非竞争性抑制剂

动力学研究（Lineweaver-Burk作图法）发现，GLPIA1是蛋白酶A的非竞争性抑制剂。

Kinetic studies ( Lineweaver-Burk method ) showed GLPIA_1 is a kind of noncompetitive inhibitor to yeast proteinase A .

染料木素是表皮生长因子受体酪氨酸激酶结构域（EGFR-TK）高度特异的非竞争性抑制剂。

Genistein is a high specific and noncompetitive inhibitor of epidermal growth factor receptor tyramine kinase domain ( EGFR-TK ) .

结论龙葵碱是NAT酶2-AF底物的非竞争性抑制剂。

CONCLUSION Solanine is a non-competitive inhibitor of NATs .

一个非竞争性抑制剂的净结果相当于转化某些酶成为钝化形式。

The net result of a non-competitive inhibitor is equivalent to converting some of the enzyme present to an inactive form .

非竞争性抑制剂箭毒，在酶的外周阴离子部位有表现不同亲和力的两种结合作用，只有其中高亲和力的抑制作用为钙离子解除。

There were two kinds of association of different affinities between the peripheral anionic sites of the enzyme and the non-competitive inhibitor curare . Only the inhibition with the higher affinity was eliminated by calcium ions .

由甲基化引起基因沉默而出现的肿瘤，可通过DNA甲基转移酶非竞争性或竞争性抑制剂抑制甲基化的发生，活化沉默的抑癌基因，从而达到治疗肿瘤的目的。

Caused by the methylation of gene silencing the tumor , available through DNA methyltransferase non-competitive or competitive inhibitors methylation occurs , activating the silence of the tumor suppressor gene , so as to achieve the aim of the treatment of tumors .

目的探讨新型非竞争性5α还原酶抑制剂爱普列特（epristeride）治疗良性前列腺增生（BPH）的有效性及安全性。

Objective Study the efficacy and safety of epristeride , a new uncompetitive 5 α - reductase inhibitor , in the treatment of benign prostatic hyperplasia ( BPH ) .