of yak α - lactalbumin gene
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用IREFINDER算法在非翻译区搜索人和小鼠的铁反应元件
IRE_FINDER & Computational Search of Iron Response Element in Human and Mouse UTRs
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用DNA直接测序法对患者FⅦ基因的全部外显子和其侧翼以及3′,5′非翻译区进行分析,寻找基因突变,对有突变的序列反向测序证实;
F ⅶ gene mutations were analysed in the proband by DNA direct sequencing of PCR products of all exons , exon-intron boundaries and the 3 ′, 5 ′ untranslated sequences .
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中国南方人群Fc受体γ链基因3′端非翻译区基因多态性与系统性红斑狼疮的关系
Polymorphism in 3 ' untranslated region of Fc receptor γ chain gene in patients with systemic lupus erythematosus in southern China
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PI3KγmRNA3′非翻译区可能存在基因表达负调控区
Probable Existence of a Negative Regulation Region Within the 3 ′ UTR of Human Phosphoinositide 3-Kinase γ mRNA
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结果TGFβ3基因测序总长度5457bp,共发现7个SNP,位于内含子区5个、编码区和3′非翻译区各1个。
Results Seven SNPs in the exons , introns and 3 ′ untranslated region ( 3 ′ UTR ) of TGF β 3 gene were identified .
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方法用DNA直接测序法对先证者FⅦ及组织因子(TF)基因的全部外显子及其侧翼5′和3′非翻译区进行分析,寻找突变基因。
Methods All exons , exon-intron boundaries and the 3 ′, 5 ′ untranslated sequences of F ⅶ and tissue factor ( TF ) genes were amplified by PCR and sequenced directly .
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结论IDC患者CTLA-4基因转录和表达缺陷,该缺陷与CTLA-4基因3′末端非翻译区(AT)n重复序列多态性存在关联。
Conclusion Defective translation and expression of CTLA-4 take place in patients with IDC , it is possibly related to the CTLA-4 gene microsatellite polymorphism .
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5′端非翻译区对LT-B基因表达的影响
Effect of 5'non-coding Region on Expression of LT-B Gene
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目的:利用已有质粒构建带GFP报告基因的启动子鉴定质粒,并用此质粒鉴定丙型肝炎病毒5非翻译区(HCV5'-UTR)启动基因表达的活性。
Objective ; To construct a promoter identifying plasmid with GFP as reporter gene , and then identify the promoter activity of HCV 5 ' - UTR with this construct .
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近来大家较为关注一种调节mRNA稳定性,由富含AU元件(AREs)介导的特殊途径,这一般发生于生存期短的mRNAs的3端非翻译区。
There has been growing interest in a particular pathway which regulates mRNA stability , and is mediated by AU-rich elements ( AREs ), usually found in the 3 ` untranslated region ( UTR ) of short-lived mRNAs .
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ERIC(IRU)局限于基因组可转录区,即多顺反子操纵子基因间区域,或开放阅读框架上、下游非翻译区。
ERIC ( IRU ) is restricted to transcribed regions of the genome , either in intergenic regions of polycistronic operons or in untranslated regions upstream or downstream of open reading frames ( ORF ) .
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以上生物学特性的研究以及对其CP基因和3′-非翻译区序列的分析证明此病毒为紫藤脉花叶病毒(WVMV),这是关于此病毒在中国发生的首次报道。
The above biological properties and sequence analysis of the coat protein gene and 3 ' non-translated region ( NTR ) showed that this potyvirus is Wisteria vein mosaic virus ( WVMV ) .
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本研究旨在探讨CTLA-4基因启动子-318C/T、外显子A/G多态性及3′非翻译区(AT)n微卫星多态性与IDC及血清可溶性CT-LA-4(sCTLA-4)水平的相关性。
This study was conducted to investigate the association of CTLA-4 gene promoter - 318C / T polymorphism , exon 1 A / G polymorphism and 3 ′ untranslated region microsatellite polymorphism with susceptibility to IDC in Han Chinese .
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目的:探讨变性高效液相色谱(DHPLC)在胰岛素受体底物2(IRS2)基因3′非翻译区单核苷酸多态性(SNP)检测中的应用。
Objective To explore the use of denaturing high-performance liquid chromatography ( DHPLC ) in detecting single-nucleotide polymorphisms ( SNPs ) of insulin receptor substrate-2 ( IRS-2 ) gene 3 ′ - untranslated region ( 3 ′ - UTR ) .
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该基因在3′-端非翻译区(3′-UTR)具有硒代半胱氨酸插入序列(SECIS)结构,其大小为102bp。
The gene contained a selenocysteine insertion sequences ( SECIS ) element in its 3 ′ - untranslated region ( 3 ' - UTR ) at the size of 102 bp .
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水稻蜡质基因5'非翻译区一个与调控有关的内含子
A Regulation-related Intron in 5 ' Untranslated Region of Rice Waxy Gene
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哺乳动物基因非翻译区开放阅读框架的分析
Open Reading Frames Analysis on Untranslated Regions of Mammal Genes
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基于支持向量机的人类5'非翻译区剪接位点识别
Identification of 5'UTRs splice sites in human gene based on support vector machine
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内含子和5'非翻译区对人血小板生成素基因表达的影响
Role of intron and 5 ' untranslated region in human thrombopoietin gene expression
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3′端非翻译区对重组人肝细胞生成素表达不均一性的影响
Affects of the 3 ′ untranslated region on expression of recombinant human hepatopoietin
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人转化生长因子β1基因非翻译区的改造及其全长序列测定
Modification and complete sequence analysis of human transforming growth factor - β _1 cDNA
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利用多样性增量位置得分函数预测人类5'非翻译区剪接位点
Prediction of splice sites in human 5'UTRs by use of position score funtion based on increment of diversity
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真核基因非翻译区剪接位点识别算法的研究。
The research on method for splice sites identification in eukaryotic gene untranslated coding regions ( UTR ) .
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该克隆还包括了5'端和3'端非翻译区,分别为72个和438个碱基对长。
The 5 ' and 3 ' untranslated regions of the message were 70 and 446 bases long , respectively .
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与一般剪接位点不同,5'非翻译区剪接位点的两侧不存在由编码到非编码的状态转移,所以通常的剪接位点识别算法在非翻译区的性能不太理想。
Different from the conventional splice sites identification , there is no transition from coding to non-coding in 5'UTRs , so conventional splice sites prediction methods perform poorly in UTRs .
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和编码区一样,真核基因的非翻译区在转录后期也进行了剪接,但是在翻译时并不被翻译成蛋白质。
The seem to the coding regions , the UTR of eukaryotic gene are also been spliced during gene transcription . However , these exons are not translated into protein during gene translation .
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非翻译区剪接位点的两侧不存在编码到非编码的状态转移,因为它的内含子和外显子均是非编码的,所以对非翻译区中的剪接位点进行识别较难。
Since the state transition from coding to non-coding is absent , the exons and the introns of untranslated regions are all non-coding sequences . The identification of splice sites embedded in UTR is more challenge .
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研究可变剪接调节的关键问题是:如何在海量的基因组序列中识别出剪接位点?围绕这一问题,本文对真核基因编码区与非翻译区分别建立了剪接位点识别模型。
The key questions in alternative splicing regulation are : How are splice sites recognized in the vast genomic sequence ? This thesis built splice sites identification models for coding regions and untranslated regions in eukaryotic gene , focusing on this question .