起始密码子

此外有35条序列在CDS字段标注的翻译起始位点前存在起始密码子ATG，我们分析可能是RefSeq数据库中对其标注有误，其正确性有待进一步考证和研究。

In addition , another initiator codon ATG was found preceding the translation initiation site marked in ' CDS ' in 35 mRNAs . We doubted the marker and it needs further investigation .

根据α-珠蛋白基因起始密码子上游及终止密码子下游的保守序列设计引物，以牦牛基因组DNA为模板克隆并测定了α-珠蛋白基因序列。

The α - globin gene of yak was amplified and cloned by using the primers based on the conserved region of the upstream from the initiation codon and the downstream from the termination codon .

分A、B两种亚型，它们分别是由一条单基因通过两个不同的起始密码子转录而成，在乳腺的发生发展以及乳腺癌的增生过程中发挥了重要作用。

It has two isomers , hPR-A , hPR-B , which are transcribed from two AUG in a single gene , play the important roles in the development of mammary glands and the proliferation of breast cancer .

目标起始密码子多态性（SCoT）：一种基于翻译起始位点的目的基因标记新技术

SCoT : A Novel Gene Targeted Marker Technique Based on the Translation Start Codon

起始密码子为ATG，终止密码子为TAA。

The start codon of the COX ⅰ is ATG , while the termination codon TAA .

分析结果在表明原核与真核分析对象的平均码距在起始密码子附近和终止密码子附近均呈现出显著变化，在原核生物的SD区域也有显著变化。

We observe that average code distances fluctuate obviously near the initiation codon and termination codon . Remarkable changes also appear in the SD field of procaryotic organisms . 2 .

提出了一个识别基因起始密码子的第一ATG规则。

The first ATG rule for recognizing the start codon of gene coding sequences is given .

rPA小基因起始密码子位于β-酪蛋白信号肽编码区下游。

The initiation codon of rPA minigene is located in the downstream area of signal peptide coding region .

COI基因的起始密码子多变，大都为假定起始密码子，其中以密码子CGA的使用最多。

All kinds of start codons of CO I gene are mostly presumptive , the most of which is CGA .

通过计算，我们认为绝大多数的生物之所以选择ATG作为起始密码子，可能是因为有利于蝙蝠波的连贯性。

Calculation results suggested that most organisms select ATG as the start codon probably for the sake of Bat wave consistency .

具有HLAA2的感染者W，Z部分氨基酸序列中该表位的起始密码子发生无义突变，测序资料中包含稳定的变异位点的肽段，符合MHC结合肽的基序（motif）。

In the HLA A2 positive individuals , some of the sequences showed amber mutation on the initial codon of the epitope . Peptides with persistent amino acid transitions contained MHC binding peptide motif .

其次是3′端9bp的局部密码子偏性，SD序列与起始密码子ATG之间碱基数在8±3范围内与表达水平无显著关系。

There was no statistical significance between expression levels and the number of bases from SD sequence to initial codon ATG which was in the scope of 8 ± 3bp .

为了获得高效的生长回补效率，通过改变asdB基因的SD序列以及起始密码子优化了这一系列表达系统。

To obtain a highly efficient growth rate , the SD sequence and start codon of asdB gene were changed to construct various expression systems .

与AUG在阅读框1出现明显的缺失相反，三联体UAA在起始密码子附近的频率有了显著的增加。

Contrary to AUG depletion , the frequency of triplet UAAs in frame 1 increases obviously near the start codon compared with the distributions in frame 2 and 3 .

序列分析发现拼接的cDNA含有一个411bp的开放阅读框，编码136个氨基酸，ATG为起始密码子、TAA为终止密码子。

Sequence analysis revealed that splicing of the cDNA contained a 411 bp open reading frame , encoded 136 amino acids , and ATG was the initiation codon and TAA was the stop codon .

结论针对IGF-IR基因mRNA序列起始密码子及下游序列所设计的反义寡核苷酸能有效阻止mRNA的翻译功能，使其蛋白产物表达下调，达到封闭或减弱该基因表达的目的。

Conclusion Our data suggest that antisense ODNs complementary to the initiation codon of IGF-IR mRNA and its downstream sequence can effectively prevent the translation of the target mRNA into protein product , thus block or weaken the expression of IGF-IR .

序列分析的结果表明，此3.1kb外源片段中存在一长度为1347bp的完整的开放阅读框架（ORF），起始密码子为ATG，终止密码子为TGA，共编码448个氨基酸。

Sequence analysis revealed that the open reading frame of mcr gene was 1 347 bp in size , encoding 448 amino acids with ATG as initiation codon and TGA as termination codon .

发现酵母基因编码区和已知DRF的起始密码子总是位于长距离不出现终止密码的位置序列上游紧邻最后一个终止密码子的ATG；

This result shows that the starting codon of yeast gene is always the ATG which is in close neighbor to the last terminal codon upstream .

经基因序列分析表明牲畜链霉菌中IPNS基因，由963bp组成，起始密码子为ATG，终止密码子为TGA，共编码321个氨基酸，所克隆的牲畜链霉菌IPNS基因编码蛋白与已知的S。

DNA sequencing revealed that the IPNS gene of S. cattleya consists of 963 bp encoding a protein of 321 amino acids with ATG as start codon , TGA as stop codon .

核苷酸序列分析结果表明，该片段全长3657bp，以GTG为起始密码子，编码一个ORF。

Analysis of the pyc sequence shows that only one ORF exists , which codes 1140 amino acids using GTG as the initiation codon and TAA as the termination codon .

北京地区汉族人群降钙素受体基因、维生素D受体基因起始密码子和Ⅰ型胶原基因SP1转录结合位点多态性与骨密度关系的研究

Allelic Variants of Human Calcitonin Receptor , Vitamin D Receptor Start Codon and SP1 Binding Site of COL1A1 : Distribution and Association with Bone Mineral Density in Adults of Han Nationality in Beijing Area

为了验证电子克隆序列的正确性，在其起始密码子区域和终止密码区域设计特异引物，经RT-PCR进行克隆、序列分析验证，结果表明与电子克隆序列完全一致（GenBank登录号为DQ431246）。

To examine the accuracy of in silico cloning cDNA sequence , we cloned SLA-DMB gene by RT-PCR and sequenced a cDNA fragment covering the coding region of it ( GenBank Accession , DQ431246 ) .

结果表明，翻译起始密码子ATG上游3.9kb的启动子控制的GUS基因在转基因水稻种子胚乳、叶和茎等多个组织中都能表达，但表现出一定的胚乳特异性。

The results showed that the LKR / SDH promoter with a 3.9 kb length upstream of translation initiation codon ATG could drive the expression of GUS gene in endosperm , leaf and stem of transgenic rice plants , and prefer a certain endosperm-specific expression .

距起始密码子ATG77bp处的T碱基为可能的转录起始位点。

Results showed a base T , 77 bp away from the initiation codon ATG for translation , was the possible initiation site for transcription .

进一步序列分析表明，此特异条带大小为663bp，具有起始密码子和终止密码子，编码220个氨基酸，定名为orf220。

The sequencing result shows it is a 663 bp fragment with its own initiation and termination codons , presumably encoding for 220 amino acids ( named orf 220 ) .

该模型的运行分为初始化、转录、判定起始密码子、判定终止密码子和翻译等五个阶段。

The operation of this model can be divided into five stages : initialization , transcription , determination of the start codon , determination of the stop codons , and translation .

本论文研究的主要结果如下：1.本论文于国内外首次利用目标起始密码子多态性标记技术来研究花生属材料的遗传多样性和亲缘关系。

The main results of this investigation were obtained as follows : 1 In the present study , SCoT polymorphism marker technique was firstly used to study the genetic diversity and relationships among sixteen accessions of genus Arachis .

E.coli和Yeast基因起始与终止密码子邻近序列碱基保守性、关联性的对比研究

The Contrast Study of Base ′ s Conservative Character and Correlative Character between E.coli and Yeast Gene for Adjacent Sequence of Initiation Codon or Termination Codon

真核基因起始与终止密码子旁侧序列的特征对于确定cDNA开放阅读框架（ORF）和预测基因组序列中的编码区（CDS）非常重要。

The characters of sequence flanking the start codon and stop codon in eukaryotic genes play an important role in defining the open reading frame ( ORF ) in cDNA sequences and coding region ( CDS ) in genomic DNA sequences .

但对核小体结合模体的相对偏好性进行比较后发现，转录起始位点、转录终止位点、起始密码子和终止密码子附近±500bp的序列所包含的偏好的核小体结合模体模式数各不相同。

Comparison of relative preference of nucleosome binding motifs shows that the mode number of preferred nucleosome motifs in ± 500bp region around the transcription start sites , transcription termination sites , start codon and stop codon is different .