难治性休克

继发性MODS多存在慢性疾病状态和恶性病，以全身炎症反应综合征（SIRS）、脓毒血症（sepsis）、难治性休克为主要表现。

Severe dehydration or sudden cardiopulmonary arrest , while the risk factors for the secondary MODS listed below was severe chronic disease and malignancies with systemic inflammatory response syndrome ( SIRS ), sepsis and refractory shock as the main presentation .

临床上以全身多部位反复出血、难治性休克、多脏器功能不全为主要表现。

The primary clinical features were repetitive and multiple hemorrhage in the whole body , refractory shock or multiple organ malfunction .

目的旨在探讨特利加压素（Terlipressin）对脓毒血症难治性休克的临床应用价值。

Objective To evaluate the clinical efficacy of Terlipressin for treatment of intractable septic shock .

在失血性休克首次打击的基础上，用内毒素作为第二次打击复制大鼠难治性休克模型，6h后处死动物，用放射免疫分析法测定血清TNF-α和IL-6的含量。

The rat models were made by hemorrhagic shock as the first hit and with endotoxin as the second hit . Then the rats were killed after 6 h. The contents of serum TNF - α and IL-6 in rats were measured by radioimmunoassay .

结论对严重脓毒血症难治性休克，特利加压素具有一定的临床应用价值。

Conclusion Terlipressin have clinical therapeutic effects for intractable septic shock .

流行性出血热难治性休克23例临床分析

Clinical analysis of 23 cases of stubborn shock complicated by epidermic hemorrhagic fever