起始位点

5′RACE分析确定其转录起始位点是269nt处的A。

Transcriptional initiation site A , which is at the 269 nucleotide , was preliminarily determined by using 5 ′ RACE method .

分离植物目的基因全长cDNA和启动子的新方法&快速定位转录起始位点（RITIS）（英文）

Isolation of Full-length cDNA and Promoter of Target Gene from Plant by Rapid Identification of Transcriptional Initiation Site ( RITIS )

基于支持向量机识别真核生物DNA中的翻译起始位点

SVM based recognition of translation initiation sites in eukaryotic DNA

烟草花叶病毒装配起始位点反义RNA表达型中间载体的构建

Construction of Intermediate Vector Expressing Antisense RNA Gene for the Assembly Origin of TMV-RNA

实验结果表明基于数据优化法的SVM分类器在翻译起始位点的辨识上可获得比其他判别方法更好的效果。

Experiment results show that data optimization based SVM is better than other methods .

对于脊椎动物以及人类的mRNA序列，运用核糖体扫描模型预测其翻译起始位点得到了很好的预测率。

By using of ribosome scanning model , high accuracy in vertebrates and human mRNA sequences is obtained .

转录因子一般是与DNA上游序列特别是临近基因转录起始位点结合的蛋白质，通过调节或抑制转录机制来调节基因的表达。

Transcription factors are the protein normally binding the upstream DNA sequences , especially near the transcription start site . They regulate the expression of protein by regulating the transcription mechanism or inhibiting transcription .

转录因子结合位点的长度通常为5到20bp，相对于基因的转录起始位点（transcriptioninitialsite，TIS）有多种位置。

TFBS is usually 5 to 20 bp in length and situated variously relative to the transcription initial site ( TIS ) of a given gene .

结合位置权重矩阵（PWM，positionweightmatrix）和开放阅读框架（ORF，Openreadingframe）的长度分布特征建立了简单的方法识别翻译起始位点，此方法能很好地区分上游AUG和TIS。

Based on the position weight matrix ( PWM ) and length distribution of open reading frame ( ORF ), a simple method for predicting translation initiation sites is presented . It can identify TIS from upstream AUGs easily .

通过RT-PCR的方法确定OsGCS基因的转录起始位点可能位于翻译起始位点（ATG）上游211bp处。

The putative transcription start site ( TSS ) confirmed by RT-PCR was located 211 bp upstream of the translation start codon ' ATG ' ( Fig.5 ) .

该方法通过对转录起始位点（TSS）信息，调控区、编码区组成成分特征信息及CpG岛相关信息的综合来预测人类基因组启动子。

The method makes predictions of promoter by combining information about transcription start sites ( TSS ), compositional features in coding and regulatory regions and CpG islands .

应用体外转录模型，即通过构建T7及T7TIAR的碱基序列及部分退火的双链模型，合成了一段ODN，其包含单链的TIAR结合位点和1个T7的起始位点。

Using an in vitro model of transcription , we synthesized an ODN that contains a single-stranded TIAR binding site and a T7 promoter site .

与病毒因子作用的转录调控顺式元件主要存在于翻译起始位点ATG上游-159～-309区段内。

And the main m-acting elements for viral factors are located in the nucleotide sequence between - 159 to - 309 bp upstream the translation initiation site .

通过PCR方法对克隆的两个启动子进行定点突变，使转录起始位点上游-137bp处A突变为C，得到两个突变启动子（IPMl、IPMs）。

By artificially changing A to C at - 137 bp site upstream from transcription start point of cloned promoter , two site-mutation promoters , IPM s ( 603 bp ) and IPM 1 ( 900 bp ) were created .

这一研究结果回答了长久以来关于NMDA受体装配起始位点的疑问：NMDA受体的装配并不像AMPA受体一样，起始于ATD结构域的二聚化，而更有可能是由受体跨膜区决定的。

This result suggested that NMDA receptor assembly is not as AMPA receptor , starting at the ATD domain dimerization , but more likely to be determined by the transmembrane region .

缺失突变分析将PC1基因启动子上受p53负调控的区域定位在翻译起始位点上游757bp～323bp之间。

Deletion and mutation analyses mapped the region of the PC-1 promoter which was negatively regulated by p53 between the 757 bp ~ 323 bp which was upstream of the translation initiation site .

此外有35条序列在CDS字段标注的翻译起始位点前存在起始密码子ATG，我们分析可能是RefSeq数据库中对其标注有误，其正确性有待进一步考证和研究。

In addition , another initiator codon ATG was found preceding the translation initiation site marked in ' CDS ' in 35 mRNAs . We doubted the marker and it needs further investigation .

首先利用RT-PCR和引物延伸方法确定了hb1f（nr5a2）基因的转录起始位点，并通过序列缺失方法鉴定出hb1f（nr5a2）基因的核心启动子。

We determined the transcription start site ( TSS ) of hb1f ( nr5a2 ) gene via RT-PCR and primer extension and then identified the promoter of hb1f ( nr5a2 ) gene , which exhibited high hepatocyte specific activity .

与其它测定基因转录起始位点的方法相比，RLM-RACE方法更快捷、简便、准确。

RLM-RACE ( RNA ligase-mediated rapid amplification of 5 ′ and 3 ′ cDNA ends ) is more rapid and simple comparing with the common methods for determining gene transcription initiation sites .

但对核小体结合模体的相对偏好性进行比较后发现，转录起始位点、转录终止位点、起始密码子和终止密码子附近±500bp的序列所包含的偏好的核小体结合模体模式数各不相同。

Comparison of relative preference of nucleosome binding motifs shows that the mode number of preferred nucleosome motifs in ± 500bp region around the transcription start sites , transcription termination sites , start codon and stop codon is different .

实验结果表明，与正常脱硫基因启动子活性相比，脱硫基因转录起始位点上游300bp启动子序列具100℅活性，150bp为42%，小于75bp活性为0。

The results showed that the desulfurization gene transcription start site upstream 300 bp promoter sequences with 100 % activity , 150 bp to 42 % , less than 75 bp for 0 , compared with the normal dsz promoter activity in strain R-8 .

翻译起始位点位于第一个外显子。

The translation start site is located in the first exon .

基于滑动窗口的原核转录起始位点计算定位方法

Computational location of transcription start sites in prokaryotic genome based on sliding window

蛋白质卷曲起始位点的搜索

Searching for Protein Folding Initiation

前人实验结果显示转录因子的结合位点多分布在基因转录起始位点上游区域。

Identification of transcription factor binding sites is an important step towards the understanding of the transcription regulation .

目的初步了解STK11/LKB1的转录起始位点信息，分析其可能的候选启动子区段，为以后进行STK11/LKB1的转录调控研究作准备。

Objective To map the approximate transcription initiation site of STK11 / LKB1 and identify its potential promoter region .

这说明它们是一个基因的两个转录本，使用了不同的转录起始位点。

It hints that HSEI and HSEII are two transcripts of HSE gene transcribed from the different transcription start sites .

该算法首先根据转录起始位点可能出现位置的先验信息合理确定搜索范围。

This localization algorithm firstly limits the rational searching ranges in genomic sequences based on the prior information of TSSs occurrence .

看家基因转录边界和翻译边界区域，核小体结合模体在转录起始位点附近序列上出现频数最高。

In transcription and translation boundary region , nucleosome binding motifs show the highest frequency in the vicinity of the transcription start site .

核糖体蛋白基因转录起始位点附近碱基信息分析汉坦病毒包膜糖蛋白糖基化位点突变体的构建

Analysis of Base Information Round the TSS of Ribosomal Protein Genes ; Construction of N-linked glycosylation site mutants of envelope glycoprotein genes of hantavirus