青蒿素

提取青蒿素实验条件的研究

Study experiment condition of extracting arteannuin from artemisia annua

青蒿素是中国科学家自主创新的倍半萜内酯类抗疟化合物。

The arteannuin is an antimalarial drug that was developed independently by scientists of China .

诺贝尔奖得主屠呦呦周一宣布，她的团队提出青蒿素抗药性问题的解决方法，证明青蒿素仍是治疗疟疾的“最好武器”。

Nobel Laureate Tu Youyou announced Monday that her team has proposed solutions to the problem of artemisinin resistance , giving new proofs that artemisinin is still " the best weapon " against malaria .

在来自60个研究机构的500多名科学家的努力下，终于在上世纪70年代发现了青蒿素，青蒿素联合疗法是当前最有效的抗疟药物。

This effort , involving more than 500 scientists from 60 institutions , led to the discovery in the 1970s of artemisinin – the core compound of artemisinin-based combination therapies ( ACTs ) , the most effective antimalarial drugs available today .

青蒿素抗柯萨奇B组病毒感染的实验观察

Study on anti - Coxsackie virus B 3 effect of artemisinin

用流式细胞术分析双氢青蒿素对杜氏利什曼原虫DNA的作用

Effect of Dihydroartemisinin on Leishmania donovani Promastigotes DNA analysed by flow cytometry

吡啰红B为指示剂细胞色素C催化荧光测定青蒿素

Fluorescence Determination of Artemisinin Using Cytochrome C as Catalyst and Pyronine B as Indicator

HPLC同时测定复方双氢青蒿素片中磷酸哌喹与甲氧苄啶的含量

Determination of piperaquine phosphate and trimethoprim in Compound Dihydroartemisinin tablets by HPLC

青蒿素类药物的HPLC法测定研究

Studies on the assay of semi-synthetic derivatives by HPLC

此类药物是被称为ACTs的以青蒿素为基础的联合治疗的关键成分。

These medicines are the key ingredient of artemisinin-based combination therapy , or ACTs .

30℃下硅胶对青蒿素的饱和吸附量为35.2mg／g。

The adsorption capacity of artemisinin on silica gel was 35.2 mg / g at 30 ℃ .

HPLC和双波长分光光度法测定复方双氢青蒿素片中甲氧苄啶含量的比较

Comparison of Trimethoprim Content in Compound Dihydroartemisinin Tablets Determined by Dual-wavelength Spectrophotometry and HPLC

HPLC法测定青蒿素胶囊中青蒿素的含量

Determination of artemisinin in artemisinin capsules by HPLC

结论双氢青蒿素可杀死Pc滋养体和包囊，从而减轻肺组织的炎症反应。

DHA may kill Pc trophozoites and cysts and alleviate inflammatory responses in the lung tissues in PCP rats .

双氢青蒿素对Lewis肺癌小鼠的抑瘤作用

Anti-tumor Effect of Dihydroarteannuin on Lewis Lung Cancer Bearing Mice

青蒿素诱导人白血病细胞K562凋亡的线粒体机制

Mitochondrial Mechanisms of Apoptosis Induced by Artemisinin in Human Leukemia K562 Cells

基因芯片技术分析二氢青蒿素抑制K562细胞增殖的作用机制

Analyzing the anti-K562 cell mechanisms of dihydroartemisinin with gene chip

青蒿素的Raman光谱研究

Raman Spectroscopy Study of Artemisinin

青蒿琥酯为青蒿提取物青蒿素的衍生物，它不仅保留了青蒿的功效，且现代研究显示其具有免疫抑制和免疫调节作用，故可以用来治疗SLE。

Artesunate has a immune double adjusting effect and can treat SLE .

二氢青蒿素对人乳腺癌MCF-7细胞的体外抑制作用

Effect of dihydroartemisinin on the proliferation of MCF - 7 cell

青蒿素对体外培养的HeLa细胞生长的影响

Effect of artemisinin on the growth of HeLa cells

该地区的许多人正在仅仅使用青蒿素，而不是推荐的青蒿素联合疗法（ACTs）。

Many people in the area have been using artemisinin alone , rather than in artemisinin combination therapies ( ACTs ) as recommended .

相对标准偏差小于1.1%，分析的加样回收率为98.9%。测定了青蒿素在超临界CO2中的溶解度。建立了一套流动法测定固体溶质在超临界CO2中溶解度的实验装置。

The recovery is 98.9 % . A flow-type apparatus has been built for solubility determination of solid in supercritical CO2 .

比较高效液相色谱法（HPLC）和双波长分光光度法对复方双氢青蒿素片中甲氧苄啶含量测定的作用。

Objective To compare the effects of dual-wavelength spectrophotometry and HPLC on the content of trimethoprim ( TMP ) in Compound Dihydroartemisinin Tablets .

抗疟新药青蒿素（Artemisinin）的某些含氮衍生物在动物实验中还显示局部麻醉效应。

Some derivatives of artemisinin have been shown to have local anesthesia action .

目的：观察二氢青蒿素（DHA）对大鼠系膜细胞（MC）增生的抑制作用。

Objective : To investigate the inhibiting effect of dihydroartemisinin on proliferation of rat mesangial cells in vitro .

双氢青蒿素对人喉癌细胞HeP-2生长抑制作用的实验观察

Inhibitory effect of pair of hydrogen artemisinin on HeP-2 cells of throat cancer

目的研究双氢青蒿素（DHA）治疗对大鼠体内卡氏肺孢子虫（Pc）超微结构的影响。

Objective To study the effects of dihydroartemisinin ( DHA ) on the ultrastructural changes of Pneumocystis carinii ( Pc ) in rats .

它可以作为“单一药物疗法”单独使用，也可以在更昂贵的“青蒿素联合疗法”（artemisinincombinationtherapy，act）中，与其它药物同时使用。

That drug is artemisinin , available either by itself as a " monotherapy " , or with other drugs as a more costly artemisinin combination therapy , or act .

通过光谱滴定法可计算二者的结合比和结合常数，同样获得1个DNA结合4个青蒿素分子，结合常数为4.0×104，与电化学方法测定结果相吻合。

The experiments of spectroscopic titration indicated that one DNA molecule combined with four artemisinin molecules and the binding constant reached 4.0 × 104 , which was similar to the result from electrochemical method .