错配修复基因
- 网络mmr;Mismatch repair gene;mismatch repairing genes
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DNA错配修复基因甲基化在肝细胞癌发生发展中的作用
Methylation of mismatch repair gene ( MMR ) in primary hepatocellular carcinoma
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DNA错配修复基因产物表达与肿瘤恶性程度相关性的初步探讨
The preliminary research of significance of DNA mismatch repair gene product expressions in tumor cells
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DNA错配修复基因hMSH2蛋白表达与胃癌发生关系的探讨
Study of relationship between expression of DNA mismatch repair gene hMSH_2 and generation of gastric cancer
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对结肠癌DNA错配修复基因突变携带者的识别及存活率的评估
Identification and survival of carriers of mutations in DNA mismatch - repair genes in colon cancer
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青年人结直肠癌DNA错配修复基因表达和DNA倍性检测
The expression of DNA mismatch repair genes and detection of DNA ploidy in young patients with colorectal carcinoma
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5-氮-2′-脱氧胞苷对人卵巢癌细胞凋亡及DNA错配修复基因表达的影响
Effects of 5-aza-2 ' - deoxycytidine on apoptosis of ovarian cancer cells and on expression of mismatch repair genes
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子宫颈癌错配修复基因产物与p53表达
Mismatch Repair Gene Protein Product and the p53 Expression in Cervical Squamous Cancer
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目的建立一种以多重PCR-高效液相色谱(Highperformanceliquidchromatography,HPLC)分析为基础的错配修复基因DNA大片段缺失检测技术。
Objective Establishing a new method on the basis of multiplex PCR-high performance liquid chromatography ( HPLC ) for screening a large deletion in mismatch repair genes .
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幽门螺杆菌对AGS细胞DNA错配修复基因表达的影响
Effects of Helicobacter pylori on expression of DNA mismatch repair genes in AGS cell line
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DNA错配修复基因mutS的高效表达及表达产物活性鉴定
High Expression and Identification of DNA Mismatch Repair Gene mutS in Escherichia coli
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DNA错配修复基因MutS的克隆和表达
Cloning and expression of mismatch repair gene MutS
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用RTPCR方法监测5种人类错配修复基因在膀胱癌细胞系mRNA转录水平的表达;
The expression of mRNA by RT PCR of 5 human mismatch repair ( MMR ) genes in bladder tumor cell line was evaluated .
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PCR-SSCP银染法在检测错配修复基因突变中的应用
The application of detecting mismatching repair gene mutation by the method of PCR-SSCP
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DNA错配修复基因缺陷的MSI-H大肠癌频发Ki-ras基因点突变
Frequent Ki-ras Mutation in MSI-H Colorectal Cancer Deficient in DNA Mismatch Repair Genes
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人类错配修复基因在HNPCC家系中的突变研究
Mutation of human mismatch repair genes in hereditary nonpolyposis colorectal cancer ( HNPCC ) families
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子宫颈鳞癌HPV16感染对错配修复基因表达的影响
Effect of human papillomavirus 16 infection on expression of mismatch repair gene in cervical squamous cancer
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DNA错配修复基因SNPs是个体间DNA错配修复能力差异的主要原因,是决定机体肿瘤易感的一个重要因素。
SNPs of DNA mismatch repair ( MMR ) genes is the main cause in individual difference of ability about DNA mismatch repairing , which is an important factor in deciding tumor susceptibility of the body .
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近年来普遍认为DNA甲基化与肿瘤抑制基因包括错配修复基因、血管生成抑制基因、细胞粘附分子相关基因的失活有关,是肿瘤发生的第三种机制。
DNA hypermethylation is associated with transcriptional inactivation of including mismatch repair gene , vascular regulatory gene , defined tumor suppressor genes , adhesion molecule gene in human cancer and is established as the third mechanism by which tumor suppressor genes are inactivated .
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这些基因包括癌基因、抑癌基因和DNA碱基错配修复基因等,对细胞的增殖和分化等生物学过程具有重要的调控作用。
It is reported that colorectal carcinoma is involved in a procedure of multi-gene changes . These genes include oncogenes , tumor suppressor genes , and DNA mismatch repair genes , and so on . They play an important role in cell proliferation and differentiation .
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在这一描述中,错配修复基因突变是HNPCC的始因,多种肿瘤发病风险增高是HNPCC的主要表现。
In this description , mutation of mismatch repair genes is the driving factor of HNPCC and the main manifestation of HNPCC is increased risk of cancer .
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并非所有临床诊断的HNPCC均携带有错配修复基因突变,并非所有突变携带者都会发生肿瘤。
For instance , it is not that all clinically diagnosed HNPCC carry mutant mismatch repair genes , it is not that all the mutant gene carriers grow cancer .
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人错配修复基因2、细胞增殖核抗原在宫颈癌组织中的表达及意义
HMSH_2 and Ki-67 Antigen Expression in Cervical Cancer and Its Significance
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错配修复基因与大肠癌相关性的研究进展
Progression in the relationship between mismatch repair gene and colorectal carcinoma
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慢性粒细胞白血病错配修复基因的研究
Study on mismatch repair genes of chronic myeloid leukemia
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人类错配修复基因及其与急性白血病发病机制的关系
Human mismatch repair gene and the relation between it and pathogenesis of acute leukemia
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错配修复基因相连锁的微卫星与慢性粒细胞白血病急性变的关系
The genetic instability of mismatch repair gene linked microsatellite and the evolution of CML
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乳腺癌和癌前病变微卫星不稳定性及错配修复基因表达的研究
Microsatellite Instability and Mismatch Repair Genes Expression in Sporadic Breast Cancer and Precancerous Lesion
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定量多重PCR-高效液相色谱分析错配修复基因大片段缺失
Large deletion in mismatch repair genes uncovered by quantitative multiplex PCR-high performance liquid chromatography system
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错配修复基因与金属致癌
Mismatch Repair Gene and Metal Carcinogenesis
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脆性组氨酸三聚体基因及错配修复基因hMLH1在口腔鳞状细胞癌中的表达及意义
Expression of fragile histidine triad gene and mismatch repair gene hMLH_1 in oral squamous cell carcinoma